Search Panama City luxury spa hotels
Our top choices for a great stay
Hyatt Regency Panama City
The price is CA $209 per night from Sep 14 to Sep 15
CA $209
CA $230 total
Sep 14 - Sep 15
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and ...
10/10 Exceptional! (56 reviews)
Sofitel Legend Casco Viejo, Panama City
The price is CA $404 per night from Sep 3 to Sep 4
CA $404
CA $445 total
Sep 3 - Sep 4
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (493 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The price is CA $305 per night from Sep 14 to Sep 15
CA $305
CA $335 total
Sep 14 - Sep 15
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (599 reviews)
Hotel La Compania, in the Unbound Collection by Hyatt
The price is CA $364 per night from Sep 1 to Sep 2
CA $364
CA $400 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (228 reviews)
Bristol Panama, a Registry Collection Hotel
The price is CA $302 per night from Sep 23 to Sep 24
CA $302
CA $332 total
Sep 23 - Sep 24
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,000 reviews)
Hilton Panama
The price is CA $293 per night from Sep 20 to Sep 21
CA $293
CA $322 total
Sep 20 - Sep 21
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,001 reviews)
Waldorf Astoria Panama
The price is CA $304 per night from Sep 20 to Sep 21
CA $304
CA $335 total
Sep 20 - Sep 21
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
The price is CA $220 per night from Aug 30 to Aug 31
CA $220
CA $242 total
Aug 30 - Aug 31
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (984 reviews)
Megapolis Hotel Panamá
The price is CA $176 per night from Aug 30 to Aug 31
CA $176
CA $193 total
Aug 30 - Aug 31
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,036 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.