Book Exclusive Cayo Guillermo Vacation Packages

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Cayo Guillermo flight + hotel packages

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Glendale Hotel
Mayfair House Hotel & Garden
1 Hotel South Beach
The Towers at Lotte New York Palace
The Retreat Collection at 1 Hotel & Homes South Beach

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much are vacation packages to Cayo Guillermo?
Enjoy an unforgettable experience in Cayo Guillermo with a vacation package starting from as low as CA $677. Reserving your tours, flights and hotels with Travelocity is easy. On top of that, our package deals will leave you with extra money for loads of fun activities.
Where can I get the best vacation package deals for Cayo Guillermo?
It’s hard to beat Travelocity when it comes to piecing together your Cayo Guillermo package deal. There are as many as 400 partner airlines and 665,000 properties around the world to choose from. Reserve your trip now and get ready to tick another amazing place off your travel bucket list.
Why should I purchase my Cayo Guillermo vacation bundle with Travelocity?
From enticing destinations to thrilling experiences, we have everything you need to satisfy your love for travel. Our 24/7 customer care will also make sure you’re being well taken care of while you’re on your trip. And don’t stress if you spot a better price on your booking, we’ll match it. That’s our Price Match Guarantee.
Can I save money on my Cayo Guillermo car rental if I book it with a hotel or flight?
You can with our Cayo Guillermo vacation packages. With one of these, there are loads of ways to make your travel budget go further. Bundle any two or more car, flight, hotel and tour bookings and see the savings start to pile up. With your own ride, all the main sights in and around Cayo Guillermo are an unforgettable road trip away.
What is the best time of year to go to Cayo Guillermo?
If you’d rather avoid expensive flights, tourist masses and packed hotels, organize your escape outside of . The quietest time to travel around Cayo Guillermo is . You’ll find the highest hotel prices in and the most economical in .
Can I go on vacation to Cayo Guillermo at this time?
Don’t take off to Cayo Guillermo without the facts about travel restrictions and quarantine policies. Travelocity’s Covid-19 Travel Advisor can fill you in. It has all the info you need to make your vacation plans as relaxed as possible.