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Hotels near Otay Mesa
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free cancellation
Reserve now, pay when you stay
25.71 km from Otay Mesa
The price is CA $208 per night
CA $208
per night
May 27 - May 28
Stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions USS Midway Museum and Petco Park are located nearby. Discover genuine guest reviews for Wyndham San Diego Bayside, in Downtown San Diego neighborhood, along with the latest prices and availability – book now.
Pet-friendly
Pool
Wyndham Garden San Diego Near SeaWorld
3737 Sports Arena Blvd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
31.36 km from Otay Mesa
The price is CA $155 per night
CA $155
per night
May 9 - May 10
Stay at this business-friendly hotel in San Diego. Enjoy free WiFi, onsite parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Marine Corps Recruit Depot and Mission Bay are located nearby. Discover genuine guest reviews for Wyndham Garden San Diego Near SeaWorld, in Point Loma neighborhood, along with the latest prices and availability – book now.
Pool
Parking available
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
33.74 km from Otay Mesa
The price is CA $245 per night
CA $245
per night
May 5 - May 6
Stay at this family-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 poolside bars. Our guests praise the breakfast and the pool in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby. Discover genuine guest reviews for The Dana on Mission Bay along with the latest prices and availability – book now.
Hot tub
Pet-friendly
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free cancellation
24.77 km from Otay Mesa
The price is CA $306 per night
CA $306
per night
May 26 - May 27
Stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. Popular attractions USS Midway Museum and Petco Park are located nearby. Discover genuine guest reviews for Manchester Grand Hyatt San Diego, in Downtown San Diego neighborhood, along with the latest prices and availability – book now.
Pet-friendly
Pool
Paradise Point Resort & Spa
1404 Vacation Rd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
34.51 km from Otay Mesa
The price is CA $301 per night
CA $301
per night
May 27 - May 28
Stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby. Discover genuine guest reviews for Paradise Point Resort & Spa along with the latest prices and availability – book now.
Hot tub
Pet-friendly
Bahia Resort Hotel
998 W Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
34.78 km from Otay Mesa
The price is CA $246 per night
CA $246
per night
May 21 - May 22
Stay at this beach resort in San Diego. Enjoy free parking, a marina, and a beach locale. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby. Discover genuine guest reviews for Bahia Resort Hotel, in Central Mission Beach neighborhood, along with the latest prices and availability – book now.
Hot tub
Pet-friendly
Hard Rock Hotel San Diego
207 5th Ave, San Diego, CA
Free cancellation
Reserve now, pay when you stay
24 km from Otay Mesa
The price is CA $282 per night
CA $282
per night
May 27 - May 28
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Petco Park and USS Midway Museum are located nearby. Discover genuine guest reviews for Hard Rock Hotel San Diego, in Downtown San Diego neighborhood, along with the latest prices and availability – book now.
Pool
Breakfast available
Legacy Resort Hotel & Spa
875 Hotel Circle South, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.87 km from Otay Mesa
The price is CA $197 per night
CA $197
per night
May 22 - May 23
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast. Our guests praise the breakfast and the pool in our reviews. Popular attractions Hotel Circle and San Diego Zoo are located nearby. Discover genuine guest reviews for Legacy Resort Hotel & Spa, in Mission Valley neighborhood, along with the latest prices and availability – book now.
Hot tub
Spa
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
23.7 km from Otay Mesa
The price is CA $212 per night
CA $212
per night
May 28 - May 29
Stay at this 4-star spa hotel in San Diego. Enjoy 2 bars/lounges, a full-service spa, and breakfast. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and USS Midway Museum are located nearby. Discover genuine guest reviews for Hilton San Diego Bayfront, in Downtown San Diego neighborhood, along with the latest prices and availability – book now.
San Diego Mission Bay Resort
1775 E Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
32.92 km from Otay Mesa
The price is CA $295 per night
CA $295
per night
May 27 - May 28
Stay at this beach hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a beach locale. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Hotel Circle are located nearby. Discover genuine guest reviews for San Diego Mission Bay Resort along with the latest prices and availability – book now.
Hot tub
Pet-friendly
Comfort Inn Sea World Area
3880 Greenwood St, San Diego, CA
Free cancellation
Reserve now, pay when you stay
30.77 km from Otay Mesa
The price is CA $129 per night
CA $129
per night
May 5 - May 6
Stay at this hotel in San Diego. Enjoy free breakfast, free WiFi, and onsite parking. Our guests praise the clean rooms in our reviews. Popular attractions Marine Corps Recruit Depot and Hotel Circle are located nearby. Discover genuine guest reviews for Comfort Inn Sea World Area, in Point Loma neighborhood, along with the latest prices and availability – book now.
Pet-friendly
Breakfast included
Best Western Seven Seas
411 Hotel Circle South, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.73 km from Otay Mesa
The price is CA $128 per night
CA $128
per night
May 5 - May 6
Stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 spa tubs. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Hotel Circle and San Diego Zoo are located nearby. Discover genuine guest reviews for Best Western Seven Seas, in Mission Valley neighborhood, along with the latest prices and availability – book now.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Otay Mesa Hotels
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Otay Mesa hotels essential information
Accommodation | 4,495 hotels |
|---|---|
Lowest Price | CA $128 |
Highest Price | CA $306 |
Popular hotels | Wyndham San Diego Bayside, Wyndham Garden San Diego Near SeaWorld, The Dana on Mission Bay, Manchester Grand Hyatt San Diego, Paradise Point Resort & Spa, Bahia Resort Hotel, Hard Rock Hotel San Diego, Legacy Resort Hotel & Spa, Hilton San Diego Bayfront, San Diego Mission Bay Resort, Comfort Inn Sea World Area, Best Western Seven Seas |
Recent Otay Mesa hotel reviews by fellow wanderers
Comfort Inn Sea World Area
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Fantastic property! "
A verified traveller stayed at Comfort Inn Sea World Area
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