Search Panama City luxury spa hotels

Our top choices for a great stay

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
The price is CA $515 per night from Feb 23 to Feb 24
CA $515
CA $567 total
Feb 23 - Feb 24
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (588 reviews)
Opens in a new windowSofitel Legend Casco Viejo, Panama City
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 out of 5
The price is CA $545 per night from Mar 2 to Mar 3
CA $545
CA $599 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (267 reviews)
Opens in a new windowHotel La Compañía Casco Antiguo
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
The price is CA $367 per night from Mar 7 to Mar 8
CA $367
CA $403 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (664 reviews)
Opens in a new windowThe Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 out of 5
The price is CA $224 per night from Mar 7 to Mar 8
CA $224
CA $246 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida ...
9.6/10 Exceptional! (195 reviews)
Opens in a new windowHyatt Regency Panama City
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
The price is CA $251 per night from Mar 16 to Mar 17
CA $251
CA $276 total
Mar 16 - Mar 17
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,007 reviews)
Opens in a new windowBristol Panama, a Registry Collection Hotel
Hilton Panama

Hilton Panama

5 out of 5
The price is CA $299 per night from Mar 8 to Mar 9
CA $299
CA $329 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,001 reviews)
Opens in a new windowHilton Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
The price is CA $300 per night from Mar 7 to Mar 8
CA $300
CA $330 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Opens in a new windowWaldorf Astoria Panama
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 out of 5
The price is CA $225 per night from Mar 3 to Mar 4
CA $225
CA $247 total
Mar 3 - Mar 4
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,009 reviews)
Opens in a new windowSortis Hotel, Spa & Casino, Autograph Collection by Marriott
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
The price is CA $336 per night from Mar 7 to Mar 8
CA $336
CA $369 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,413 reviews)
Opens in a new windowMegapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.