Entire apartment

Guesthouse Charleston: SOUTH (105 B)

Apartment near Medical University of South Carolina in Charleston

Choose dates to view prices

Photo gallery for Guesthouse Charleston: SOUTH (105 B)

Interior
Exterior
Shower, hair dryer, towels
4 bedrooms, iron/ironing board, WiFi, bed sheets
Smart TV

Reviews

10 out of 10
Exceptional

Entire apartment

4 bedrooms5 bathroomsSleeps 10167 sq m

Popular amenities

  • Kitchen
  • Washer
  • Dryer
  • Air conditioning
  • Parking available

Explore the area

View in a map
Charleston, SC
  • Place, Medical University of South Carolina
    ‪8 min walk‬
  • Place, College of Charleston
    ‪12 min walk‬
  • Place, The Citadel
    ‪13 min walk‬
  • Airport, Charleston, SC (CHS-Charleston Intl.)
    ‪15 min drive‬

Room options

You may also like

About the area

Charleston

Seaside stay .Within a 15-minute walk of this Downtown Charleston apartment, you'll find Medical University of South Carolina and College of Charleston. Upper King Design District and Cannon Park are also within half a mile (1 km).

What's nearby

  • Medical University of South Carolina - 8 min walk - 0.7 km
  • College of Charleston - 12 min walk - 1.0 km
  • The Citadel - 13 min walk - 1.2 km
  • Marion Square - 15 min walk - 1.3 km
  • Charleston Music Hall - 15 min walk - 1.3 km

Getting around

  • Charleston Station - 13 min drive
  • Charleston Intl. Airport (CHS) - 15 min drive

Restaurants

  • ‪Bad Bunnies Coffee - ‬2 min walk
  • ‪The Co-Op - ‬5 min walk
  • ‪Sugar Bakeshop - ‬6 min walk
  • ‪Little Line - ‬7 min walk
  • ‪Rivayat Creative Indian - ‬3 min walk

About this property

Guesthouse Charleston: SOUTH (105 B)

Newly Renovated in 2024! Nestled on the second floor of a charming two-unit duplex, this four bedroom, four and a half bathroom home is situated on the coveted Spring Street, just steps away from Cannon Green. Experience comfort and style as you step foot through the front door, where a generously sized kitchen seamlessly opens up to an inviting living room. Each of the four bedrooms are a retreat in itself, all boasting ample space, large closets, and bright, renovated en-suite bathrooms. This four bedroom home boast comfort with plush king and queen beds, complemented by four luxurious bathrooms. Bathrooms include rain shower heads, custom vanities, premium towels, and upscale toiletries. Permit # OP2025-06724

Similar properties

Property amenities

Internet

  • Available in the apartment: WiFi

Parking and transportation

  • Parking on site

Kitchen

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Microwave
  • Oven
  • Refrigerator
  • Stovetop
  • Toaster

Dining

  • Dining table

Bedrooms

  • 4 bedrooms
  • Bedsheets provided

Bathroom

  • 4.5 bathrooms
  • Hair dryer
  • Shower
  • Towels provided

Living spaces

  • Dining table
  • Living room

Entertainment

  • Smart TV

Laundry

  • Laundry facilities
  • Washing machine

Comfort

  • Air conditioning
  • Heating

Pets

  • No pets allowed

Suitability/Accessibility

  • Hardwood flooring in public areas
  • Smoking not allowed

Services and conveniences

  • Iron/ironing board

Location highlights

  • In the city center
  • Near a health/beauty spa
  • Near a hospital
  • Near an outlet shopping mall
  • Near the marina
  • Near the sea

Things to do

  • Water park
  • Birdwatching nearby
  • Ecotours nearby
  • Horseback riding nearby
  • Motor boating nearby
  • Wildlife walks nearby

Safety features

  • Carbon monoxide detector not reported (host has not indicated whether there is a carbon monoxide detector on the property; consider bringing a portable detector)
  • Smoke detector (host has indicated there is a smoke detector on the property)
  • First aid kit
  • Fire extinguisher
  • Deadbolt lock

General

  • Unit size: 1,800 square feet

Policies

Check-in

Check-in time starts at 4:00 PM
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 10:00 AM

Special check-in instructions

You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.

