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Hotels near South Central Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $282 per night from Jul 7 to Jul 8
CA $282
CA $394 total
Jul 7 - Jul 8
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
"This hotel is marketed as upscale and luxurious, but my experience was quite the opposite. After arriving late in the evening, around 11:45 PM, I was disappointed to find a room that felt extremely dated and in need of significant renovation. The furnishings and overall condition of the room gave ..."

Reviewed on Jun 21, 2026

Opens in a new windowHotel Zaza Houston Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is CA $234 per night from Jul 6 to Jul 7
CA $234
CA $302 total
Jul 6 - Jul 7
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
"Everyone was welcoming and provided us with great information regarding transport around the city. The restaurant food was delicious and our room was incredibly clean. Absolutely would return."

Reviewed on Jun 21, 2026

Opens in a new windowInterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $190 per night from Jul 5 to Jul 6
CA $190
CA $237 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
"Very well-balanced property, in front of the Red Line of the Monorail, very convenient."

Reviewed on Jun 22, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Jul 12 to Jul 13
CA $121
CA $141 total
Jul 12 - Jul 13
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.
"Great for a one night stay if you are partying in the downtown area."

Reviewed on Jun 16, 2026

Opens in a new windowDowntowner Inns - Houston Downtown
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $228 per night from Jul 5 to Jul 6
CA $228
CA $312 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
"Convenient location to medical area"

Reviewed on Jun 21, 2026

Opens in a new windowHouston Marriott Medical Center/Museum District
Sentral Forme Houston

Sentral Forme Houston

4.5 out of 5
5501 La Branch Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $239 per night from Jul 7 to Jul 8
CA $239
CA $321 total
Jul 7 - Jul 8
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy a 24-hour fitness center, parking (surcharge), and a 24-hour front desk. Popular attractions Toyota Center ...
"This was a strange place. Unlike the way it was advertised, it is primarily an apartment building, not a hotel. Staffing was sparse and there was no place in the building to get something to eat or buy necessities. We were given a fully stocked studio apartment even though we booked a room. Maid ..."

Reviewed on Jun 20, 2026

Opens in a new windowSentral Forme Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $141 per night from Jul 5 to Jul 6
CA $141
CA $166 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
"Nice lobby staff breakfast are so good and the atmosphere was so cool and the bar"

Reviewed on Jun 20, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from Jul 5 to Jul 6
CA $173
CA $203 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
"Would like hot water provided by front dessert for morning coffee. I bring my own coffee but need hot water only."

Reviewed on Jun 18, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Jun 24 to Jun 25
CA $121
CA $142 total
Jun 24 - Jun 25
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
"It’s right by the medical district. There is a train station about 3-4 min away. Breakfast is only coffee, hot water, oatmeal, packaged muffins and cereal bars. We felt the neighborhood was safe. The room was spacious. Plenty of parking available. You have to request the pots and pans at the front ..."

Reviewed on Jun 21, 2026

Opens in a new windowExtended Stay America Suites Houston Med Ctr Braeswood Bl
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About South Central Houston Hotels

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Recent South Central Houston hotel reviews by fellow wanderers

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Very well-balanced property, in front of the Red Line of the Monorail, very convenient."
A verified traveller stayed at The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District

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