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Hotels near South Central Houston
InterContinental Houston by IHG
6750 Main St Houston TX
Fully refundable
The price is CA $164 per night from Dec 7 to Dec 8
CA $164
CA $220 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Great staff, clean room
Reviewed on Nov 26, 2025
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $192 per night from Dec 19 to Dec 20
CA $192
CA $239 total
Dec 19 - Dec 20
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
My stay was great. Location was perfect. I wasn’t far from places I needed to uber to. I will be back.
Reviewed on Nov 29, 2025
Houston Marriott Medical Center/Museum District
6580 Fannin Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $248 per night from Jan 3 to Jan 4
CA $248
CA $336 total
Jan 3 - Jan 4, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
The hotel was amazing, not the most convenient for us to go to family but it worked.
Reviewed on Nov 28, 2025
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $666 per night from Dec 13 to Dec 14
CA $666
CA $848 total
Dec 13 - Dec 14
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
Very nice room, great staff, excellent food & drink.
Reviewed on Dec 2, 2025
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $130 per night from Dec 7 to Dec 8
CA $130
CA $153 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
Rice Village Area. Very nice area
Reviewed on Nov 29, 2025
DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $118 per night from Dec 22 to Dec 23
CA $118
CA $139 total
Dec 22 - Dec 23
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
The staff was fantastic! Check-in was fast and the hotel looks updated and well kept. My only concern was that the tap water smelled heavily like sulphur. Not certain if it was a hotel issue or city issue. Great stay overall!
Reviewed on Nov 30, 2025
Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $119 per night from Dec 13 to Dec 14
CA $119
CA $140 total
Dec 13 - Dec 14
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and NRG Stadium are located nearby.
The receptionist was polite and professional. Room was clean, comfortable and updated. Being right off the highway made it convenient to get around Houston and it wasn’t too loud from inside the room. Perfect for a quick two night stay!
Reviewed on Nov 26, 2025
Americas Best Value Inn Medical Center Downtown
2419 Riverside Dr Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $99 per night from Dec 4 to Dec 5
CA $99
CA $116 total
Dec 4 - Dec 5
includes taxes & fees
Stay at this motel in Houston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Parking very small
Reviewed on Nov 25, 2025
Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from Dec 4 to Dec 5
CA $101
CA $118 total
Dec 4 - Dec 5
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Great receptionist. Clean room. Perfect location to access Md Anderson.
Reviewed on Nov 11, 2025
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Recent South Central Houston hotel reviews by fellow wanderers
Hotel Zaza Houston Museum District
5 out of 5
Posted 23 hours ago
Travelocity Verified Review
"Very nice room, great staff, excellent food & drink."
A verified traveller from Austin stayed at Hotel Zaza Houston Museum District
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