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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Hotel near Market Arcade Building in Buffalo

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Lobby sitting area
Business centre
Lobby sitting area
Free daily buffet breakfast

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room

Standard Room

9.2 out of 10
Wonderful
(26 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom

Suite, 1 Bedroom

8.8 out of 10
Excellent
(51 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

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About the area

Buffalo

Downtown Buffalo stay.With a stay at this Downtown Buffalo hotel, you'll be steps from Buffalo Music Hall of Fame and Market Arcade Building. CEPA Gallery and Buffalo Visitor Center are also within half a mile (1 km).

What's nearby

  • Chippewa District - 1 min walk - 0.0 km
  • Market Arcade Building - 1 min walk - 0.0 km
  • Shea's Performing Arts Center - 2 min walk - 0.2 km
  • Buffalo Niagara Convention Center - 6 min walk - 0.6 km
  • Niagara Square - 8 min walk - 0.7 km

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Bada Bing - ‬2 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk
  • ‪Eddie Brady's - ‬3 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel near Market Arcade Building in Buffalo
Public spaces have free WiFi. You'll find a business center on site. Free breakfast is available daily. A fitness center, a vending machine, and laundry facilities are also featured at the business-friendly Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

This Buffalo hotel is smoke free.

  • 146 guestrooms or units
  • 7 levels
  • Buffet breakfast (free)
  • Business facilities
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Elevator
  • No smoking on site
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with safes and coffee/tea makers. Accommodations have separate sitting areas and are furnished with double sofa beds. Cable television is provided. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

Lobby
Wyndham Garden Buffalo Downtown
Downtown Buffalo
  • Breakfast included
  • Free WiFi
  • Restaurant
  • Air conditioning
4.5 out of 5, Wonderful, 1,789 reviews
The price is CA $180
CA $210 total
includes taxes & fees
May 7 - May 8
Wyndham Garden Buffalo Downtown

Property amenities

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 49-inch TV with cable channels

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 18 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. This property uses eco-friendly cleaning products.
    For guests' safety, the property includes a fire extinguisher, a smoke detector, and window guards in each accommodation. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Children 18 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to the airport?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 10.3 mi (21-min drive) away from the Buffalo Niagara Intl. Airport (BUF) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Apr 29, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on May 10, 2026 start from CA $173, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to the beach?

This hotel is 14.8 mi (26-min drive) from Beaver Island Beach.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offer free breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast every day from 6:00 AM to 10:00 AM.

Is there a casino at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no casino at this hotel, but Seneca Buffalo Creek Casino (3-min drive) and Hamburg Gaming at the Fairgrounds (19-min drive) are nearby.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Free parking is not available at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a pool?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG does not have a pool.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a spa?

There are no spa services available at this hotel.

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to downtown Buffalo?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 0.4 mi away from Buffalo.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 562 out of 1002 reviews
Rating 8 - Good. 273 out of 1002 reviews
Rating 6 - Okay. 73 out of 1002 reviews
Rating 4 - Poor. 41 out of 1002 reviews
Rating 2 - Terrible. 53 out of 1002 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

8/10 Good

hector

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 1 night in Feb 2026

2/10 Terrible

Stephanie

Disliked: Cleanliness, amenities, property conditions & facilities
Very disappointing stay. At check-in, the front desk agent was distracted and unprofessional, carrying on another conversation while helping me. The room keys didn’t work, and I had to go back and forth to the front desk multiple times, waiting in long lines each time. It took about 45 minutes just to get into my room, which made me late when I already had somewhere to be. Once inside, the room clearly wasn’t properly cleaned—there were other guests’ hair products on the floor, a hole in the door, and the toilet wouldn’t flush unless you tried several times. Overall, one of the worst hotel experiences I’ve had. Would not recommend.
Stayed 1 night in Jan 2026

10/10 Excellent

Paul

Travelled with group
Liked: Cleanliness, amenities, property conditions & facilities
The room was clean, the staff were AMAZING, especially Mario and Eddie on the front desk!!! I cannot say how incredible the overall experience was. Would highly recommend
Stayed 1 night in Jan 2026

