Photo by Ashish Joshi

Book a hotel near Mission San Luis Obispo de Tolosa, Downtown San Luis Obispo

Start date: Check-in selected.
To Date
End date: Check-out

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Hotels near Mission San Luis Obispo de Tolosa

SLO Brew Lofts

SLO Brew Lofts

4 out of 5
738 Higuera San Luis Obispo CA
0.15 km from Mission San Luis Obispo de Tolosa
Get rates
Stay at this condo in San Luis Obispo. Enjoy free WiFi, laundry facilities, and cable TV channels. Popular attractions Bubblegum Alley and Downtown SLO Farmers' Market are located nearby.
Kitchen
Pet-friendly
Hotel San Luis Obispo

Hotel San Luis Obispo

4.5 out of 5
877 Palm Street San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
0.16 km from Mission San Luis Obispo de Tolosa
The price is CA $450 per night
CA $450
CA $511 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this luxury hotel in San Luis Obispo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Ah Louis Store and San Luis Obispo County Library are located nearby.
Pool
Spa
HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection

4 out of 5
1125 Garden St San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
0.18 km from Mission San Luis Obispo de Tolosa
The price is CA $312 per night
CA $312
CA $402 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this spa hotel in San Luis Obispo. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bubblegum Alley and Downtown SLO Farmers' Market are located nearby.
Pool
Spa
Granada Hotel & Bistro

Granada Hotel & Bistro

4 out of 5
1126 Morro St. San Luis Obispo CA
0.28 km from Mission San Luis Obispo de Tolosa
The price is CA $248 per night
CA $248
CA $283 total
Jan 26 - Jan 27, 2026
includes taxes & fees
Stay at this hotel in San Luis Obispo. Enjoy free WiFi, room service, and parking (surcharge). Our guests praise the bar and the helpful staff in our reviews. Popular attractions Fremont Theater and Downtown SLO Farmers' Market are located nearby.
Free WiFi
Restaurant
Garden Street Inn, A Kirkwood Collection Hotel

Garden Street Inn, A Kirkwood Collection Hotel

4 out of 5
1212 Garden St San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
0.28 km from Mission San Luis Obispo de Tolosa
The price is CA $212 per night
CA $212
CA $241 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Stay at this B&B in San Luis Obispo. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Downtown SLO Farmers' Market and Bubblegum Alley are located nearby.
Breakfast included
Free WiFi
Downtown SLO Inn - San Luis Obispo

Downtown SLO Inn - San Luis Obispo

2 out of 5
950 Olive Street San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
0.67 km from Mission San Luis Obispo de Tolosa
Get rates
Stay at this motel in San Luis Obispo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santa Rosa Park and San Luis Obispo County Library are located nearby.
Parking included
Free WiFi
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

2.5 out of 5
345 Marsh St San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
0.71 km from Mission San Luis Obispo de Tolosa
The price is CA $94 per night
CA $94
CA $107 total
Jan 28 - Jan 29, 2026
includes taxes & fees
Stay at this motel in San Luis Obispo. Enjoy free WiFi, free parking, and premium TV channels. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cerro San Luis Obispo and San Luis Obispo Children's Museum are located nearby.
Parking included
Free WiFi
Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

3 out of 5
1631 Monterey St San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
1.26 km from Mission San Luis Obispo de Tolosa
The price is CA $165 per night
CA $165
CA $222 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Luis Obispo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Dallidet Adobe and Gardens and Fremont Theater are located nearby.
Pool
Hot tub
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3 out of 5
1845 Monterey St. San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
1.53 km from Mission San Luis Obispo de Tolosa
The price is CA $155 per night
CA $155
CA $176 total
Jan 25 - Jan 26, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Luis Obispo. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Dallidet Adobe and Gardens and Santa Rosa Park are located nearby.
Pool
Hot tub
Sands Inn & Suites

Sands Inn & Suites

2.5 out of 5
1930 Monterey Street San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
1.6 km from Mission San Luis Obispo de Tolosa
Get rates
Book a stay at this business-friendly motel in San Luis Obispo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Dallidet Adobe and Gardens and Santa Rosa Park are located nearby.
Pool
Breakfast included
Apple Farm

Apple Farm

3.5 out of 5
2015 Monterey St San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
1.73 km from Mission San Luis Obispo de Tolosa
Get rates
Book a stay at this business-friendly hotel in San Luis Obispo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Performing Arts Center and Robert A. Mott Athletics Center are located nearby.
Pool
Hot tub
Madonna Inn

Madonna Inn

3.5 out of 5
100 Madonna Road San Luis Obispo CA
Free cancellation
Reserve now, pay when you stay
1.73 km from Mission San Luis Obispo de Tolosa
The price is CA $204 per night
CA $204
CA $278 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this spa hotel in San Luis Obispo. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Madonna Plaza Shopping Center and Cerro San Luis Obispo are located nearby.
Pool
Hot tub
Don't see what you're looking for?
See all available properties in Mission San Luis Obispo de Tolosa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About Mission San Luis Obispo de Tolosa Hotels Near Attractions

Do you have a full travel itinerary while visiting Mission San Luis Obispo de Tolosa? Don't waste your time commuting too far from Mission San Luis Obispo de Tolosa area attractions.

Mission San Luis Obispo de Tolosa hotels essential information

Accommodation
1,086 hotels
Lowest Price
CA $107
Highest Price
CA $511
Popular hotels
Quality Suites Downtown San Luis Obispo, La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown, Hotel San Luis Obispo, Madonna Inn, Apple Farm, Avenue Inn Downtown San Luis Obispo, Garden Street Inn, A Kirkwood Collection Hotel, HOTEL CERRO, Autograph Collection, Granada Hotel & Bistro, SLO Brew Lofts, Sands Inn & Suites, Downtown SLO Inn - San Luis Obispo

Recent Mission San Luis Obispo de Tolosa hotel reviews by fellow wanderers

Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

5 out of 5
Posted 20 hours ago
Travelocity Verified Review
"Very convenient place, clean, walking distance to all attractions and people are very nice and professional, very happy with our experience."
A verified traveller stayed at Avenue Inn Downtown San Luis Obispo
Avenue Inn Downtown San Luis Obispo

Types of hotels

Hotels near…

Areas of Mission San Luis Obispo de Tolosa