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Featured San Diego 4 Star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $267 per night from May 14 to May 15
CA $267
CA $376 total
May 14 - May 15
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,539 reviews)
The hotel was very nice. The only negative, is that the hotel is starting to show it's age.

Reviewed on Apr 13, 2026

Opens in a new windowHard Rock Hotel San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is CA $316 per night from May 7 to May 8
CA $316
CA $441 total
May 7 - May 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,850 reviews)
Wonderful stay! I recommend renting from in house Enterprise!

Reviewed on Apr 14, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $287 per night from May 10 to May 11
CA $287
CA $403 total
May 10 - May 11
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,548 reviews)
This resort was better than expected. My husband my daughter and I stayed for 3 days and wish we would have booked even just one more. The whole resort is so beautiful and convenient. You can walk to the restaurants there which are amazing and the pools in each village is awesome. We really loved ...

Reviewed on Apr 14, 2026

Opens in a new windowParadise Point Resort & Spa
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $202 per night from May 10 to May 11
CA $202
CA $230 total
May 10 - May 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,307 reviews)
All went well. Everyone was super nice. Bartenders were professional. Room was clean and in good condition as expected. The only disappointment was the fact that the cafe was not open for lunch on our departure.

Reviewed on Apr 14, 2026

Opens in a new windowDoubleTree by Hilton San Diego - Del Mar
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $277 per night from Apr 19 to Apr 20
CA $277
CA $392 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,620 reviews)
It was ok , rooms weren’t cleaned consistently

Reviewed on Apr 14, 2026

Opens in a new windowHyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $209 per night from May 12 to May 13
CA $209
CA $291 total
May 12 - May 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,108 reviews)
We stayed for an event and we had to wait 1hour to be checked in while there was 3 staff members chatting in the corner and the line was out the door. We also were offered an upgrade for our room which we paid for to have a balcony and they gave us the balcony where you couldn’t even step outside ...

Reviewed on Apr 14, 2026

Opens in a new windowWyndham San Diego Bayside
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4 out of 5
660 K St San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $233 per night from May 10 to May 11
CA $233
CA $270 total
May 10 - May 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
8.8/10 Excellent! (1,659 reviews)
Our room was huge. The beds were extremely comfortable. Lots of space in the bathroom. We had a delicious breakfast. My only wish is that there was a better wine selection on the 22nd floor bar. House wine only - Marriott, you can do better

Reviewed on Apr 14, 2026

Opens in a new windowSan Diego Marriott Gaslamp Quarter
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
The price is CA $343 per night from Apr 16 to Apr 17
CA $343
CA $394 total
Apr 16 - Apr 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,589 reviews)
Staying at the Lafayette is always a truly magical experience. We continue to come back because the staff is fantastic and so attentive, the atmosphere is exceptional, the rooms are clean and there is so much to do and eat right on the property.

Reviewed on Apr 14, 2026

Opens in a new windowLafayette Hotel & Club
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $203 per night from May 3 to May 4
CA $203
CA $303 total
May 3 - May 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Opens in a new windowSheraton San Diego Resort
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $321 per night from Apr 23 to Apr 24
CA $321
CA $435 total
Apr 23 - Apr 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,149 reviews)
We enjoyed our visit

Reviewed on Apr 13, 2026

Opens in a new windowOmni San Diego Hotel at the Ballpark
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4 Star Hotels San Diego

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Diego 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Diego will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Diego, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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