Find and compare 4 Star hotels in Spartanburg

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Featured Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Fully refundableReserve now, pay when you stay

CA $482

CA $546 total

Sep 13 - Sep 14

includes taxes & fees

Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...

9.6/10 Exceptional! (545 reviews)

"The Hotel has a very unique layout and a Beautiful Art Gallery that sits in the middle of the Lobby! And the Hotel Staff, as well as the Spa Staff all receive 4 Stars!!! They were Absolutely AMAZING!!!!"

Reviewed on Aug 24, 2026

Hotel Hartness

120 Halston Avenue Greenville SC

Fully refundableReserve now, pay when you stay

CA $239

CA $316 total

Sep 14 - Sep 15

includes taxes & fees

Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...

The Westin Poinsett Greenville

120 South Main St Greenville SC

Fully refundableReserve now, pay when you stay

CA $248

CA $285 total

Sep 6 - Sep 7

includes taxes & fees

Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...

9.4/10 Exceptional! (1,008 reviews)

"Clean room, great staff from the reception desk to the housekeeping staff. Everyone went out of their way to make our stay the best."

Reviewed on Aug 23, 2026

Greenville Marriott

One Parkway E Greenville SC

Fully refundableReserve now, pay when you stay

CA $144

CA $164 total

Sep 5 - Sep 6

includes taxes & fees

Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...

Doubletree By Hilton Greenville Airport

125 The Parkway Greer SC

Fully refundableReserve now, pay when you stay

CA $182

CA $206 total

Aug 31 - Sep 1

includes taxes & fees

Stay at this hotel in Greer. Enjoy free parking, breakfast (surcharge), and room service. Popular attractions Haywood Mall and Thornblade Tennis Center are located ...

Landing Apartments Greer - Sugar Creek

3000 Daventry Cir Greer SC

Book a stay at this business-friendly apartment in Greer. Enjoy free parking, an outdoor pool, and a fitness center. Popular attractions Century Park and Crossland ...

9.2/10 Wonderful! (5 reviews)

"Great space to rent versus have a hotel room. The unit was very spacious, clean and comfortable. Our only issue was getting an immediate response with an issue discovered at check in. Because Landing had to contact the onsite office for the apartments, we did not receive the pool pass until half ..."

Reviewed on Jul 23, 2026

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Landing Apartments - Lyman

610 Universal Drive Lyman SC

Book a stay at this business-friendly aparthotel in Lyman. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lyman Amphitheater and Lyman ...

10/10 Exceptional! (1 review)

"Great room that was nice and clean. Smooth check-in."

Reviewed on Jun 1, 2026

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Landing Furnished Apartments - Spartanburg, SC

187 N Church St Spartanburg SC

Book a stay at this business-friendly apartment in Spartanburg. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Spartanburg Art ...

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Randall St , 202/204

202 Randall Street Greenville SC

Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...

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140 Catlin Circle

140 Catlin Circle Greenville SC

Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.