Eastern Panama Vacations 2025/2026 from CA $1,362

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

CA $1,362

per person

Dec 23 - Dec 30

found 1 day ago

Roundtrip flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Ciel y Miel

CA $1,846

per person

Jan 24 - Jan 31

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

CA $3,914

per person

Jan 24 - Jan 31

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Isla Palenque Member of the Cayuga Collection

CA $3,938

per person

Jan 9 - Jan 13

found 11 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Book a stay at this beach lodge in Boca Chica. Enjoy free WiFi, a full-service spa, and a 24-hour front desk. Popular attractions Boca Chica Marina and Playa Grande are located nearby.

La Concordia Boutique Hotel

Casco Viejo

CA $2,064

per person

Jan 24 - Jan 31

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Top Eastern Panama hotels deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

Get rates

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Ranchos de Chalia

Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón

CA $159

CA $176 total

Nov 29 - Nov 30

includes taxes & fees

Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

Free cancellation

Reserve now, pay when you stay

CA $147

CA $161 total

Dec 15 - Dec 16

includes taxes & fees

Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Spa

Ciel y Miel

Caillle Principale Cacique Provincia de Colón

Get rates

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Free cancellation

Reserve now, pay when you stay

CA $56

CA $124 total

Dec 3 - Dec 4

includes taxes & fees

Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Pet-friendly

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island Narganá Guna Yala

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Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Isla Chichime are located nearby.

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Chichime

Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,362. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.