Find and compare 4 Star hotels in Sanford

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Featured Sanford 4 Star hotels

Hilton Orlando/Altamonte Springs

Hilton Orlando/Altamonte Springs

4 out of 5
350 S Northlake Blvd Altamonte Springs FL
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from May 3 to May 4
CA $175
CA $201 total
May 3 - May 4
includes taxes & fees
Book a stay at this business-friendly hotel in Altamonte Springs. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9/10 Wonderful! (1,391 reviews)
very good. will come through again

Reviewed on Apr 20, 2026

Opens in a new windowHilton Orlando/Altamonte Springs
DoubleTree by Hilton Hotel Orlando Downtown

DoubleTree by Hilton Hotel Orlando Downtown

4 out of 5
60 South Ivanhoe Boulevard Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $152 per night from May 2 to May 3
CA $152
CA $171 total
May 2 - May 3
includes taxes & fees
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (3,249 reviews)
Perfect location is your business is downtown and want be off the busy areas. Property is a bit dated but good overall. Friendly staff. Easy access to I-4

Reviewed on Apr 20, 2026

Opens in a new windowDoubleTree by Hilton Hotel Orlando Downtown
Renaissance Orlando Airport Hotel by Marriott

Renaissance Orlando Airport Hotel by Marriott

4 out of 5
5445 Forbes Pl Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $161 per night from May 4 to May 5
CA $161
CA $181 total
May 4 - May 5
includes taxes & fees
Book a stay at this business-friendly hotel in Orlando. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8.8/10 Excellent! (1,002 reviews)
Comparable to a motel with 4-5 times the cost. Shower was less than 2 feet wide, carpet was stained and coming up, counch in room was stained. And directional signage would lead you to nowhere.

Reviewed on Apr 20, 2026

Opens in a new windowRenaissance Orlando Airport Hotel by Marriott
Marriott Orlando Airport Lakeside

Marriott Orlando Airport Lakeside

4 out of 5
7499 Augusta National Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $196 per night from May 4 to May 5
CA $196
CA $221 total
May 4 - May 5
includes taxes & fees
Book a stay at this family-friendly hotel in Orlando. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the pool and ...
9.2/10 Wonderful! (1,714 reviews)
It was ok, but the lobby was so strong of perfumes and cleaners that my mom who has COPD could nut even stand to be on there for even a minute. That was disappointing. And the food in the restaurant was terrible, at least for breakfast anyhow. But the staff was always very friendly. And the pool ...

Reviewed on Apr 18, 2026

Opens in a new windowMarriott Orlando Airport Lakeside
Holiday Inn Express & Suites Sanford- Lake Mary by IHG

Holiday Inn Express & Suites Sanford- Lake Mary by IHG

4 out of 5
4750 W State Road 46 Sanford FL
Fully refundable
The price is CA $142 per night from May 11 to May 12
CA $142
CA $164 total
May 11 - May 12
includes taxes & fees
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,105 reviews)
Great hotel to stay. Very clean, staff was excellent & breakfast every morning.. I'd definitely stay here again when I'm back in town 👍

Reviewed on Apr 20, 2026

Opens in a new windowHoliday Inn Express & Suites Sanford- Lake Mary by IHG
DoubleTree by Hilton Hotel Orlando East - UCF Area

DoubleTree by Hilton Hotel Orlando East - UCF Area

4 out of 5
12125 High Tech Ave Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $133 per night from Apr 27 to Apr 28
CA $133
CA $150 total
Apr 27 - Apr 28
includes taxes & fees
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,011 reviews)
Staff was super nice always greeted us walking in, perfect location

Reviewed on Apr 20, 2026

Opens in a new windowDoubleTree by Hilton Hotel Orlando East - UCF Area
Grand Bohemian Orlando, Autograph Collection

Grand Bohemian Orlando, Autograph Collection

4.5 out of 5
325 S Orange Ave Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $348 per night from May 3 to May 4
CA $348
CA $391 total
May 3 - May 4
includes taxes & fees
Book a stay at this luxury hotel in Orlando. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Large, clean room with great pool view. Front desk staff were a little aloof and cool. Area around hotel is a little sketchy at night.

Reviewed on Apr 20, 2026

Opens in a new windowGrand Bohemian Orlando, Autograph Collection
DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport

4 out of 5
5555 Hazeltine National Drive Orlando FL
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from May 4 to May 5
CA $173
CA $195 total
May 4 - May 5
includes taxes & fees
Stay at this hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (2,318 reviews)
Very nice hotel and convenient airport parking!

Reviewed on Apr 18, 2026

Opens in a new windowDoubleTree by Hilton Orlando Airport
The Alfond Inn

The Alfond Inn

4 out of 5
300 East New England Avenue Winter Park FL
Fully refundableReserve now, pay when you stay
The price is CA $377 per night from May 18 to May 19
CA $377
CA $463 total
May 18 - May 19
includes taxes & fees
Book a stay at this luxury hotel in Winter Park. Enjoy free WiFi, 2 outdoor pools, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,001 reviews)
Staff friendly. Very convenient location to restaurants and sights. Furnishings seemed quite worn and tired.

Reviewed on Apr 12, 2026

Opens in a new windowThe Alfond Inn
Orlando Marriott Lake Mary

Orlando Marriott Lake Mary

4 out of 5
1501 International Pkwy Lake Mary FL
Fully refundableReserve now, pay when you stay
The price is CA $167 per night from May 3 to May 4
CA $167
CA $191 total
May 3 - May 4
includes taxes & fees
Stay at this hotel in Lake Mary. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (943 reviews)
The room was spacious. The staff was great.

Reviewed on Apr 20, 2026

Opens in a new windowOrlando Marriott Lake Mary
Don't see what you're looking for?
See all available properties in Sanford
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Sanford

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Sanford 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Sanford will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Sanford, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Sanford hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity