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Featured Durham 4 Star hotels

JB Duke Hotel

JB Duke Hotel

4 out of 5
230 Science Drive Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $207 per night from Jan 18 to Jan 19
CA $207
CA $235 total
Jan 18 - Jan 19
includes taxes & fees
Stay at this hotel in Durham. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (554 reviews)
Great location and lovely hotel. My son already liked the pickle ball court.

Reviewed on Jan 7, 2026

Opens in a new windowJB Duke Hotel
21c Museum Hotel Durham

21c Museum Hotel Durham

4 out of 5
111 North Corcoran Street Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $224 per night from Feb 1 to Feb 2
CA $224
CA $261 total
Feb 1 - Feb 2
includes taxes & fees
Stay at this hotel in Durham. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (1,005 reviews)
This hotel is our favorite pet-friendly hotel in downtown Durham. During this last visit, I had inadvertently double booked myself a room directly with the hotel and on Expedia. The check-in host was so kind to cancel the room booked directly with the hotel without penalties. I certainly was not ...

Reviewed on Jan 4, 2026

Opens in a new window21c Museum Hotel Durham
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

4 out of 5
2515 Meridian Pkwy Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from Jan 18 to Jan 19
CA $131
CA $149 total
Jan 18 - Jan 19
includes taxes & fees
Stay at this hotel in Durham. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,001 reviews)
Room was very clean, staff was great! Even had extra silverware at the front desk when I needed it.

Reviewed on Jan 7, 2026

Opens in a new windowDoubleTree Suites by Hilton Raleigh - Durham
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

4 out of 5
3001 Cameron Blvd Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $306 per night from Feb 8 to Feb 9
CA $306
CA $347 total
Feb 8 - Feb 9
includes taxes & fees
Book a stay at this boutique hotel in Durham. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (1,003 reviews)
Just a nice atmosphere

Reviewed on Jan 10, 2026

Opens in a new windowWashington Duke Inn & Golf Club
DoubleTree Raleigh Durham Airport at Research Triangle Park

DoubleTree Raleigh Durham Airport at Research Triangle Park

4 out of 5
4810 Page Creek Ln Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from Jan 16 to Jan 17
CA $159
CA $180 total
Jan 16 - Jan 17
includes taxes & fees
Book a stay at this business-friendly hotel in Durham. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (999 reviews)
Beautiful property, staff was very friendly, whole experience was relaxing!

Reviewed on Jan 4, 2026

Opens in a new windowDoubleTree Raleigh Durham Airport at Research Triangle Park
The Durham Hotel

The Durham Hotel

4 out of 5
315 East Chapel Hill Street Durham NC
Fully refundableReserve now, pay when you stay
The price is CA $259 per night from Jan 16 to Jan 17
CA $259
CA $294 total
Jan 16 - Jan 17
includes taxes & fees
Book a stay at this boutique hotel in Durham. Enjoy free WiFi, 2 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (649 reviews)
We stayed here for NYE/New Year's Day, and the front desk team was incredible. They were personable, energetic, responsive, and kind. The Suite is a great choice for a stay--it's spacious and perfectly situated in the hotel. What a great place to close out 2025 and ring in 2026!

Reviewed on Jan 2, 2026

Opens in a new windowThe Durham Hotel
Landing Apartments Durham

Landing Apartments Durham

4 out of 5
545 Foster Street Durham NC
Stay at this aparthotel in Durham. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Fullsteam Brewery and Manbites Dog Theater are located ...
8.6/10 Excellent! (23 reviews)
Awesome experience! The apartment was very clean and surprisingly located to all almost every thing we had planned! Great spot for our 25th Anniversary!!'

Reviewed on Dec 23, 2025

Opens in a new windowLanding Apartments Durham
Arrowhead Inn

Arrowhead Inn

4.5 out of 5
106 Mason Road Durham NC
The price is CA $315 per night from Feb 11 to Feb 12
CA $315
CA $358 total
Feb 11 - Feb 12
includes taxes & fees
Book a stay at this luxury B&B in Durham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (121 reviews)
The building; the accommodations; the staff; the breakfast; the linen!!! There was nothing that would not rate first class. It was our second visit and we plan to make our third later this year.

Reviewed on Jan 1, 2026

Opens in a new windowArrowhead Inn
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4 Star Hotels Durham

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Durham 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Durham will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Durham, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Durham hotel reviews by fellow wanderers