Isla Grande Vacations 2026 from CA $1,158

Isla Grande flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Irresistible City Center

San Francisco

CA $1,158

per person

Jul 9 - Jul 14

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this condo in Panama City. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

CA $1,660

per person

Jul 1 - Jul 5

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

San Francisco

CA $1,404

per person

Jul 1 - Jul 5

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Decapolis Hotel Panama City

San Francisco

CA $1,454

per person

Jul 8 - Jul 12

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Villa Marina Hotel

CA $1,661

per person

Jun 27 - Jul 4

found 6 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Book a stay at this beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.

Top Isla Grande hotels deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

CA $771

CA $849 total

May 31 - Jun 1

includes taxes & fees

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

On private beach

Pool

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Free cancellation

Reserve now, pay when you stay

CA $87

CA $158 total

Jun 2 - Jun 3

includes taxes & fees

Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Pet-friendly

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

CA $152

CA $167 total

Jun 3 - Jun 4

includes taxes & fees

Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Spa

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province Colón Province

CA $468

CA $536 total

May 29 - May 30

includes taxes & fees

Stay at this vacation home in Isla Grande. Enjoy air conditioning. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pet-friendly

Air conditioning

Ocean View Villa with AC + Starlink + BBQ + Private Beach + Kitchen + Parking

Colón Colón

Get rates

Stay at this villa in Isla Grande. Enjoy laundry facilities and air conditioning. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Air conditioning

Laundry

Brother Sun Villas

Camino Al Faro Isla Grande

Get rates

Book a stay at this beach vacation home in Isla Grande. Enjoy a beach locale, daily housekeeping, and a garden. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Kitchen

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Isla Grande?

CA $1,158 is all you need to spend for a memorable vacation in Isla Grande. Bundle your hotel and flights into a vacation package with Travelocity and see your savings add up. With such good prices, it's never been more tempting to travel.

Where can I get the best vacation package deals for Isla Grande?

With around 400 partner airlines and 1,000,000 properties around the world, it's hard to beat Travelocity. Browse our comprehensive range and pick up the best Isla Grande vacation package. Isn't it amazing when trip planning is that easy?

Why should I purchase my Isla Grande vacation package via Travelocity?

Because you'll never roam alone if you secure your trip with us, and we offer round-the-clock support and exceptional service to boot. Add to that our Price Match Guarantee and a massive range of destinations to select from. We're here to help you have the vacation of a lifetime.

Will I save money on my Isla Grande car rental if I bundle it with a hotel or flight?

Certainly. And our Isla Grande vacation packages are the best way to do it. With only a few clicks you can save cash and time by bundling your bookings. Collect the keys to your rental car and feel the freedom of the open road. Need to fill your itinerary? Add some activities or experiences to your package and make savings on those too.