Book Cheap Hotels in Seneca
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Most frequently booked Seneca hotels

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
8.48 km from city centre
The price is CA $149 per night
CA $149
CA $185 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Littlejohn Coliseum and Sloan Tennis Center are located nearby.
Pool
Hot tub

Tru by Hilton Seneca Clemson
13050 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
8.24 km from city centre
The price is CA $139 per night
CA $139
CA $152 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Littlejohn Coliseum and Sloan Tennis Center are located nearby.
Breakfast included
Pet-friendly

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Free cancellation
Reserve now, pay when you stay
0.26 km from city centre
The price is CA $101 per night
CA $101
CA $119 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions The Gauntlet and Toy Train Park are located nearby.
Pool
Breakfast included

Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Free cancellation
Reserve now, pay when you stay
1.85 km from city centre
The price is CA $164 per night
CA $164
CA $181 total
Jan 15 - Jan 16, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gignilliat Community Center and Wyndham Plaza are located nearby.
Pool
Breakfast included

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
Free cancellation
Reserve now, pay when you stay
3.09 km from city centre
The price is CA $100 per night
CA $100
CA $110 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood Shopping Center and Golden Corner Plaza are located nearby.
Pool
Breakfast included

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
7.92 km from city centre
The price is CA $115 per night
CA $115
CA $187 total
Jan 25 - Jan 26, 2026
includes taxes & fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf are located nearby.
Kitchen
Pet-friendly

Fairfield Inn & Suites Seneca Clemson Univ Area
800 BYPASS 123 Seneca SC
Free cancellation
Reserve now, pay when you stay
1.74 km from city centre
The price is CA $170 per night
CA $170
CA $187 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Golden Corner Plaza and Gignilliat Community Center are located nearby.
Pool
Breakfast included

Best Western Seneca-Clemson
511 Bypass Highway 123 Seneca SC
Free cancellation
Reserve now, pay when you stay
1.3 km from city centre
The price is CA $122 per night
CA $122
CA $134 total
Jan 6 - Jan 7, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gignilliat Community Center and The Gauntlet are located nearby.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top family friendly Seneca hotel deals

Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Seneca SC
9/10 Wonderful! (75 reviews)
Top cheap Seneca hotel deals

Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd Seneca SC
The price is CA $100 per night from Jan 11 to Jan 12
CA $100
CA $110 total
Jan 11 - Jan 12, 2026
includes taxes & fees
6.8/10 (721 reviews)
Top hotels in Seneca for Extended Stay

The Inn at Southern Oaks located in Historic Lavonia, GA, close to Lake Hartwell
Lavonia GA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Seneca hotels essential information
Accommodation | 1,654 hotels |
|---|---|
Lowest Price | CA $110 |
Highest Price | CA $187 |
Popular hotels | Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson, Quality Inn Seneca Clemson Area US-123, Hampton Inn & Suites Seneca-Clemson Area, Days Inn by Wyndham Seneca / Clemson Area, Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy, Fairfield Inn & Suites Seneca Clemson Univ Area , Best Western Seneca-Clemson, Fabulous Tiny House with AC in charming Seneca |
Frequently asked questions
Recent Seneca hotel reviews by fellow wanderers

Quality Inn Seneca Clemson Area US-123
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
A verified traveller stayed at Quality Inn Seneca Clemson Area US-123
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