Find a cheap Hotel in Otay Mesa

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Hotels near Otay Mesa

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
31.36 km from Otay Mesa
The price is CA $141 per night
CA $141
per night
May 28 - May 29
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Mission Beach Boardwalk are located nearby.
Pool
Parking available
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
25.71 km from Otay Mesa
The price is CA $217 per night
CA $217
per night
May 28 - May 29
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions USS Midway Museum and Petco Park are located nearby.
Pet-friendly
Pool
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.73 km from Otay Mesa
The price is CA $128 per night
CA $128
per night
May 23 - May 24
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 spa tubs. Our guests praise the pool and the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Hot tub
Pool
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
33.74 km from Otay Mesa
The price is CA $244 per night
CA $244
per night
May 23 - May 24
Book a stay at this family-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the breakfast and the pool in our reviews. Popular attractions Mission Beach Boardwalk and Mission Beach are located nearby.
Hot tub
Pet-friendly
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
34.51 km from Otay Mesa
The price is CA $285 per night
CA $285
per night
May 27 - May 28
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
Hot tub
Pet-friendly
Sheraton San Diego Hotel and Marina

Sheraton San Diego Hotel and Marina

4 out of 5
1380 Harbor Island Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.09 km from Otay Mesa
The price is CA $232 per night
CA $232
per night
May 28 - May 29
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions USS Midway Museum and Petco Park are located nearby.
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Free cancellation
24.77 km from Otay Mesa
The price is CA $271 per night
CA $271
per night
May 27 - May 28
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. Popular attractions USS Midway Museum and Petco Park are located nearby.
Pet-friendly
Pool
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
34.78 km from Otay Mesa
The price is CA $227 per night
CA $227
per night
May 30 - May 31
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Beach Boardwalk are located nearby.
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Free cancellation
Reserve now, pay when you stay
24 km from Otay Mesa
The price is CA $285 per night
CA $285
per night
May 27 - May 28
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Petco Park and USS Midway Museum are located nearby.
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.87 km from Otay Mesa
The price is CA $260 per night
CA $260
per night
May 28 - May 29
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
Free cancellation
Reserve now, pay when you stay
29.1 km from Otay Mesa
The price is CA $116 per night
CA $116
per night
May 28 - May 29
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
29.09 km from Otay Mesa
The price is CA $176 per night
CA $176
per night
May 27 - May 28
Book a stay at this golf hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the restaurant in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Don't see what you're looking for?
See all available properties in Otay Mesa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About Otay Mesa Hotels

Search Otay Mesa area hotels for the best deals on Travelocity.ca. Zoom in on Otay Mesa neighborhood to help narrow your hotel selection.

Get Started - Lets Roam Otay Mesa!

Otay Mesa hotels essential information

Accommodation
4,438 hotels
Lowest Price
CA $116
Highest Price
CA $285
Popular hotels
Wyndham Garden San Diego Near SeaWorld, Wyndham San Diego Bayside, Best Western Seven Seas, The Dana on Mission Bay, Paradise Point Resort & Spa, Sheraton San Diego Hotel and Marina, Manchester Grand Hyatt San Diego, Bahia Resort Hotel, Hard Rock Hotel San Diego, Legacy Resort Hotel & Spa, Kings Inn San Diego, Handlery Hotel

Recent Otay Mesa hotel reviews by fellow wanderers

Kings Inn San Diego

Kings Inn San Diego

5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Awesome , convenient, on sute restaurant great. ,big portions , great food in coffee shop. Smoking area perfect , room clean. Beds ok , great location , had problem with reservations, but hotels com resolved quickly. Staff very professional and pleasant, great with smile , coffee shop staff ..awesome.. highly recommend hotel "
A verified traveller stayed at Kings Inn San Diego
Kings Inn San Diego

Hotels near…

Areas of Otay Mesa