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Top Wayne County hotels deals

Camp Minnow Beach House

Camp Minnow Beach House

Wappapello MO
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Book a stay at this family-friendly cabin in Wappapello. Enjoy a garden, patios, and cable/satellite TV service. Popular attractions Eagle Point Recreation Area and Spillway Recreation Area are located nearby.
Cozy hobby farm cabin under the stars!

Cozy hobby farm cabin under the stars!

Greenville MO
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Stay at this cabin in Patterson. Enjoy laundry facilities and air conditioning.
Private lake, beach & hot tub, romantic getaway or family vaca

Private lake, beach & hot tub, romantic getaway or family vaca

Wappapello MO
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Stay at this vacation home in Wappapello. Enjoy laundry facilities, air conditioning, and a hot tub. Popular attractions Eagle Point Recreation Area and Lake Wappapello are located nearby.
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Free cancellation
Reserve now, pay when you stay
The price is CA $111 per night
CA $111
CA $124 total
Jul 23 - Jul 24
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Free cancellation
Reserve now, pay when you stay
The price is CA $131 per night
CA $131
CA $147 total
Aug 2 - Aug 3
includes taxes & fees
Stay at this hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
Free cancellation
Reserve now, pay when you stay
The price is CA $142 per night
CA $142
CA $160 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Wayne County attractions

A sunset over a lake with boats and ducks.
Photo by JG Morris
Open Photo by JG Morris

Lake Wappapello

8.8/10 (54 reviews)
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
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Photos of local treasures

Browse Wayne County vacation photos for more inspiration

A frozen lake with clear ice and a forested shoreline.
A sunset over a lake with boats and ducks.
A gravel path leading to a stone structure with a triangular roof, surrounded by trees and a road.
A rocky shoreline with a calm lake and distant islands.
A river with people swimming and standing in the water, surrounded by a forested hillside.

Frequently asked questions

How much are vacation packages to Wayne County?
With a Travelocity vacation package, you can live it up in Wayne County for as low as . Flights, hotels and experiences — we've got you covered. You'll save tons just for bundling together your bookings. With all of that taken care of before you even go, you can sit back, relax and not worry about a thing.
Where can I get the best vacation package deals for Wayne County?
For an excellent package deal to Wayne County, book with Travelocity. Choose from 400 airlines and 1,000,000 properties around the world to create your ultimate adventure — you're spoiled for choice!
Why should I book my Wayne County vacation package via Travelocity?
By booking your flights, hotel, car rental and activities altogether, you'll save both time and money. All our bookings come with a dedicated team of experts available 24/7, and you'll know that you'll always be getting the best deal in town with our Price Match Guarantee. So, what's stopping you? Book the vacation of your dreams today and start packing!
Can I save on my Wayne County car rental if I book it with a hotel or flight?
Certainly. And our Wayne County vacation packages are the perfect way to do it. In just a few clicks you can save money and time by combining your bookings. Collect the keys to your rental car then set your own course. Looking for things to do? Add some activities or experiences to your package and make savings on those too.
Which airport is best for Wayne County?
Organizing where you step off the plane in Wayne County is a cinch — most carriers jet in and out of Cape Girardeau Municipal Airport (CGI).
What is there to do in Wayne County?
A diverse and exciting destination, Wayne County boasts some wonderful tourist attractions. Lake Wappapello and Clearwater Lake are a couple of the most popular.