Events

No events allowed

Smoking

Smoking is not permitted

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts cash
Onsite parties or group events are strictly prohibited
Host has not indicated whether there is a carbon monoxide detector on the property; consider bringing a portable detector with you on the trip
Host has indicated there is a smoke detector on the property
Safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts cash. Onsite parties or group events are strictly prohibited. For guests' safety, the property includes a fire extinguisher, a smoke detector, a first aid kit, and a deadbolt lock in each accommodation.

Property is also known as

476269

Frequently asked questions

How close is Guesthouse Charleston: SOUTH (105 B) to the airport?

This apartment is 10.9 mi (15-min drive) away from the Charleston Intl. Airport (CHS) airport, the closest popular airport to the property.

Does Guesthouse Charleston: SOUTH (105 B) have an airport shuttle?

Airport shuttle services are not available at this apartment.

How close is Guesthouse Charleston: SOUTH (105 B) to the beach?

This apartment is 10.8 mi (24-min drive) from Isle of Palms Beach and 11.6 mi (21-min drive) from Front Beach. Don't forget your sunscreen!

Does Guesthouse Charleston: SOUTH (105 B) offer free breakfast?

This apartment does not offer free breakfast.

Is there a casino at Guesthouse Charleston: SOUTH (105 B)?

No, there is no casino at this apartment.

What time is check-in at Guesthouse Charleston: SOUTH (105 B)?

Check-in begins at 4:00 PM.

Is there free parking at Guesthouse Charleston: SOUTH (105 B)?

Free parking is not available at this apartment.

Does Guesthouse Charleston: SOUTH (105 B) have a pool?

This apartment does not have a pool.

Does Guesthouse Charleston: SOUTH (105 B) have a spa?

There are no spa services available at this apartment.

How close is Guesthouse Charleston: SOUTH (105 B) to downtown Charleston?

This apartment is 1.1 mi away from Charleston.

Guesthouse Charleston: SOUTH (105 B) Reviews

Reviews

10

Exceptional

Rating 10 - Excellent. 46 out of 46 reviews
Rating 8 - Good. 0 out of 46 reviews
Rating 6 - Okay. 0 out of 46 reviews
Rating 4 - Poor. 0 out of 46 reviews
Rating 2 - Terrible. 0 out of 46 reviews

10/10

Cleanliness

10/10

Amenities

8.0/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Steve

Liked: Cleanliness, amenities, property conditions & facilities, communication
Excellent location and layout for us.
Stayed 5 nights in Dec 2025
Verified

10/10 Excellent

Margaret M.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Loved the location, loved the open spaces as well as each person having their own room and bath!!! Very well put together home. Will 100% stay again.
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Verified traveller

Liked: Cleanliness, check-in, communication, location, listing accuracy
Great space. Good location.
Stayed 5 nights in Nov 2025
Verified

10/10 Excellent

Stephanie B.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Clean, well designed, close to downtown. Perfect for our stay
Stayed 3 nights in Jul 2025
Verified

10/10 Excellent

Michelle E.

Liked: Cleanliness, check-in, communication, location, listing accuracy
We loved the four bedrooms and 5 bathrooms. The rooms were clean and the beds very comfortable. The living area was great for comfort and conversation. Location was easy access to King St. and parking was great.
Stayed 4 nights in Oct 2025
Verified

10/10 Excellent

akeya s.

Liked: Cleanliness, check-in, communication, location, listing accuracy

We loved our stay!

A very beautiful property!
Stayed 3 nights in Apr 2023
Verified

10/10 Excellent

Laura S.

Liked: Cleanliness, check-in, communication, location, listing accuracy
The host checked in regularly to see if we needed anything. Property was as described, location was great and felt safe, parking was very convenient, and the apartment itself was beautiful. We loved it and would stay there again!
Stayed 3 nights in Nov 2025
Verified

10/10 Excellent

Brett G.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great location

Had a great stay in Charleston. Property was great and we look forward to staying again in the future.
Stayed 3 nights in Jul 2022
Verified

10/10 Excellent

samuel r.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Perfect location

We loved staying here. Exactly what my family needed for our quick Christmas getaway.
Stayed 3 nights in Dec 2021
Verified

10/10 Excellent

mark k.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great Place!

