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Top St. Charles hotels deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Free cancellation
Reserve now, pay when you stay
The price is CA $231 per night
CA $231
per night
May 15 - May 16
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for Ameristar Casino Resort and Spa along with the latest prices and availability – book now.
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street, St. Charles, MO
Free cancellation
Reserve now, pay when you stay
The price is CA $125 per night
CA $125
per night
Apr. 28 - Apr. 29
Stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for Best Western Plus The Charles Hotel along with the latest prices and availability – book now.
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

Get rates
Stay at this family-friendly vacation home in St. Charles. Enjoy free WiFi, a water park, and onsite parking. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for The St. Charles Guest House, lovely historic home, fun for families and groups, in St. Charles Historic District neighborhood, along with the latest prices and availability – book now.
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz, St. Charles, MO
Free cancellation
Reserve now, pay when you stay
The price is CA $196 per night
CA $196
per night
May 12 - May 13
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and WiFi. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for Embassy Suites by Hilton St. Louis St. Charles along with the latest prices and availability – book now.
Country Inn & Suites by Radisson, St. Charles, MO

Country Inn & Suites by Radisson, St. Charles, MO

2.5 out of 5
1190 S Main St, St. Charles, MO
Free cancellation
The price is CA $172 per night
CA $172
per night
May 12 - May 13
Stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for Country Inn & Suites by Radisson, St. Charles, MO, in St. Charles Historic District neighborhood, along with the latest prices and availability – book now.
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive, St. Charles, MO
Free cancellation
Reserve now, pay when you stay
The price is CA $170 per night
CA $170
per night
Apr. 28 - Apr. 29
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby. Discover genuine guest reviews for Drury Plaza Hotel St. Louis St. Charles along with the latest prices and availability – book now.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Image for St. Louis Union Station

St. Louis Union Station

4.5/5(7 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Image for Busch Stadium

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium
Image for St. Louis Zoo

St. Louis Zoo

4.5/5(7 reviews)

Why not visit the animals who live at St. Louis Zoo and see why this is a popular attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.

St. Louis Zoo

St. Charles Vacations

Make meaningful memories, embark on incredible adventures and take the path less traveled — it's all possible in St. Charles. But first, let us give you some basic details about your next vacation destination!

St. Charles is a neighborhood in the much-loved city of St. Louis. To get there, travel 18 miles (29 kilometers) northwest of the center of town.

Ready to meet some of the locals? 320,000 people call St. Louis home.

Hotels in St. Charles

Book with Travelocity and stay within strolling distance of St. Charles' best attractions. However, with just 6 properties to pick from, you'll need to move fast to secure the best room.

Compare the amenities at the Ameristar Casino Resort and Spa (1 Ameristar Blvd) and the Comfort Suites St Charles-St Louis (1400 S 5th St). These delightful accommodations are in demand with many travelers.

Places to visit in St. Charles

Famous for its architectural features, beautiful grounds and age-old traditions, Lindenwood University is steeped in history. Walk around the faculties and take in the timeless atmosphere. Seeking more nearby options? Opulent decor, magical lights and charming staff are just some of the things you'll discover at Ameristar Casino St. Charles. Take a walk around the tables or simply sit back with a cocktail in hand and enjoy the atmosphere. And that's not all. History is bursting with stories to be told and major lessons to be learned. Stop by First Missouri State Capitol Historic Site and take a journey into the past.

Where do you fly into for St. Charles?

Pack your bags and get ready for an exciting adventure. When you disembark at Lambert-St. Louis International Airport (STL), you'll be just 7 miles (11 kilometers) east of St. Charles.

Frequently asked questions

How much are vacation packages to St. Charles?
You’ll find an awesome flight and hotel bundle for as low as . With one of our Travelocity vacation packages, a trip to St. Charles has never been more tempting! Save your time and money and then start packing those bags.
Where can I get the best vacation package deals for St. Charles?
You’ll discover an amazing range of St. Charles package deals on Travelocity. With as many as 400 air carriers and 665,000 worldwide properties, arranging your dream escape will be simple.
Why should I purchase my St. Charles vacation bundle via Travelocity?
Because you’ll never wander alone if you lock in your vacation with us, and we offer round-the-clock support and excellent service to boot. Add to that our Price Match Guarantee and a huge range of destinations and experiences to choose from. It’s our job to help you have the vacation of a lifetime.
Can I save on my St. Charles car rental if I book it with a hotel or flight?
You certainly can with our St. Charles vacation packages. With one of these, there are lots of ways to make your vacation budget go further. Combine any two or more car, hotel, flight and tour bookings and watch the savings start to pile up. With your own ride, all the attractions in and around St. Charles are a fun road trip away.
What is the best time of year to go to St. Charles?
If you’d like to avoid costly airfares, tourist hordes and overbooked hotels, organize your escape outside of . The quietest time to travel to St. Charles is . You’ll find hotel prices are the highest in and the most affordable in .
What is there to do in St. Charles?
Grab your vacation itinerary and make time for Ameristar Casino St. Charles and St Charles Convention Center. They are some of the best-known sights in St. Charles.
Where should I stay when visiting St. Charles?
If you want to maximize your travel budget, check out the Red Roof Inn St Louis - St Charles (2.0 stars) and the Super 8 by Wyndham St Charles (2.0 stars). With all that extra cash, you’ll be able to linger a while longer in St. Charles and make even more special memories.
Can I go on vacation to St. Charles at this time?
Don’t head to St. Charles without up-to-date facts about travel restrictions and quarantine policies. Travelocity’s Covid-19 Travel Advisor will fill you in. Our travel experts have pulled together all the info you need to make your vacation plans as hassle-free as possible.