Vacation Homes in Byron
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Featured Vacation Homes in Byron

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Century Cottage-PERFECT for Mayo & downtown visitors!

Rochester House w/ Yard - 5 Minutes to Mayo Clinic

Discounted Oasis! 5 Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!

New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)

Magical Nest Hideaway

Silver Lake Oasis

"Walden Pond" Adventure Amidst 44 Private Acres

1 mi. from Mayo Clinic; Cozy, Clean

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Top trending hotels in Byron

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Vacation Rentals in Byron
What kind of vacation do you want in Byron? The answer to that question will help you choose the right lodging for your stay. The wise wanderer knows that a vacation rental is an essential part of the traveling experience. It’s more than just a place to crash at night—it’s where you wake up in the morning, where you lounge when you’re not exploring, and it’s the starting point for all your adventures. No matter what type of vacation homes strike your fancy, Travelocity has something in Byron that will speak to you.
Do you want a fully equipped kitchen so you can exercise your culinary mastery and impress your travel buddies? How about a romantic terrace for your anniversary trip? Have you always wished to fall asleep to the sound of waves crashing on the shore? One of our vacation home rentals is bound to add that extra magic to your trip. In fact, we’ve got plenty of options lined up just for you in Byron, including luxury vacation rentals. On a budget? We can work with your funds and still give you a great place to sleep at night.
Take a look at what we have on offer. You’ll find rentals close to the big tourist draws, as well as rentals that keep you away from the crowd. Consider vacation rentals a little off the beaten path where you can live like a local and discover hidden gems that never make it to the tourist sites. Book through Travelocity and start your getaway today.
Byron Vacation Homes essential information
Accommodation | 158 Vacation Homes |
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Popular accommodation | Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom, Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown., Century Cottage-PERFECT for Mayo & downtown visitors!, Rochester House w/ Yard - 5 Minutes to Mayo Clinic, Discounted Oasis! 5 Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!, New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic), Magical Nest Hideaway, Silver Lake Oasis, "Walden Pond" Adventure Amidst 44 Private Acres, 1 mi. from Mayo Clinic; Cozy, Clean, Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly, The Best of Southwest Rochester, MN |