Find a cheap Hotel in South Central Houston
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Hotels near South Central Houston

Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $266 per night from Aug 2 to Aug 3
CA $266
CA $361 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
"We were unable to leave the property for medical reasons so we ate at the hotel. The food was good but the menu was very limited. Shuttle service very good and fun ride. Beautiful pool area. Very nice hotel located close to Medical Center. Would stay there again!"
Reviewed on Jul 21, 2026

Houston Marriott Medical Center/Museum District
6580 Fannin Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $201 per night from Jul 24 to Jul 25
CA $201
CA $279 total
Jul 24 - Jul 25
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
"I enjoyed my stay!"
Reviewed on Jul 21, 2026

Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $102 per night from Aug 2 to Aug 3
CA $102
CA $120 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
"The first room we walked in was on the second floor and I could smell the horrible smell before I even made it to the door. It’s smelled like something died so we had to switch rooms and we had a king suite which was downsized to a queen, the room was so small and compact. The tub was outdated it ..."
Reviewed on Jul 20, 2026

Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from Aug 16 to Aug 17
CA $129
CA $153 total
Aug 16 - Aug 17
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...

InterContinental Houston by IHG
6750 Main St Houston TX
Fully refundable
The price is CA $200 per night from Jul 25 to Jul 26
CA $200
CA $262 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...

The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $227 per night from Jul 24 to Jul 25
CA $227
CA $282 total
Jul 24 - Jul 25
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...

DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $171 per night from Jul 26 to Jul 27
CA $171
CA $200 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...

Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Aug 5 to Aug 6
CA $124
CA $145 total
Aug 5 - Aug 6
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.

Sentral Forme Houston
5501 La Branch Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $252 per night from Aug 9 to Aug 10
CA $252
CA $336 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy a 24-hour fitness center, parking (surcharge), and a 24-hour front desk. Popular attractions Toyota Center ...
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Recent South Central Houston hotel reviews by fellow wanderers

Houston Marriott Medical Center/Museum District
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"I enjoyed my stay!"
A verified traveller stayed at Houston Marriott Medical Center/Museum District
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