Book Exclusive Seneca Vacation Packages

Choose one or more items to build your trip:

Seneca flight + hotel packages

Price found within the past 48 hours. Click for updated prices.
Budget Inn Greenville By Hotel O I-85 

Budget Inn Greenville By Hotel O I-85 

2.5 out of 5
Price was CA $921, price is now CA $871 per person
CA $871
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Stay at this hotel in Greenville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Falls Park on the Reedy and Bon Secours Wellness Arena are located nearby.
Hotel Hartness

Hotel Hartness

4 out of 5
Price was CA $1,428, price is now CA $1,224 per person
CA $1,224
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions BMW Performance Center and Topgolf Greenville are located nearby.
Holiday Inn Greenville - Woodruff Road by IHG

Holiday Inn Greenville - Woodruff Road by IHG

3 out of 5
Price was CA $1,115, price is now CA $1,035 per person
CA $1,035
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Bon Secours Wellness Arena and Falls Park on the Reedy are located nearby.
Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was CA $1,143, price is now CA $1,069 per person
CA $1,069
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Book a stay at this family-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bon Secours Wellness Arena and Falls Park on the Reedy are located nearby.
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
Greenville Downtown
Price was CA $1,442, price is now CA $1,376 per person
CA $1,376
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Falls Park on the Reedy and Bon Secours Wellness Arena are located nearby.

Top Seneca hotels deals

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $154 per night
CA $154
CA $191 total
Sep 28 - Sep 29
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Memorial Stadium and Littlejohn Coliseum are located nearby.
Pool
Hot tub
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
The price is CA $131 per night
CA $131
CA $206 total
Oct 4 - Oct 5
includes taxes & fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreation Area and Cross Creek Plantation Golf are located nearby.
Kitchen
Pet-friendly
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Free cancellation
The price is CA $107 per night
CA $107
CA $126 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Applewood Shopping Center and Golden Corner Plaza are located nearby.
Pool
Breakfast included
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $174 per night
CA $174
CA $191 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Memorial Stadium and Gignilliat Community Center are located nearby.
Pool
Breakfast included
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $150 per night
CA $150
CA $165 total
Oct 18 - Oct 19
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Memorial Stadium and Littlejohn Coliseum are located nearby.
Breakfast included
Pet-friendly
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

3 out of 5
800 BYPASS 123 Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $183 per night
CA $183
CA $201 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Golden Corner Plaza and Gignilliat Community Center are located nearby.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Seneca attractions

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Stroll along this family-friendly area's lakeside, or simply enjoy its coffeehouses.
See properties

Seneca Vacations

Even if you're the most impulsive traveler, it's still a wise idea to find out a few things about Seneca before you go. Highlight it on your map, make a list of the things to do there and let the fun begin!

Seneca is a neighborhood in Anderson. To get there, travel 20 miles (32 kilometers) northwest of the center of town.

Ready to meet some of the locals? 27,000 people call Anderson home.

Places to visit in Seneca

Are you ready to head out into nature and have a bit of fun? The Anderson region is home to some fabulous activities to throw yourself into, such as cycling. If you're looking for more action, jump at the chance to go shore fishing too.

Where do you fly into for Seneca?

Admire the scenic views as you approach Greenville-Spartanburg International Airport (GSP). Collect your baggage, pass through security and you'll be around 45 miles (72 kilometers) east from the middle of Seneca.

Frequently asked questions

How much are vacation packages to Seneca?
Vacation packages, which include hotels and flights in Seneca, are priced from as little as CA $871. Turn your travel fantasies into reality and secure your dream vacation with Travelocity today.
How long should my Seneca vacation be?
If you're looking for some guidance, most travelers spend around 2 nights in Seneca. But to discover the true spirit of this destination, stay a little longer. You'll be able to explore more and really take in the local culture.
Where can I get the best vacation package deals for Seneca?
There's no need to look any further than Travelocity. With 400 air carriers and 1,000,000 properties worldwide, it's a breeze to put together a Seneca package deal that satisfies your wanderlust.
Why should I book my Seneca vacation package via Travelocity?
Because life is one amazing journey, and we've got everything you could hope for to help you along the way. With our first-rate service and Price Match Guarantee, you can book your trip with confidence. Plus, you can sleep easy while you're on the road knowing we're always available to chat via our round-the-clock support.
Will I save money on my Seneca car rental if I bundle it with a hotel or flight?
Bundling your car, hotel and flight into a Seneca vacation package is a great way to score an incredible deal. Plus, having your own car rental gives you freedom to find your way to all the landmarks you can't wait to explore. Situated 137 kilometers from Seneca, Dollywood is one attraction that should be on your itinerary. Load up the car and make a day trip of it.
Which airport is best for Seneca?
For many wanderers, a trip to Seneca means passing through Greenville-Spartanburg Intl. Airport (GSP). This popular airport is 72 kilometers east of the city center. You could also jet into Asheville Regional Airport (AVL) (88 kilometers away from central Seneca) or Athens, GA (AHN-Ben Epps) (88 kilometers away from central Seneca).
Where should I stay when visiting Seneca?
Many visitors stay at the Lakeside Lodge Clemson. It's a terrific base for your Seneca escape.

Photos of local treasures

Browse Seneca vacation photos for more inspiration

A calm lake with mountains in the background.
A sunset over a lake surrounded by dense forests and residential areas.
A calm lake with mountains in the background and a sunset.
A sunset over a calm lake with a silhouette of a forested island in the distance.
A lakeside scene with autumn foliage, a clear sky, and a sunset.