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Featured Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $395 per night from Mar 1 to Mar 2
CA $395
CA $447 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.6/10 Exceptional! (452 reviews)
A wonderful hotel with a friendly staff and beautiful architecture

Reviewed on Feb 19, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
The price is CA $259 per night from Mar 1 to Mar 2
CA $259
CA $284 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,000 reviews)
A dream come true since I was young to stay here. It truly was a lovely Christmas Eve.

Reviewed on Feb 6, 2026

Opens in a new windowThe Westin Poinsett Greenville
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $207 per night from Mar 8 to Mar 9
CA $207
CA $274 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (652 reviews)
The room was really clean, staff very helpful and friendly. The hotel itself was really beautiful. Fitness center had nice equipment (only wish they also had a fan!) but it was well air-conditioned. Illy coffee/espresso in the room - was a plus! Really nice looking restaurant within a quick stroll ...

Reviewed on Feb 21, 2026

Opens in a new windowHotel Hartness
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $156 per night from Mar 1 to Mar 2
CA $156
CA $172 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (626 reviews)
Hospitable staff from the front desk throughout

Reviewed on Feb 21, 2026

Opens in a new windowGreenville Marriott
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
The price is CA $198 per night from Mar 24 to Mar 25
CA $198
CA $218 total
Mar 24 - Mar 25
includes taxes & fees
Stay at this hotel in Greer. Enjoy free parking, breakfast (surcharge), and room service. Popular attractions Haywood Mall and Thornblade Tennis Center are located ...
Opens in a new windowDoubletree By Hilton Greenville Airport
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new windowRandall St , 202/204
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window140 Catlin Circle
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4 Star Hotels Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Spartanburg hotel reviews by fellow wanderers