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Featured Hyannis 4 Star hotels

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
1225 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $170 per night from Mar 16 to Mar 17
CA $170
CA $272 total
Mar 16 - Mar 17
includes taxes & fees
Book a stay at this spa resort in Hyannis. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the clean rooms in our reviews. Popular attractions ...
8.6/10 Excellent! (477 reviews)
No amenities included.Housekeeping knocked on our door at 9am even though we had a do not disturb on the door.The hotel and check in staff was awesome

Reviewed on Mar 8, 2026

Opens in a new windowMargaritaville Resort Cape Cod
Chatham Wayside Inn

Chatham Wayside Inn

4 out of 5
512 Main St Chatham MA
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in Chatham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.2/10 Wonderful! (638 reviews)
We booked the Hotel, called to check on the room as there was a Power outage in the area due to snow. We were told on the phone the room was ready. We arrived, went to check in. The women a reception informed us "You know we have no electricity, hot water, all facilities were closed. They were were ...

Reviewed on Mar 3, 2026

Opens in a new windowChatham Wayside Inn
The Mansion at Ocean Edge

The Mansion at Ocean Edge

4 out of 5
2907 Main Street Brewster MA
The price is CA $204 per night from Mar 15 to Mar 16
CA $204
CA $311 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this luxury hotel in Brewster. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
Clean room, friendly staff, great food and drinks at Bayzo’s Pub.

Reviewed on Mar 1, 2026

Opens in a new windowThe Mansion at Ocean Edge
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

4 out of 5
287 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $172 per night from Apr 5 to Apr 6
CA $172
CA $197 total
Apr 5 - Apr 6
includes taxes & fees
Stay at this hotel in Hyannis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Hyannis ...
8.4/10 Very Good! (894 reviews)
Clean

Reviewed on Feb 28, 2026

Opens in a new windowDoubletree by Hilton Cape Cod - Hyannis
AutoCamp Cape Cod

AutoCamp Cape Cod

4 out of 5
836 Palmer Avenue Falmouth MA
The price is CA $149 per night from Apr 2 to Apr 3
CA $149
CA $225 total
Apr 2 - Apr 3
includes taxes & fees
Stay at this holiday park in Falmouth. Enjoy free WiFi, free parking, and free bicycles on site. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (306 reviews)
We had a wonderful stay here on Valentine’s Day weekend. It was the first time we stayed at a camp ground and definitely the first time staying in an AirStream. The clubhouse was sooo nice! Staff were great. Good menu options and merch as well. Picked up an AutoCamp beanie! Live music was awesome. ...

Reviewed on Feb 17, 2026

Opens in a new windowAutoCamp Cape Cod
Captain's House Inn

Captain's House Inn

4 out of 5
369 Old Harbor Road Chatham MA
Stay at this B&B in Chatham. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chatham Shark Center and Chatham Seaside Links are located ...
9.8/10 Exceptional! (215 reviews)
Great place to stay in Chatham. Went for First Night celebrations and the Inn was clean and comfortable and served one of the best breakfasts! Highly recommend!

Reviewed on Jan 3, 2026

Opens in a new windowCaptain's House Inn
Starlight Lodge Cape Cod

Starlight Lodge Cape Cod

4 out of 5
203 Main St Dennis MA
Stay at this lodge in Dennis. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Mayflower Beach and The Club at Yarmouthport are located ...
8.2/10 Very Good! (26 reviews)
Room was so cozy. We really liked it for an off season visit.

Reviewed on Dec 1, 2025

Opens in a new windowStarlight Lodge Cape Cod
The Inn At Cape Cod

The Inn At Cape Cod

4 out of 5
4 Summer Street Yarmouth Port MA
Book a stay at this beach B&B in Yarmouth Port. Enjoy free breakfast, free parking, and daily housekeeping. Popular attractions Mayflower Beach and Hyannis Harbor ...
Opens in a new windowThe Inn At Cape Cod
Winstead Beach Resort

Winstead Beach Resort

4 out of 5
4 Braddock Street Harwich Port MA
Book a stay at this beach B&B in Harwich Port. Enjoy free breakfast, free parking, and a private beach. Popular attractions Bank Street Beach and Harwich Port ...
Opens in a new windowWinstead Beach Resort
Sea Street Inn

Sea Street Inn

4 out of 5
328 Sea St Hyannis MA
The price is CA $328 per night from Mar 10 to Mar 11
CA $328
CA $375 total
Mar 10 - Mar 11
includes taxes & fees
Stay at this B&B in Hyannis. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Hyannis Harbor and Keyes Memorial Beach are located ...
9.8/10 Exceptional! (45 reviews)
Adrian was amazing!

Reviewed on Sep 11, 2025

Opens in a new windowSea Street Inn
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4 Star Hotels Hyannis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Hyannis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Hyannis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Hyannis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Hyannis hotel reviews by fellow wanderers