Cheap Flight Deals to Wytheville VA from CA $280

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

How to find cheap flights to Wytheville?

The cheapest prices found with in the last 7 days for return flights were CA $343 and CA $280 for one-way flights to Wytheville for the period specified. Prices and availability are subject to change. Additional terms apply

Sat, Jan 10 - Mon, Jan 19
DTW
Detroit Metropolitan Wayne County
ROA
Roanoke Regional
CA $343 Roundtrip, found 4 hours ago
CA $343
Roundtrip
found 4 hours ago
Select Delta flight, departing Sat, Jan 10 from Detroit Metropolitan Wayne County to Roanoke Regional, returning Mon, Jan 19, priced at CA $343 found 4 hours ago
Mon, Mar 9 - Sat, Mar 14
YYZ
Pearson Intl.
ROA
Roanoke Regional
CA $635 Roundtrip, found 3 days ago
CA $635
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Mar 9 from Pearson Intl. to Roanoke Regional, returning Sat, Mar 14, priced at CA $635 found 3 days ago

Your guide to flights to Wytheville, VA

Delta fly to Wytheville, so use Travelocity to search, find, and compare some truly tempting deals from the 4 airlines—that way you can be sure you’ve found the best deal for you. A flight to Wytheville VA currently costs between CA $343 and CA $635. Prices vary, but for the best fares, travel in January when prices are at their lowest.  

Top tips for finding cheap flights to Wytheville  

The cheapest flight for a round trip to Wytheville is currently CA $343. When you search for flights to Wytheville, enter your preferred travel dates then click on ‘flexible dates’ to compare cheap flight tickets to Wytheville for nearby days.  The cheapest month to travel to Wytheville is January from our list of deals available.  

But if you’re flexible about when you travel, you can find great deals on flights across the year. If you’re planning a vacation, you can save more on Travelocity when you bundle flights with car rental and hotel bookings, too. Many airlines currently offer flexible booking options, so look for flights offering no change fees.   

How to cancel flights to Wytheville 

We know plans change, that’s why at Travelocity, we make it as easy as possible for you to cancel or amend your plane tickets. Go to My Trips, enter your itinerary number, then follow the instructions. Many airlines let you cancel flights online free of charge if you booked it in the last 24 hours. Visit Customer Service for more advice.  

Why you should book your flight to Wytheville with Travelocity 

We have top deals on plane tickets even for last minute flights to Wytheville, so you can simply type in your travel dates and compare our best prices. Booking with Travelocity means you get flexible cancellation options, 24/7 support, and, thanks to our Price Match Promise, if the airfare drops after you book, you can get a refund! Whether you’re planning a business trip, weekend getaway, or a family vacation—let Travelocity get you to Wytheville for less. 

Find The Perfect Hotel For After Your Flight

Amazing Place to Stay After Flight to Wytheville

Quality Inn & Suites

Quality Inn & Suites

2 out of 5
1900 E Main St Wytheville VA
The price is CA $92 per night from Jan 12 to Jan 13
CA $92
per night
Jan 12 - Jan 13
Stay at this hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Wohlfahrt ...
7.4/10 Good! (72 reviews)
For the location (most of the food and gas options are on the other side of Wytheville, but Wytheville isn't that big) and price, this recently renovated Quality Inn was a decent stay. Not a lot of amenities, but the room was in good condition. Only issue is that breakfast is from 6:00-9:00, but ...

Reviewed on Dec 8, 2025

Opens in a new windowQuality Inn & Suites
Red Roof Inn Wytheville

Red Roof Inn Wytheville

3 out of 5
220 Lithia Rd Wytheville VA
The price is CA $85 per night from Jan 4 to Jan 5
CA $85
per night
Jan 4 - Jan 5
Stay at this motel in Wytheville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wohlfahrt Haus Dinner Theatre and Mountainview ...
8.4/10 Very Good! (164 reviews)
The room was very nice. I would stay there again if I ever pass through Wytheville again.

Reviewed on Dec 10, 2025

Opens in a new windowRed Roof Inn Wytheville
Edyn Hotel By Townhouse Wytheville US 52

Edyn Hotel By Townhouse Wytheville US 52

2 out of 5
280 Lithia Rd Wytheville VA
The price is CA $80 per night from Dec 17 to Dec 18
CA $80
per night
Dec 17 - Dec 18
Stay at this hotel in Wytheville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wohlfahrt Haus Dinner Theatre and Mountainview ...
6.6/10 (301 reviews)
Nice clean room exactly as pictured. Nice pool, sauna and hot tub. Wonderful host. Would stay here again.

Reviewed on Oct 11, 2025

Opens in a new windowEdyn Hotel By Townhouse Wytheville US 52
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Days Inn by Wyndham Wytheville

Days Inn by Wyndham Wytheville

2 out of 5
150 Malin Dr, I-81 and I-77 Exit 73 Wytheville VA
The price is CA $84 per night from Dec 18 to Dec 19
CA $84
per night
Dec 18 - Dec 19
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,000 reviews)
Everything about that hotel is good, for money you pay!

Reviewed on Dec 6, 2025

Opens in a new windowDays Inn by Wyndham Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Wytheville

Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

2.5 out of 5
955 Peppers Ferry Rd Wytheville VA
The price is CA $81 per night from Dec 29 to Dec 30
CA $81
per night
Dec 29 - Dec 30
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (1,497 reviews)
The room was great and the staff was very helpful.

