Book Exclusive Seneca Vacation Packages

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Seneca flight + hotel packages

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Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
Price was CA $1,267, price is now CA $932 per person
CA $932
per person
Apr 28 - May 5
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room service in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Landing Apartments - Lyman

Landing Apartments - Lyman

3 out of 5
Price was CA $1,539, price is now CA $1,189 per person
CA $1,189
per person
Apr 28 - May 5
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Greenville (GSP)
Stay at this aparthotel in Lyman. Enjoy free parking, an outdoor pool, and a 24-hour fitness center. Popular attractions Lyman Amphitheater and Lyman Park are located nearby.
Holiday Inn Greenville - Woodruff Road by IHG

Holiday Inn Greenville - Woodruff Road by IHG

3 out of 5
Price was CA $1,301, price is now CA $1,038 per person
CA $1,038
per person
Apr 28 - May 5
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.

3 out of 5
Price was CA $1,524, price is now CA $1,245 per person
CA $1,245
per person
Apr 28 - May 5
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.

Top Seneca hotels deals

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $148 per night
CA $148
CA $183 total
Feb 14 - Feb 15
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Littlejohn Coliseum and Sloan Tennis Center are located nearby.
Pool
Hot tub
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $167 per night
CA $167
CA $184 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gignilliat Community Center and Wyndham Plaza are located nearby.
Pool
Breakfast included
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $141 per night
CA $141
CA $156 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Littlejohn Coliseum and Sloan Tennis Center are located nearby.
Breakfast included
Pet-friendly
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
The price is CA $94 per night
CA $94
CA $163 total
Feb 17 - Feb 18
includes taxes & fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf are located nearby.
Kitchen
Pet-friendly
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $106 per night
CA $106
CA $124 total
Feb 17 - Feb 18
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions The Gauntlet and Toy Train Park are located nearby.
Pool
Breakfast included
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
Free cancellation
Reserve now, pay when you stay
The price is CA $93 per night
CA $93
CA $103 total
Feb 15 - Feb 16
includes taxes & fees
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood Shopping Center and Golden Corner Plaza are located nearby.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

High Shoals Falls in South Mountains State Park

High Falls County Park

High Falls County Park is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Stroll along this family-friendly area's lakeside, or simply enjoy its coffeehouses.

High Falls County Park
Lovely shot of the Blue Ridge Mountains in the distance, with a rural pasture in the foreground, in late summer when the grass is starting to turn yellow and brown. Upstate South Carolina scene.

Blue Ridge Field

Blue Ridge Field is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's lakeside or attend a sporting event.

Blue Ridge Field

South Cove Park

South Cove Park is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels? Stroll along the lakeside or attend a sporting event in this family-friendly area.

South Cove Park

Seneca Vacations

Even if you're the most impulsive traveler, it's still a wise idea to find out a few things about Seneca before you go. Highlight it on your map, make a list of the things to do there and let the fun begin!

Seneca is a neighborhood in Anderson. To get there, travel 20 miles (32 kilometers) northwest of the center of town.

Ready to meet some of the locals? 27,000 people call Anderson home.

Places to visit in Seneca

Are you ready to head out into nature and have a bit of fun? The Anderson region is home to some fabulous activities to throw yourself into, such as cycling. If you're looking for more action, jump at the chance to go shore fishing too.

Where do you fly into for Seneca?

Admire the scenic views as you approach Greenville-Spartanburg International Airport (GSP). Collect your baggage, pass through security and you'll be around 45 miles (72 kilometers) east from the middle of Seneca.

Frequently asked questions

How much are vacation packages to Seneca?
Vacation packages, which include hotels and flights in Seneca, are priced from as little as CA $932. Turn your travel fantasies into reality and secure your dream vacation with Travelocity today.
How long should my Seneca vacation be?
If you're looking for some guidance, most travelers spend around 2 nights in Seneca. But to discover the true spirit of this destination, stay a little longer. You'll be able to explore more and really take in the local culture.
Where can I get the best vacation package deals for Seneca?
There's no need to look any further than Travelocity. With 400 air carriers and 1,000,000 properties worldwide, it's a breeze to put together a Seneca package deal that satisfies your wanderlust.
Why should I book my Seneca vacation package via Travelocity?
Because life is one amazing journey, and we've got everything you could hope for to help you along the way. With our first-rate service and Price Match Guarantee, you can book your trip with confidence. Plus, you can sleep easy while you're on the road knowing we're always available to chat via our round-the-clock support.
Will I save money on my Seneca car rental if I bundle it with a hotel or flight?
Bundling your car, hotel and flight into a Seneca vacation package is a great way to score an incredible deal. Plus, having your own car rental gives you freedom to find your way to all the landmarks you can't wait to explore. Situated 137 kilometers from Seneca, Dollywood is one attraction that should be on your itinerary. Load up the car and make a day trip of it.
Which airport is best for Seneca?
For many wanderers, a trip to Seneca means passing through Greenville-Spartanburg Intl. Airport (GSP). This popular airport is 72 kilometers east of the city center. You could also jet into Asheville Regional Airport (AVL) (88 kilometers away from central Seneca) or Athens, GA (AHN-Ben Epps) (88 kilometers away from central Seneca).
Where should I stay when visiting Seneca?
Many visitors stay at the Lakeside Lodge Clemson. It's a terrific base for your Seneca escape.

Photos of local treasures

Browse Seneca vacation photos for more inspiration

Lake Keowee South Carolina
Lake Keowee South Carolina
Sunset at Lake Keowee , Aerial Panorama - Seneca, South Carolina - July 2024
An overlooking view in Seneca, South Carolina
View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.