Mayo Clinic Florida Vacation Deals: Mayo Clinic Florida, Southside Holidays

Mayo Clinic Florida vacation package deals

Price found within the past 48 hours. Click for updated prices.

Wyndham Garden Jacksonville

Southside

per person

Sep 15 - Sep 18

found 11 hours ago

Roundtrip flight included

Detroit (DTW) to Jacksonville (JAX)

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and EverBank Stadium are located nearby.

Hammock Beach Golf Resort & Spa

per person

Sep 13 - Sep 16

found 1 day ago

Roundtrip non-stop flight included

Moncton (YQM) to Daytona Beach (DAB)

Stay at this 4-star luxury resort in Palm Coast. Enjoy free WiFi, free parking, and 9 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Ocean Hammock Golf Club and Hammock Beach Ocean Course are located nearby.

The Villas of Amelia Island

per person

Sep 15 - Sep 18

found 11 hours ago

Roundtrip flight included

Detroit (DTW) to Jacksonville (JAX)

Stay at this 4-star beach vacation home in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Amelia Island State Park and Fort George Island Cultural State Park are located nearby.

Hampton Inn Jacksonville Beach/Oceanfront

per person

Sep 15 - Sep 18

found 11 hours ago

Roundtrip flight included

Detroit (DTW) to Jacksonville (JAX)

Stay at this 3-star beach hotel in Jacksonville Beach. Enjoy free breakfast, 2 outdoor pools, and a beach locale. Our guests praise the breakfast and the pool in our reviews. Popular attractions Jacksonville Beach Pier and Sleiman North Shopping Center are located nearby.

Ocean Coast Hotel at the Beach Amelia Island

per person

Sep 15 - Sep 18

found 11 hours ago

Roundtrip flight included

Detroit (DTW) to Jacksonville (JAX)

Stay at this 3-star eco-certified hotel in Fernandina Beach. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Seaside Park and Fernandina Beach Pinball Museum are located nearby.

Baymont by Wyndham Jacksonville/Butler Blvd

Southside

per person

Sep 15 - Sep 18

found 11 hours ago

Roundtrip flight included

Detroit (DTW) to Jacksonville (JAX)

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and EverBank Stadium are located nearby.

Frequently asked questions

How much are vacation packages to Mayo Clinic Florida?

If you like the sound of hassle-free planning and huge savings, our CA $616 Mayo Clinic Florida vacation package will be right up your street. With your hotel and flights sorted, organizing your getaway around this much-loved attraction has never been easier.

Where can I get the best vacation package deals for Mayo Clinic Florida?

It's simple — head to Travelocity. With no less than 400 air carriers and 665,000 properties across the globe, it's easy to craft a Mayo Clinic Florida package deal that suits your travel style.

Why should I book my Mayo Clinic Florida vacation package with Travelocity?

Travel should be about making cherished memories and leaving all your stresses behind — which is why we provide you with a professional team of customer service experts available 24/7 should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best price available on our impressive range of destinations. So what are you waiting for? There's no time like the present to secure that vacation you've always wanted.

Can I go on vacation to Mayo Clinic Florida at this time?

We have all the local knowledge to ensure your travel dreams a reality, so before organizing your trip to Mayo Clinic Florida, read through our Covid-19 Travel Advisor. It has the latest info about travel restrictions, quarantine policies and other important details.

Top Mayo Clinic Florida hotel deals

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

14390 Mayo Boulevard, Jacksonville, FL

Free cancellation

Reserve now, pay when you stay

Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions St. Johns Town Center and Jacksonville Beach Pier are located nearby.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

4905 SAN PABLO ROAD SOUTH, Jacksonville, FL

Free cancellation

Reserve now, pay when you stay

CA $242

CA $275 total

Aug 8 - Aug 9

includes taxes & fees

Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and Jacksonville Beach Pier are located nearby.

Fancy private pool home in Jax beach

CA $368

CA $733 total

Aug 11 - Aug 12

includes taxes & fees

Stay at this vacation home in Jacksonville Beach. Enjoy private pools, laundry facilities, and patios. Popular attractions St. Johns Town Center and Jacksonville Beach Pier are located nearby.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.