Eastern Panama Vacations 2025/2026 from CA $1,172

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Villa Botero By Casa Mojito B&B

per person

Sep 7 - Sep 14

found 22 hours ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

per person

Sep 12 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Central Hotel Bocas del Toro

Save 100% on your flight

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this 3-star hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and a marina. Popular attractions Bolivar Park and Bocas del Toro Ferry Terminal are located nearby.

The Gray by Wynwood House

Bella Vista

Save 100% on your flight

per person

Sep 8 - Sep 15

found 23 hours ago

Roundtrip flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Punta Caracol Acqua Lodge

Punta Caracol

Save 100% on your flight

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.

Top Eastern Panama hotels deals

Ordovician Beach Resort

Isla Grande, Isla Grande, Colon

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Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

On private beach

Pool

Private Over the Water Cabin on San Blas Island

9.542876, -78.899058, Narganá, San Blas

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Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla Diablo are located nearby.

Breakfast included

Kitchen

Ranchos de Chalia

Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón

CA $191

CA $211 total

Jul 21 - Jul 22

includes taxes & fees

Stay at this 3-star hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island, Narganá, Guna Yala

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Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime are located nearby.

Breakfast included

Restaurant

Ciel y Miel

Caillle Principale, Cacique, Provincia de Colón

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Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island, Narganá, Guna Yala

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Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Isla Chichime are located nearby.

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Cayos Holandeses

Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,172. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.