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Featured Santorini 4 Star hotels

El Greco Resort

El Greco Resort

4 out of 5
Fira, Santorini, Santorini Island
Stay at this 4-star beach hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (528 reviews)

Reviewed on Oct 8, 2025

Opens in a new windowEl Greco Resort
Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only

4 out of 5
Firostefani, Santorini, Santorini Island
The price is CA $138 per night from Nov 1 to Nov 2
CA $138
CA $161 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4-star spa hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,009 reviews)
Good.

Reviewed on Oct 21, 2025

Opens in a new windowIra Hotel & Spa - Adults Only
Ducato di Oia - Adults Only

Ducato di Oia - Adults Only

4 out of 5
Oia Village, Santorini
Stay at this 4-star hotel in Santorini. Enjoy free WiFi, private plunge pools, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (323 reviews)
The location and view is just unbelievable. Views looking out to both the caldera infront of you and also the beautiful Oia buildings behind you. The hot-tub was great too. The porters very friendly and hard-working. Additionally, the hotel staff are available on WhatsApp 24/7 and were so helpful ...

Reviewed on Oct 1, 2025

Opens in a new windowDucato di Oia - Adults Only
Santorini Palace

Santorini Palace

4 out of 5
Fira town, Santorini, Santorini Island
The price is CA $134 per night from Oct 31 to Nov 1
CA $134
CA $169 total
Oct 31 - Nov 1
includes taxes & fees
Stay at this 4-star hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (761 reviews)
Close to lots shopping and eating

Reviewed on Oct 21, 2025

Opens in a new windowSantorini Palace
Villa Manos

Villa Manos

4 out of 5
Karterados, Santorini, Santorini Island
The price is CA $67 per night from Oct 27 to Oct 28
CA $67
CA $93 total
Oct 27 - Oct 28
includes taxes & fees
Stay at this 4-star hotel in Santorini. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (345 reviews)
Property owners were extremely friendly and helpful.

Reviewed on Sep 30, 2025

Opens in a new windowVilla Manos
Afroditi Venus Beach Hotel & Spa

Afroditi Venus Beach Hotel & Spa

4 out of 5
Kamari Beach, Santorini, Santorini Island
Stay at this 4-star beach hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (245 reviews)
Close to airport. Away from major crowding.

Reviewed on Oct 16, 2025

Opens in a new windowAfroditi Venus Beach Hotel & Spa
Agali Houses

Agali Houses

4 out of 5
Firostefani, Santorini, Santorini Island
Stay at this 4-star hotel in Santorini. Enjoy free parking, breakfast (surcharge), and onsite spa services. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (373 reviews)
Couldnt have asked for a better stay

Reviewed on Oct 11, 2025

Opens in a new windowAgali Houses
Esperas Santorini

Esperas Santorini

4 out of 5
Oia, Santorini
The price is CA $261 per night from Oct 27 to Oct 28
CA $261
CA $313 total
Oct 27 - Oct 28
includes taxes & fees
Stay at this 4-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (314 reviews)
Incredible views/sunset! Great patio - small, but functional room. Like alll of Santorini, lots of stairs.

Reviewed on Oct 19, 2025

Opens in a new windowEsperas Santorini
Delion View Hotel

Delion View Hotel

4 out of 5
Fira Caldera, Santorini, Santorini Island
Stay at this 4-star hotel in Santorini. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition in ...
9.4/10 Exceptional! (214 reviews)
The place was cute and quaint. Our balcony had a great view of the caldera as well as the awesome sunset. The staff and service was excellent, especially Alexandros who was very helpful and informative.

Reviewed on Oct 17, 2025

Opens in a new windowDelion View Hotel
Aria Suites

Aria Suites

4 out of 5
Fira, Santorini, Santorini Island
Stay at this 4-star hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.8/10 Exceptional! (283 reviews)
All the staff members, especially the property manager, Stacy were super friendly and nice. This property's location is very convenient to check I and explore Santorini.

Reviewed on Oct 23, 2025

Opens in a new windowAria Suites
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4 Star Hotels Santorini

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Santorini 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Santorini will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Santorini, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Santorini hotel reviews by fellow wanderers