Find and compare 4 Star hotels in Hyannis

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Featured Hyannis 4 Star hotels

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
1225 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $326 per night from Jun 22 to Jun 23
CA $326
CA $454 total
Jun 22 - Jun 23
includes taxes & fees
Book a stay at this spa resort in Hyannis. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the clean rooms in our reviews. Popular attractions ...
8.8/10 Excellent! (597 reviews)
"awesome stay"

Reviewed on Jun 16, 2026

Opens in a new windowMargaritaville Resort Cape Cod
The Mansion at Ocean Edge

The Mansion at Ocean Edge

4 out of 5
2907 Main Street Brewster MA
The price is CA $523 per night from Jun 21 to Jun 22
CA $523
CA $680 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this luxury hotel in Brewster. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"A beautiful place!"

Reviewed on Jun 13, 2026

Opens in a new windowThe Mansion at Ocean Edge
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

4 out of 5
135 Route 28 West Yarmouth MA
Fully refundableReserve now, pay when you stay
The price is CA $278 per night from Jun 21 to Jun 22
CA $278
CA $330 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this beach hotel in West Yarmouth. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. ...
9.4/10 Exceptional! (169 reviews)
"All good!"

Reviewed on Jun 15, 2026

Opens in a new windowUncommoner Hotel by Reverie Boutique Collection
AutoCamp Cape Cod

AutoCamp Cape Cod

4 out of 5
836 Palmer Avenue Falmouth MA
The price is CA $211 per night from Jun 22 to Jun 23
CA $211
CA $298 total
Jun 22 - Jun 23
includes taxes & fees
Stay at this holiday park in Falmouth. Enjoy free WiFi, free parking, and free bicycles on site. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (342 reviews)
"We enjoyed our stay in an Adventure tent. Very comfortable bed. Just enough of a camping feel with the conveniences of a high end hotel. Super-fresh granola in the morning. The club house is spacious and modern with two showers in the bathroom. Unfortunately only one was working and had to wait. ..."

Reviewed on Jun 17, 2026

Opens in a new windowAutoCamp Cape Cod
Chatham Wayside Inn

Chatham Wayside Inn

4 out of 5
512 Main St Chatham MA
The price is CA $706 per night from Jun 24 to Jun 25
CA $706
CA $869 total
Jun 24 - Jun 25
includes taxes & fees
Book a stay at this golf hotel in Chatham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.2/10 Wonderful! (692 reviews)
"From start to end, this was a wonderful stay! Bar and food excellent too"

Reviewed on Jun 18, 2026

Opens in a new windowChatham Wayside Inn
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

4 out of 5
287 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $310 per night from Jun 21 to Jun 22
CA $310
CA $355 total
Jun 21 - Jun 22
includes taxes & fees
Stay at this hotel in Hyannis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Main ...
8.4/10 Very Good! (911 reviews)
"Clean rooms. Comfy bed!"

Reviewed on Jun 14, 2026

Opens in a new windowDoubletree by Hilton Cape Cod - Hyannis
Queen Anne Inn

Queen Anne Inn

4 out of 5
70 Queen Anne Rd Chatham MA
Fully refundableReserve now, pay when you stay
The price is CA $376 per night from Jun 23 to Jun 24
CA $376
CA $430 total
Jun 23 - Jun 24
includes taxes & fees
Stay at this hotel in Chatham. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Veterans ...
8.8/10 Excellent! (239 reviews)
"It is an old property and very tired. Not very clean."

Reviewed on Jun 9, 2026

Opens in a new windowQueen Anne Inn
Starlight Lodge Cape Cod

Starlight Lodge Cape Cod

4 out of 5
203 Main St Dennis MA
Stay at this lodge in Dennis. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Mayflower Beach and The Club at Yarmouthport are located ...
8.2/10 Very Good! (26 reviews)
"Room was so cozy. We really liked it for an off season visit."

Reviewed on Dec 1, 2025

Opens in a new windowStarlight Lodge Cape Cod
Captain's House Inn

Captain's House Inn

4 out of 5
369 Old Harbor Road Chatham MA
Stay at this B&B in Chatham. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chatham Shark Center and Chatham Seaside Links are located ...
9.8/10 Exceptional! (227 reviews)
"We love this place. Beautiful rooms, common facilities and grounds. Exceptionally friendly and helpful staff. Highly recommended."

Reviewed on Jun 18, 2026

Opens in a new windowCaptain's House Inn
Winstead Inn

Winstead Inn

4 out of 5
116 Parallel Harwich MA
Book a stay at this beach guesthouse in Harwich. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Ocean Edge Golf Club and Cape Cod ...
9.4/10 Exceptional! (133 reviews)
"."

Reviewed on Jun 17, 2026

Opens in a new windowWinstead Inn
Don't see what you're looking for?
See all available properties in Hyannis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Hyannis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Hyannis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Hyannis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Hyannis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Hyannis hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity