Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Cayo Santa Maria Vacations

If you’re planning a trip to Cayo Santa Maria, Travelocity will guide you to the perfect vacation. From helping you find hotels in Cayo Santa Maria, flights, and car rental, Travelocity is here to help you soak up every moment of your trip to Cayo Santa Maria.

Top Cayo Santa Maria Flight + Hotel packages

Top Cayo Santa Maria Hotels Deals

See all 8 Hotels in Cayo Santa Maria
Valentin Perla Blanca - All Inclusive - Adults Only

Valentin Perla Blanca - All Inclusive - Adults Only

Lagunas del Este III, Cayo Santa Maria
4.5 out of 5.0

Nestled on the beach, this Cayo Santa Maria resort is 8.4 mi (13.5 km) from Cayo Santa Maria Dolphinarium and 13.8 mi (22.2 km) from Cayo Los Brujas.

C$160

C$160
Starfish Cayo Santa Maria - All Inclusive

Starfish Cayo Santa Maria - All Inclusive

Cayo Santa Maria, Cayo Santa Maria
4.0 out of 5.0

Nestled on the beach, this Pueblo La Estrella resort is 4.5 mi (7.2 km) from Cayo Santa Maria Dolphinarium and 9.9 mi (15.9 km) from Cayo Los Brujas.

Villa Gaviota Cayo Coco

Villa Gaviota Cayo Coco

Ciego de Avila, Cayo Santa Maria

Situated in Cayo Santa Maria, this hotel is 3.4 mi (5.5 km) from Cayo Santa Maria Dolphinarium and 8.8 mi (14.2 km) from Cayo Los Brujas.

Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive

Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive

Cayo Santa Maria, Cayo Santa Maria
5.0 out of 5.0

Nestled on the beach, this Pueblo La Estrella resort is 5 mi (8.1 km) from Cayo Santa Maria Dolphinarium and 10.4 mi (16.7 km) from Cayo Los Brujas.

Grand Memories Santa Maria - All Inclusive

Grand Memories Santa Maria - All Inclusive

Municipio Caibarien, Cayo Santa Maria
4.0 out of 5.0

Nestled on the beach, this Pueblo La Estrella resort is 4.8 mi (7.8 km) from Cayo Santa Maria Dolphinarium and 10.2 mi (16.5 km) from Cayo Los Brujas.

C$173

C$173
Golden Tulip Aguas Claras Resort

Golden Tulip Aguas Claras Resort

Playa Las Caletas, Cayo Santa Maria
4.0 out of 5.0

Situated in Cayo Santa Maria, this hotel is 7.9 mi (12.8 km) from Cayo Santa Maria Dolphinarium and 13.3 mi (21.4 km) from Cayo Los Brujas.

Sercotel Experience Cayo Santa Maria - All Inclusive

Sercotel Experience Cayo Santa Maria - All Inclusive

Cayo las Brujas, Cayo Las Brujas
4.5 out of 5.0

Nestled on the beach, this Cayo Las Brujas resort is 3.9 mi (6.3 km) from Cayo Los Brujas and 4.7 mi (7.5 km) from Cayo Santa Maria Dolphinarium. Caibarien Beach ...

Hotel Break Point

Hotel Break Point

Km 55 carretera a Playa Pilar, Cayo Guillermo
3.5 out of 5.0

Situated in Cayo Guillermo, this hotel is close to Cayo Guillermo Beach. Area attractions also include Cayo Guillermo Marina.