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Our top choices for a great stay

Brand New 6BR/6BA Luxury Home, 20 min to Clemson. Flat lot/firepit/pool table!

Brand New 6BR/6BA Luxury Home, 20 min to Clemson. Flat lot/firepit/pool table!

Stay at this vacation home in Seneca. Enjoy free WiFi, 8 outdoor pickleball courts, and a garden. Popular attractions Lake Keowee and High Falls County Park ...
10/10 Exceptional! (21 reviews)
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Brand New 6BR/6BA Luxury Home, 20 min to Clemson. Flat lot/firepit/pool table!
New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

Stay at this vacation home in Seneca. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions South Cove Park and Keowee Reservoir are located ...
10/10 Exceptional! (43 reviews)
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New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson

Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson

Stay at this vacation home in Seneca. Enjoy free WiFi, laundry facilities, and patios. Popular attractions South Cove Park and Keowee Reservoir are located ...
10/10 Exceptional! (47 reviews)
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Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Book a stay at this family-friendly vacation home in Seneca. Enjoy free WiFi, a garden, and laundry facilities. Our guests praise the helpful staff in our reviews. ...
9.8/10 Exceptional! (142 reviews)
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6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

Stay at this vacation home in Seneca. Enjoy free WiFi, laundry facilities, and a pool table. Popular attractions Friendship Recreaction Area and Townville Landing ...
9.8/10 Exceptional! (47 reviews)
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Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Horses, Big Sky, Boat and Horse Trailer Parking, Acreage, Tiny Home

Horses, Big Sky, Boat and Horse Trailer Parking, Acreage, Tiny Home

Stay at this vacation home in Seneca. Enjoy an in-room coffeemaker and air conditioning. Popular attractions Friendship Recreaction Area and Townville Landing ...
9.8/10 Exceptional! (63 reviews)
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Horses, Big Sky, Boat and Horse Trailer Parking, Acreage, Tiny Home
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!

Lake Hartwell Home w/ Dock < 10 Miles to Clemson!

Stay at this vacation home in Seneca. Enjoy a garden, laundry facilities, and patios. Popular attractions Friendship Recreaction Area and Townville Landing are ...
9.6/10 Exceptional! (55 reviews)
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Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
Family getaway on lake near Clemson campus

Family getaway on lake near Clemson campus

Stay at this vacation home in Seneca. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Keowee and High Falls County Park are located ...
9.2/10 Wonderful! (47 reviews)
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Family getaway on lake near Clemson campus
Roomy and gorgeous home on Lake Keowee with hot tub!

Roomy and gorgeous home on Lake Keowee with hot tub!

Stay at this vacation home in Seneca. Enjoy free WiFi, laundry facilities, and a pool table. Popular attractions South Cove Park and Golden Corner Plaza are ...
9/10 Wonderful! (8 reviews)
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Roomy and gorgeous home on Lake Keowee with hot tub!
Horses, Big Sky, Tiny Home and Boat and Horse Trailer Parking

Horses, Big Sky, Tiny Home and Boat and Horse Trailer Parking

Stay at this vacation home in Seneca. Enjoy an in-room coffeemaker and air conditioning. Popular attractions Friendship Recreaction Area and Townville Landing ...
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Horses, Big Sky, Tiny Home and Boat and Horse Trailer Parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.