Eastern Panama Vacations 2025/2026 from CA $1,057

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Casa Fofo

CA $1,057

per person

Feb 9 - Feb 16

found 19 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Stay at this guesthouse in San Carlos. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Playa La Ensenada and Playa El Palmar are located nearby.

Central Hotel Bocas del Toro

CA $2,348

per person

Feb 1 - Feb 8

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Stay at this hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and a marina. Popular attractions Bolivar Park and Bocas del Toro Ferry Terminal are located nearby.

Ciel y Miel

CA $1,829

per person

Feb 9 - Feb 16

found 19 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Mahogany Suites

CA $1,290

per person

Dec 24 - Dec 31

found 1 day ago

Roundtrip flight included

Toronto (YTO) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Punta Caracol Acqua Lodge

Punta Caracol

CA $1,628

per person

Feb 1 - Feb 8

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Book a stay at this beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.

Top Eastern Panama hotels deals

Ranchos de Chalia

Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón

CA $158

CA $175 total

Dec 10 - Dec 11

includes taxes & fees

Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Ordovician Beach Resort

Isla Grande Isla Grande Colon

Get rates

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

Free cancellation

Reserve now, pay when you stay

CA $147

CA $177 total

Dec 15 - Dec 16

includes taxes & fees

Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Ciel y Miel

Caillle Principale Cacique Provincia de Colón

Get rates

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Free cancellation

Reserve now, pay when you stay

CA $60

CA $129 total

Nov 24 - Nov 25

includes taxes & fees

Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island Narganá Guna Yala

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Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Isla Chichime are located nearby.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Chichime

Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,057. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.