Find and compare 4 Star hotels in Florida Keys
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Featured Florida Keys 4 Star hotels
Reefhouse Resort & Marina
"Awesome stay!"
Reviewed on Jun 3, 2026
Hawks Cay Resort
"This is really neat and a unique find. The dinner at salt and ash we had was amazing! We were upgraded to a villa and it was decent but the downstairs bathroom was locked and it needed some better cleaning in the bathrooms upstairs and towel racks!!! It wasn’t horrible, but not the best…. I didn’t ..."
Reviewed on Jun 3, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
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Reviewed on Jun 1, 2026
Amara Cay Resort
"Muy buen plan en familia para ir a los cayos. Buena atención y limpieza"
Reviewed on Jun 1, 2026
Islander Resort
"Would definitely stay there, again!"
Reviewed on Jun 3, 2026
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
"The property was beautiful as soon as we pulled up we were greeted by a woman on a golf cart. She was so happy and helpful. It made us feel comfortable right away, showed us to the front desk and she was also so very friendly. I wish I remembered their names. We got an ocean view. It also overlooked ..."
Reviewed on May 30, 2026
Playa Largo Resort & Spa, Autograph Collection
"The place was spectacular. Beach bartenders were great. Definitely will Be back"
Reviewed on May 31, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
"The hot tub was not on the property but was accessible through the property next-door, which was a little bit of a walk. Would have given it five stars if it wasn’t for the terrible individual at check-in. I don’t remember his name, but he stayed in the room in the back, not in the front where he ..."
Reviewed on Jun 1, 2026
La Siesta Resort & Villas
"Fantastic property. Quiet and family friendly."
Reviewed on Jun 2, 2026
Tranquility Bay Beachfront Hotel and Resort
"Me encantó todo, sin duda volveria"
Reviewed on Jun 2, 2026
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Islander Resort
"Would definitely stay there, again!"