10/10 Excellent

Joseph

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026

6/10 Okay

Patricia

Travelled with family
Liked: Cleanliness
Room noisy as we were on Main Street side with train When we went at 8a for breakfast it was wiped out
Stayed 1 night in Jan 2026

10/10 Excellent

Adam

Liked: Cleanliness, amenities, property conditions & facilities
Clean room
Stayed 1 night in Jan 2026

10/10 Excellent

RYAN

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Rooms were large. Breakfast was good and very friendly and helpful staff
Stayed 1 night in Jan 2026

10/10 Excellent

Timothy

Stayed 1 night in Jan 2026

8/10 Good

Ashley

Stayed 1 night in Jan 2026

10/10 Excellent

Rob

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
There is no on site parking. But weekends there are two side streets right at the hotel free parking on the street. We got a spot close to the front door. There are garage parking options close by. Rooms are spacious well kept and clean. Breakfast was good but since they make a bunch of food it does sit a while so pretty hard to make it all fresh. They had two different omelets. Cereals yogurt sausages and turkey sausage. Fresh cinnamon buns. Bread, muffins. Tea and coffee and white milk as well as chocolate. Plus orange and cranberry juice. So a good cariety
Nice comfy bed. Tv in here as well
Big bathroom
Sitting or work area with work setup stations and pull out couch. Tv in room
Stayed 1 night in Jan 2026

6/10 Okay

Kenneth

Travelled with family
They didnt have the pancake machine working. They also had rattling pipes in the walls all night.
Stayed 5 nights in Jan 2026

10/10 Excellent

Adontaye

Liked: Cleanliness, amenities, property conditions & facilities
Everything was great!
Stayed 1 night in Jan 2026

8/10 Good

Avery

Liked: Cleanliness, staff & service, property conditions & facilities
Friendly staff and clean room, however both bathroom door handles were broken, as well as the blinds.
Stayed 1 night in Dec 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, amenities
Good Stay All Around
Stayed 1 night in Dec 2025

8/10 Good

Neil

Travelled with family
Liked: Cleanliness, amenities, property conditions & facilities
Staff very helpful. No parking on site, less than 5 min. walk to parking garage with a fee, $12 per day.
Stayed 2 nights in Dec 2025

8/10 Good

Connie

Liked: Cleanliness, amenities, property conditions & facilities
The room was very spacious and clean.
Stayed 1 night in Dec 2025

10/10 Excellent

Johnny

Stayed 3 nights in Dec 2025

6/10 Okay

WAI KEI

Stayed 3 nights in Nov 2025

8/10 Good

Daniel

Travelled with family
Liked: Cleanliness, staff & service, amenities
Rooms were clean and the breakfast was very good. Traveled with our kids and 4 grandkids. They had a great time
Stayed 1 night in Dec 2025

6/10 Okay

Peter

Liked: Amenities, property conditions & facilities
Eddy the front desk guy was great . Really helped me out and had alot of knowledge.
Stayed 1 night in Dec 2025

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
In town for a concert, staff very helpful with recommendations for travel and dining
Stayed 1 night in Dec 2025

8/10 Good

Timothy

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Front desk was friendly just not very informative about the breakfast hours. Bathroom fan didnt work and fridge froze stuff
Stayed 1 night in Dec 2025

6/10 Okay

Jennifer, Palmetto

Travelled with family
Liked: Cleanliness
Room was big and heat worked great. Staff was friendly but not so knowledgeable on “things to do” in town or how to get around. Common areas clean. The walls are very thin. Heard every person walking past the door and full on conversation from room next door. The hot water did not work well. We had to turn the shower on for about five minutes to not have ice cold showers.
Stayed 4 nights in Dec 2025

10/10 Excellent

Jordan

Stayed 1 night in Dec 2025

8/10 Good

Frank

Location
Stayed 1 night in Nov 2025