Everything about this rental on VRBO's site is accurate. We were very pleased with our stay and may come back again next year with a larger group.
Stayed 4 nights in May 2024
Verified

10/10 Excellent

Hannah V.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great stay

Everything was as pictured. The unit and location were great!
Stayed 3 nights in Jul 2024
Verified

10/10 Excellent

Lara B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Perfect for a girls weekend.

House was spacious and clean. I would absolutely stay here again.
Stayed 2 nights in Nov 2021
Verified

10/10 Excellent

Ling C.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great house

Very good location that is closed to everywhere.
Stayed 2 nights in Mar 2024
Verified

10/10 Excellent

William S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Incredible

Perfect stay for 4 couples. Great location- walking distance to everything. Every room having its own bathroom is incredible.Highly recommend.
Stayed 3 nights in Jun 2025
Verified

10/10 Excellent

Holly B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Lovely stay

We were very comfortable and thoroughly enjoyed our stay. There was plenty of room and we loved the fact that each bedroom had its own bathroom. The location was convenient to everything we wanted to do in Charleston. We appreciated at large dining table and sitting room area, both of which were requirements.
Stayed 4 nights in Apr 2025
Verified

10/10 Excellent

Temika K.

Liked: Cleanliness, check-in, communication, location, listing accuracy

MUSC visit

We booked this property to be near by to MUSC Hospital. Quick drive great location.
Stayed 3 nights in May 2022
Verified

10/10 Excellent

gretchen b.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Fantastic location and property

Close to all of our favorite places! Clean and quiet and very spacious. We stayed for 10 days and would come back to this location. Loved it and can’t wait to return.
Stayed 11 nights in Mar 2023
Verified

10/10 Excellent

Big S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great spot!!

As advertised- bathrooms in every bedroom.
Stayed 2 nights in Dec 2024
Verified

10/10 Excellent

Kara H.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Girls Trip

Larger than expected rooms and very inviting.
Stayed 3 nights in Aug 2024
Verified

10/10 Excellent

Jordan K.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great Stay!

Visited for a bachelorette trip & everything was perfect. House was very cute, well organized and perfect for our group size- we had 7 women so fit two to a bed with one girl having her own room. Very nice & close to everything we wanted to do without being in a noisy or heavy foot traffic area. Would stay again!
Stayed 3 nights in Jan 2025
Verified

10/10 Excellent

Jaime S.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Area is great - easy walking distance to Charleston sights, accessible food, quiet and clean neighborhood. Having private bathrooms in each room was a major plus. The common area was really great for family games and socializing. The beds were very soft. The bathroom toiletries smelled great. The kitchen is a bit small but has the basics (could be a challenge if cooking meals, but wasn't a problem for our stay because we took advantage of all the great nearby restaurants) - breakfasts and snacks were accommodated at the house easily. The hosts were INCREDIBLE communicators - checked in before and throughout the visit.
Stayed 3 nights in Jan 2026
Verified

10/10 Excellent

BJ D.

Liked: Cleanliness, check-in, communication, location, listing accuracy

First visit to Charleston

The house is close to everything. It’s a well maintained house with everything you need.
Stayed 3 nights in Sep 2023
Verified

10/10 Excellent

Donna H.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great getaway

Excellent choice for 4 women traveling together to shop, dine and sight see the Charleston area. Having plenty of space to relax together with 4 bedrooms w private baths was a huge plus for us. Check in and out was super easy, place was very clean and comfortable. We will definitely rent again when we go back to Charleston.
Stayed 2 nights in Jul 2022
Verified

10/10 Excellent

Bo G.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Wedding guests

Great experience with Guesthouse Charleston. Kerri was attentive, responsive and refreshingly professional. Highly recommend Guesthouse Charleston. Thanks for a great weekend.
Stayed 3 nights in May 2022
Verified

10/10 Excellent

Jennifer S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Amazing

This was the perfect place to stay! Beyond clean! I've never seen a place so clean before. Every room was perfect. We had an amazing time. The location was perfect for us to walk to King street and was an easy drive from the airport. We will definitely be back!
Stayed 3 nights in May 2024