Find and compare 5 Star hotels in Santa Cruz

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Featured Santa Cruz 5 Star hotels

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is CA $167 per night from May 29 to May 30
CA $167
CA $167 total
May 29 - May 30
Book a stay at this luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (230 reviews)
Amazing time

Reviewed on Apr 9, 2026

Opens in a new windowMarriott Santa Cruz de la Sierra Hotel
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

5 out of 5
AV ROCA CORONADO 901 Santa Cruz
The price is CA $144 per night from May 27 to May 28
CA $144
CA $144 total
May 27 - May 28
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle ...
9.2/10 Wonderful! (113 reviews)
I was improperly charged for a room that I didn't use. Terrible service from Novotel and Expedia together. I do not recomend them.

Reviewed on May 6, 2026

Opens in a new windowNovotel Santa Cruz De La Sierra
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Santa Cruz

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santa Cruz to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santa Cruz 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santa Cruz before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santa Cruz hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity