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Featured Santorini 4 Star hotels

Santorini Palace

Santorini Palace

4 out of 5
Fira town Santorini Santorini Island
The price is CA $170 per night from Apr 29 to Apr 30
CA $170
CA $209 total
Apr 29 - Apr 30
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (772 reviews)
I loved my stay at Santorini Palace, this is a really beautiful and well-maintained property, with great views of areas of the island. My room was excellent, clean and comfortable, very spacious and cozy. The staff all over the hotel is friendly and attentive. Food was average, and as everything ...

Reviewed on Apr 22, 2026

Opens in a new windowSantorini Palace
Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only

4 out of 5
Firostefani Santorini Santorini Island
The price is CA $203 per night from Apr 28 to Apr 29
CA $203
CA $247 total
Apr 28 - Apr 29
includes taxes & fees
Book a stay at this spa hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,004 reviews)
View from.the room is stunning, but glass panes/windows were not cleaned so it was a bit frustrating. But a lot of repairs are overdue for the amenities. Staff is helpful and polite, reception /check-in was amicable and helpful.

Reviewed on Apr 26, 2026

Opens in a new windowIra Hotel & Spa - Adults Only
Rocabella Santorini Hotel & SPA

Rocabella Santorini Hotel & SPA

4 out of 5
Imerovigli Santorini Cyclades
Fully refundableReserve now, pay when you stay
The price is CA $112 per night from Apr 29 to Apr 30
CA $112
CA $143 total
Apr 29 - Apr 30
includes taxes & fees
Book a stay at this spa hotel in Santorini. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (655 reviews)
Excellent hospitality and great hotel . I would recommend everyone to stay here and it’s worth the money . As I mentioned in the feedback to the hotel staff the area outside of the rooms can get really slippery during rain or high moisture conditions and the hotel should do something about it like ...

Reviewed on Apr 1, 2026

Opens in a new windowRocabella Santorini Hotel & SPA
El Greco Resort

El Greco Resort

4 out of 5
Fira Santorini Santorini Island
Fully refundableReserve now, pay when you stay
The price is CA $142 per night from Apr 29 to Apr 30
CA $142
CA $178 total
Apr 29 - Apr 30
includes taxes & fees
Book a stay at this beach hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (542 reviews)
Superb resort in Fira Santorini for solo traveller, family or parties. Excellence is their watchword in every department from the moment you check-in until leaving. Thoroughly enjoyable experience and location. Would recommend and hopefully return

Reviewed on Apr 26, 2026

Opens in a new windowEl Greco Resort
Aressana Spa Hotel and Suites

Aressana Spa Hotel and Suites

4 out of 5
Fira Santorini Santorini Island
The price is CA $227 per night from May 4 to May 5
CA $227
CA $274 total
May 4 - May 5
includes taxes & fees
Book a stay at this luxury hotel in Santorini. Enjoy free breakfast, an outdoor pool, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (510 reviews)
the staff was great

Reviewed on Apr 7, 2026

Opens in a new windowAressana Spa Hotel and Suites
Thireas Hotel

Thireas Hotel

4 out of 5
Thira Santorini Cyclades
The price is CA $270 per night from May 1 to May 2
CA $270
CA $322 total
May 1 - May 2
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (382 reviews)
Great location in Fira. Clean room, great view of caldera from our balcony. Pool on the same level. Outdoor table and chairs and 2 sun lounges. Small fridge with minibar. Aircon but didn’t use. Bathroom has shampoo, conditioner, shower gel and bar of soap. Good hair dryer. John organised our taxi ...

Reviewed on Apr 24, 2026

Opens in a new windowThireas Hotel
Hermes Hotel

Hermes Hotel

4 out of 5
Ermis Street, Kamari Santorini Santorini Island
The price is CA $119 per night from May 9 to May 10
CA $119
CA $151 total
May 9 - May 10
includes taxes & fees
Book a stay at this business-friendly hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (200 reviews)
Beautiful hotel space
Variety in the breakfast buffet. Really healthy food selection. Staff were lovely, very courteous. Housekeeping always made swans out of the towel everyday, they cleaned. The grounds are well kept and it was so comfortable hanging out at the hotel.

Reviewed on Oct 22, 2025

Opens in a new windowHermes Hotel
Esperas Santorini

Esperas Santorini

4 out of 5
Oia Santorini
The price is CA $315 per night from Apr 28 to Apr 29
CA $315
CA $374 total
Apr 28 - Apr 29
includes taxes & fees
Book a stay at this luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (323 reviews)
Love balcony, friendly staff and complimentary breakfast was fantastic.

Reviewed on Nov 9, 2025

Opens in a new windowEsperas Santorini
Kalisti Hotel & Suites

Kalisti Hotel & Suites

4 out of 5
Fira Town Santorini Santorini Island
The price is CA $309 per night from May 26 to May 27
CA $309
CA $367 total
May 26 - May 27
includes taxes & fees
Book a stay at this family-friendly hotel in Santorini. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (269 reviews)
Beautiful place, convenient location! Great staff! Would stay again!

Reviewed on Apr 21, 2026

Opens in a new windowKalisti Hotel & Suites
Cliff Side Suites

Cliff Side Suites

4 out of 5
Firostefani Santorini Santorini Island
The price is CA $197 per night from May 1 to May 2
CA $197
CA $240 total
May 1 - May 2
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free WiFi, room service, and a 24-hour front desk. Popular attractions Santorini Caldera and Athinios Port are located ...
9.2/10 Wonderful! (120 reviews)
Beautiful property

Reviewed on Oct 28, 2025

Opens in a new windowCliff Side Suites
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4 Star Hotels Santorini

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Santorini 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Santorini will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Santorini, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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