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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
3-star hotel near Mayo Clinic Florida

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Photo gallery for Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Lobby
Reception
Exterior
Bar (on property)
Reception

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Bar
  • Housekeeping
  • Laundry
  • Kitchen

Explore the area

View in a map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
  • Place, Mayo Clinic Florida
    ‪17 min walk‬
  • Place, St. Johns Town Center
    ‪7 min drive‬
  • Place, Mayport Naval Station
    ‪17 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪33 min drive‬

Room options

View all photos for Studio, 1 King Bed with Sofa bed, Corner

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 50 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner

Studio Suite, 1 Bedroom, Corner

Studio Suite, 1 Bedroom, Corner

10.0 out of 10
Exceptional
(3 reviews)
  • 60 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed

Fridge, microwave, stovetop, dishwasher

Studio Suite, 1 King Bed with Sofa bed

9.6 out of 10
Exceptional
(81 reviews)
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom

Studio Suite, 1 Bedroom | Living room

Studio Suite, 1 Bedroom

9.8 out of 10
Exceptional
(17 reviews)
  • 52 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

8.0 out of 10
Very good
(4 reviews)
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

  • 38 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 52 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 50 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 60 sq m
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

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About the area

Jacksonville

Isle of Palms stay.With a stay at this Isle of Palms hotel, you'll be within 2 miles (3 km) of Mayo Clinic Florida and 6 miles (10 km) of Windsor Commons Shopping Center. Windsor Parke Golf Club and Adventure Landing are also within 6 miles (10 km).

What's nearby

  • Mayo Clinic Florida - 17 min walk - 1.5 km
  • University of North Florida - 5 min drive - 9.0 km
  • St. Johns Town Center - 7 min drive - 11.5 km
  • Mayport Naval Station - 17 min drive - 18.2 km
  • Jacksonville Naval Air Station - 29 min drive - 47.7 km

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 13 min drive

Restaurants

  • ‪Culver’s - ‬4 min drive
  • ‪M Brothers at Mayo - ‬18 min walk
  • ‪Starbucks - ‬4 min drive
  • ‪Circle K - ‬10 min walk
  • ‪Bundy Cafe & Atrium - ‬18 min walk

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3-star hotel near Mayo Clinic Florida
Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers its guests an outdoor pool and a 24-hour fitness center. You can enjoy a drink at one of the bars, which include a poolside bar and a bar/lounge. Free breakfast is served daily. A computer station is on site and WiFi is free in public spaces.

A 24-hour business center, 2 meeting rooms, and coworking spaces are available. Event space at this hotel measures 2678 square feet (249 square meters) and includes conference space. Barbecue grills, multilingual staff, and a garden are also featured at the business-friendly Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Self parking is free.

This 3-star Jacksonville hotel is smoke free.

  • 1 building
  • 155 guestrooms or units
  • 7 levels
  • 2678 sq ft of conference space
  • 249 sq m of conference space
  • Built in 2020
  • Buffet breakfast (free)
  • Poolside lounge chairs
  • Business center (24 hours)
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Staff is multilingual
  • Storage area for luggage
  • Front-desk safe
  • Concierge
  • Grocery service (free)
  • Wedding services available
  • Convenience store
  • Garden
  • BBQ grill(s)
  • Outdoor picnic space
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Elevator
  • No smoking on site
  • Water dispenser
  • Bar or lounge
  • Bar by the pool
Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers 155 air-conditioned accommodations with laptop-compatible safes and coffee/tea makers. Accommodations offer separate sitting areas. 55-inch Smart televisions come with premium cable channels and Netflix. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and separate dining areas. Bathrooms include bathtubs or showers, complimentary toiletries, and hair dryers.

This Jacksonville hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered daily and change of bedsheets can be requested. Housekeeping is provided on request.

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Property amenities

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical outlets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

Room amenities

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Stovetop
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Energy-saving switches in guestrooms
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 6:00 AM
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 150 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 40 lbs per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Deposit: USD 125 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 150 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, and Diners Club. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards in each accommodation. Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

We should mention

  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 353 out of 446 reviews
Rating 8 - Good. 65 out of 446 reviews
Rating 6 - Okay. 12 out of 446 reviews
Rating 4 - Poor. 12 out of 446 reviews
Rating 2 - Terrible. 4 out of 446 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Bonnie, Ormond Beach

Liked: Cleanliness, staff & service, property conditions & facilities
Very nice hotel - clean, quiet and the most convenient to the Mayo Clinic.
Stayed 1 night in Nov 2025

10/10 Excellent

Tyler

Stayed 2 nights in Sep 2025

8/10 Good

TASHA D.

Business traveller, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This property is closed to the Mayo Clinic
Stayed 1 night in Aug 2025

10/10 Excellent

Gary

Travelled with family, Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great facility to stay.
Stayed 1 night in Sep 2025

10/10 Excellent

DANIEL

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

8/10 Good

Gerard

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Often stay there. Great value. The only area of friction is how they do room service. You have to call the front desk who takes your order. They pass it on to the restaurant. Multiple times things get mixed up or forgotten. A direct line to the restaurant would be a better solution. Also a menu in the room or accessible through the tv or smartphone would be helpful. If you forget to ask the front desk for a menu then you are on your own. I will say the food is very good.
Stayed 1 night in Aug 2025

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Gerald

Business traveller, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room and bedroom was very well done
Stayed 2 nights in Aug 2025

10/10 Excellent

Tyeisha

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Terrific Stay 10/10

I had an amazing stay. The staff was friendly, the room was spotless. All the attractions were minutes away. The hotel felt like home away from home. Highly recommended. I will be back.
Stayed 2 nights in Aug 2025

10/10 Excellent

Joseph

Stayed 3 nights in Aug 2025

10/10 Excellent

james

Stayed 3 nights in Apr 2025

10/10 Excellent

james

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent place to Stay!!
Stayed 1 night in Jul 2025

10/10 Excellent

KENNETH

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property was clean, fairly new, comfortable, and the staff was friendly and helpful.
Stayed 2 nights in Jul 2025

10/10 Excellent

Lauren

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 17 nights in Jun 2025

10/10 Excellent

Barris

Liked: Cleanliness, staff & service, property conditions & facilities
Great
Stayed 2 nights in Jul 2025

10/10 Excellent

Amit

Travelled with family
Liked: Cleanliness, amenities, property conditions & facilities
We drove from WV and stopped after a long drive. The room was comfortable and check-in / checkout was efficient. Breakfast was good as well.
Stayed 2 nights in Jul 2025

10/10 Excellent

Rabindra, Wesley Chapel

Stayed 2 nights in Jul 2025

10/10 Excellent

Jeremy

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jul 2025

10/10 Excellent

Jacob

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Leah

Liked: Cleanliness, amenities, property conditions & facilities
Loved very
Stayed 2 nights in Jul 2025

10/10 Excellent

Verified traveller

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jun 2025

10/10 Excellent

SHERICE

Travelled with pets, Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Very nice. About 3.5 miles from the beach. Breakfast was amazing especially loved their coffee.
Stayed 2 nights in Jul 2025

10/10 Excellent

Jonah-Nehemiah

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Jul 2025

10/10 Excellent

Said

Stayed 1 night in Jun 2025

10/10 Excellent

glyn

Liked: Cleanliness, amenities, property conditions & facilities
Stayed 4 nights in Jun 2025