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Book Exclusive Cayo Santa Maria Vacation Packages
Cayo Santa Maria flight + hotel packages
Price found within the past 48 hours. Click for updated prices.
![Mayfair House Hotel & Garden](https://images.trvl-media.com/lodging/1000000/30000/24400/24311/8140bb16_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Mayfair House Hotel & Garden
Coconut Grove
per person
Sep. 30 - Oct. 4
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Miami (MIA)
Book a stay at this boutique hotel in Miami. Enjoy a rooftop terrace, breakfast (surcharge), and room service. Our guests praise the bar and the property condition in our reviews. Popular attractions Brickell City Centre and Bayside Marketplace are located nearby.
![1 Hotel South Beach](https://images.trvl-media.com/lodging/2000000/1800000/1790100/1790087/5f494a59_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
1 Hotel South Beach
South Beach
per person
Oct. 2 - Oct. 9
found 6 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to Miami (MIA)
Stay at this 5-star luxury hotel in Miami Beach. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the property condition in our reviews. Popular attractions Lincoln Road Mall and Collins Avenue Shopping Area are located nearby.
![Rio Hotel & Casino](https://images.trvl-media.com/lodging/1000000/20000/19900/19837/04b00f49_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Rio Hotel & Casino
Save 100% on your flight
per person
Oct. 16 - Oct. 20
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Las Vegas (LAS)
Book a stay at this eco-certified resort in Las Vegas. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the comfy rooms and the overall value in our reviews. Popular attractions Casino at the Rio All-Suite Hotel and Bellagio Casino are located nearby.
![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/857b1c16_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Relais de la Poste
Rome City Centre
Save 100% on your flight
per person
Sep. 7 - Sep. 14
found 7 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Rome (FCO)
Stay at this 3-star property in Rome. Enjoy free WiFi, breakfast (surcharge), and daily housekeeping. Popular attractions Piazza di Spagna and Spanish Steps are located nearby.
![Baglioni Hotel Regina - The Leading Hotels of the World](https://images.trvl-media.com/lodging/1000000/450000/445200/445130/f57ce992_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Baglioni Hotel Regina - The Leading Hotels of the World
Rome City Centre
Save 100% on your flight
per person
Sep. 11 - Sep. 17
found 4 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to Rome (FCO)
Stay at this 5-star luxury hotel in Rome. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions Spanish Steps and Piazza di Spagna are located nearby.
Top Cayo Santa Maria hotels deals
![Villa Gaviota Cayo Coco](https://images.trvl-media.com/lodging/16000000/15480000/15478900/15478888/d700d8e1_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Villa Gaviota Cayo Coco
Ciego de Avila, Cayo Santa Maria
Stay at this hotel in Cayo Santa Maria. Popular attraction Playa Las Gaviotas is located nearby.
![Grand Memories Santa Maria - All Inclusive](https://images.trvl-media.com/lodging/19000000/18410000/18409000/18408916/355414f4_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Grand Memories Santa Maria - All Inclusive
Municipio Caibarien, Cayo Santa Maria, Villa Clara
Stay at this 3.5-star beach property in Cayo Santa Maria. Enjoy free breakfast, free parking, and 5 restaurants. Popular attraction Playa Las Gaviotas is located nearby.
Pool
Breakfast included
![Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive](https://images.trvl-media.com/lodging/19000000/18990000/18989300/18989293/a42bdb2e_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Cayo Santa Maria, Cayo Santa Maria, Villa Clara
Stay at this 3.5-star beach property in Cayo Santa Maria. Enjoy free breakfast, free parking, and 5 restaurants. Popular attraction Playa Las Gaviotas is located nearby.
Pool
Breakfast included
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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![Cayo Santa Maria](https://mediaim.expedia.com/destination/1/70305e9e961afdbaa22d6bad116f5a73.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)
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