Santa Cruz Vacations 2025

Top Santa Cruz hotels deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455, Santa Cruz

Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Patio Design LifeStyle Center and Ventura Mall are located nearby.

Pool

Hot tub

Camino Real Hotel

Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz

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Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz Zoo are located nearby.

Pool

Hot tub

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz

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Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Ventura Mall and Patio Design LifeStyle Center are located nearby.

Pool

Spa

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

San Martin Avenue Esq Street E - E, Santa Cruz

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Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ventura Mall and Patio Design LifeStyle Center are located nearby.

Breakfast included

Parking included

Novotel Santa Cruz De La Sierra

AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz

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Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle Center are located nearby.

Pool

Hot tub

Lido Hotel

Calle 21 de Mayo 527, Santa Cruz

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Stay at this 3-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Arenal Park and Ethno-folkloric Museum are located nearby.

Breakfast included

Parking included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Plaza 24 de Septiembre

5/5(5 reviews)

Learn about the local history of Santa Cruz when you spend time at Plaza 24 de Septiembre. While in the area, you can find time to visit its shops.

San Lorenzo Cathedral

5/5(4 reviews)

Learn about the local history of Santa Cruz when you spend time at San Lorenzo Cathedral. While in the area, you can find time to visit its shops.

Ventura Mall

4.5/5(3 reviews)

During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.

Santa Cruz Vacations

Got your plane ticket locked in and your bags all packed? Read on for a few basic Santa Cruz tips before you go.

If you need some help finding your bearings, La Paz, the national capital, is 340 miles (547 kilometers) to the west. Additionally, La Belgica is 16 miles (26 kilometers) to the north.

Places to visit in Santa Cruz

Want some movie magic? Take in a screening at Cine Center and get caught up in the escapism of the silver screen, bucket of popcorn in hand. Need some more options? From novels to newspapers, Municipal Library has plenty of reading material for eager bookworms. Why not attend a tour and hear about the in-house collections? But there's more. Enjoy a walk on the wild side! Take the whole family to Santa Cruz Zoo and watch the kids' faces come alive as they meet some of the natural marvels of the animal world.

Where do you fly into for Santa Cruz?

Say hello to unique experiences in Santa Cruz. Once you've headed out of El Trompillo Airport (SRZ), the main streets will be just 1 mile (2 kilometers) to the north.

Frequently asked questions

How much are vacation packages to Santa Cruz?

You might be pleasantly surprised — you can vacation in Santa Cruz for a paltry . Here at Travelocity, we save you money and hassle with our amazing vacation packages. With flights, hotels and experiences all available at our one-stop shop, why wait any longer?

How long should my Santa Cruz vacation be?

Most people spend about 4 nights in Santa Cruz, but how long you stay is your call. If you’re hoping to explore all the fantastic things this destination offers, why not hang around another couple of nights?

Where can I get the best vacation package deals for Santa Cruz?

No matter your style, Travelocity can help you score the best Santa Cruz package deal. All you have to do is mix and match from our 400 airlines and 1,000,000 worldwide properties.

Why should I purchase my Santa Cruz vacation bundle via Travelocity?

From amazing destinations to thrilling experiences, we have everything you need to satisfy your wanderlust. Our friendly 24/7 customer support will also ensure you’re taken care of before, during and after your trip. And don’t panic if you notice a better price on your reservation, we’ll match it. That’s our Price Match Guarantee.

Can I save money on my Santa Cruz car rental if I book it with hotels and flights?

Definitely. And our Santa Cruz vacation packages will help you do it. In only a few clicks you can save cash as well as time by combining your bookings. Pick up the keys to your rental car then set your own course. Looking for things to do? Add some tours or experiences to your package and save on those too.

Which airport is best for Santa Cruz?

Flying into Santa Cruz means disembarking at Viru Viru Intl. Airport (VVI). It’s situated 16 kilometers north of the downtown area.

What is there to do in Santa Cruz?

Santa Cruz is brimming with sights to discover, like Ventura Mall and Guembe Biocenter. These renowned attractions are on most visitors’ must-see lists.

Where should I stay when visiting Santa Cruz?

Many people choose to stay at the Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. It’s a great base for your Santa Cruz getaway.