Reviewed on Dec 1, 2025

Opens in a new windowRamada by Wyndham Wytheville
Travel Lite Motel

Travel Lite Motel

2 out of 5
655 East Main Street Wytheville VA
Stay at this motel in Wytheville. Enjoy free parking, a 24-hour front desk, and cable TV channels. Popular attractions Edith Bolling Wilson Birthplace Museum ...
7.2/10 Good! (180 reviews)
The staff was friendly and very accommodating

Reviewed on Oct 8, 2025

Get rates
Opens in a new windowTravel Lite Motel
Quality Inn & Suites

Quality Inn & Suites

2 out of 5
1900 E Main St Wytheville VA
The price is CA $92 per night from Jan 12 to Jan 13
CA $92
per night
Jan 12 - Jan 13
Stay at this hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Wohlfahrt ...
7.4/10 Good! (72 reviews)
For the location (most of the food and gas options are on the other side of Wytheville, but Wytheville isn't that big) and price, this recently renovated Quality Inn was a decent stay. Not a lot of amenities, but the room was in good condition. Only issue is that breakfast is from 6:00-9:00, but ...

Reviewed on Dec 8, 2025

Opens in a new windowQuality Inn & Suites
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Red Roof Inn Wytheville

Red Roof Inn Wytheville

3 out of 5
220 Lithia Rd Wytheville VA
The price is CA $85 per night from Jan 4 to Jan 5
CA $85
per night
Jan 4 - Jan 5
Stay at this motel in Wytheville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Wohlfahrt Haus Dinner Theatre and Mountainview ...
8.4/10 Very Good! (164 reviews)
The room was very nice. I would stay there again if I ever pass through Wytheville again.

Reviewed on Dec 10, 2025

Opens in a new windowRed Roof Inn Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Wytheville

Country Inn & Suites by Radisson, Wytheville, VA

Country Inn & Suites by Radisson, Wytheville, VA

3 out of 5
697 Peppers Ferry Road Wytheville VA
The price is CA $126 per night from Jan 4 to Jan 5
CA $126
per night
Jan 4 - Jan 5
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,000 reviews)
Here's the deal.....This poor establishment suffered a catastrophic disaster, when apparently a customer hung something heavy on a sprinkler head thing and Holy Smokes! They are under construction! Totally not their fault, I blame Expedia for the fact we searched every option possible for a MUCH ...

Reviewed on Dec 1, 2025

Opens in a new windowCountry Inn & Suites by Radisson, Wytheville, VA
Deluxe Inn Wytheville

Deluxe Inn Wytheville

2.5 out of 5
355 Nye Road Wytheville VA
The price is CA $88 per night from Jan 15 to Jan 16
CA $88
per night
Jan 15 - Jan 16
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.4/10 Good! (1,000 reviews)
This hotel was really nice a lot nicer than I even expected.The hot tub room is exceptional, clean and has a huge hot tub.It's not a best bathtub chat.It's an actual hot tub for 4 or 5 people.It's really nice.I recommend it to anybody

Reviewed on Nov 29, 2025

Opens in a new windowDeluxe Inn Wytheville
Holiday Inn Express and Suites Wytheville by IHG

Holiday Inn Express and Suites Wytheville by IHG

2.5 out of 5
165 Malin Dr Wytheville VA
The price is CA $147 per night from Dec 21 to Dec 22
CA $147
per night
Dec 21 - Dec 22
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
Pool and Hot tub cleaner than ever before. We stay 2 times a year and this happens to be a cleaner stay that normal.

Reviewed on Dec 1, 2025

Opens in a new windowHoliday Inn Express and Suites Wytheville by IHG
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

2.5 out of 5
955 Peppers Ferry Rd Wytheville VA
The price is CA $81 per night from Dec 29 to Dec 30
CA $81
per night
Dec 29 - Dec 30
Book a stay at this business-friendly hotel in Wytheville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the pool ...
8/10 Very Good! (1,497 reviews)
The room was great and the staff was very helpful.

Reviewed on Dec 1, 2025

Opens in a new windowRamada by Wyndham Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a car after flight to Wytheville?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

Which airlines fly to Wytheville?
All set to book the airfare for your exciting vacation to Wytheville? A total of 5 airlines offer flights to this destination. Some of the most sought-after carriers are:

  • American Airlines
  • Delta Air Lines
  • Contour Aviation

Where to stay in Wytheville
Every unforgettable journey begins with a single step — along with a comfortable place to lay your head! Sort out your Wytheville accommodations through Travelocity and you'll have 29 properties to select from.The The Bolling Wilson Hotel, Ascend Hotel Collection and the Travel Lite Motel are our suggested accommodation options. Make a reservation and then you'll be able to get down to the good stuff — booking your amazing getaway experiences.
Places to visit in Wytheville
0 Seeking some more ideas? 0 But that's not all. 0
How to get through airport security fast when traveling to Wytheville
These handy tips and pointers about airport security procedures will save you a lot of time on your journey to Wytheville:

  • Have your boarding pass and passport somewhere accessible. They'll be the first things you'll be asked to produce by airport security.
  • USB sticks, wallets and wrist watches are to be placed in a tub for X-raying. If you pass through the body scanner with any one of these items, you'll be turned around and requested to remove them.
  • Laptops, tablets and other electronic devices must be placed in a tray to be X-rayed.
  • Traveling with your favorite perfume? As long as it contains no more than 3.4 ounces (100 milliliters) and it's stored in a clear resealable plastic bag, you can keep it with you in your carry-on luggage.
  • Untie your shoelaces as you approach the body scanner. Depending on the type of shoes you've got on, security may instruct you to take them off.
  • Razors and knives are prohibited inside the aircraft. Tuck them away in your checked luggage to avoid losing them at the security checkpoint.

Plane Tickets To Wytheville

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Wytheville. Browse through our inventory to explore a wide range of cheap flights to Wytheville to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Wytheville as you anxiously await to exit the plane and explore what Wytheville has to offer. Considering all the amazing local food and culture in Wytheville, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Wytheville to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Wytheville without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Wytheville with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Wytheville today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.