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Featured Santorini 4 Star hotels

Hotel Daedalus

Hotel Daedalus

4 out of 5
Fira Town Santorini Santorini Island
Fully refundableReserve now, pay when you stay
The price is CA $223 per night from Jul 2 to Jul 3
CA $223
CA $270 total
Jul 2 - Jul 3
includes taxes & fees
Book a stay at this business-friendly hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Athinios Port and Santorini ...
8.6/10 Excellent! (180 reviews)
"Friendly stuff great location"

Reviewed on Jun 13, 2026

Opens in a new windowHotel Daedalus
Santorini Palace

Santorini Palace

4 out of 5
Fira town Santorini Santorini Island
The price is CA $214 per night from Jul 5 to Jul 6
CA $214
CA $260 total
Jul 5 - Jul 6
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (791 reviews)
"Nice hotel in a decent location in Santorini thpugh there is a very steep road to get into the hotel. The breakfast was not great, pretty limited food selection. The pool was packed in the morning thus we were not able to find available chairs, have to sit at the bar chairs. I would give it 3.5 ..."

Reviewed on Jun 26, 2026

Opens in a new windowSantorini Palace
El Greco Resort

El Greco Resort

4 out of 5
Fira Santorini Santorini Island
Fully refundableReserve now, pay when you stay
The price is CA $236 per night from Jul 4 to Jul 5
CA $236
CA $284 total
Jul 4 - Jul 5
includes taxes & fees
Book a stay at this beach hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (563 reviews)
"Amazing stay, and beautiful hotel, great breakfast with lots of options! 3 different pools! 10/10!"

Reviewed on Jun 30, 2026

Opens in a new windowEl Greco Resort
Anamar Santorini

Anamar Santorini

4 out of 5
Monolithos Santorini Santorini
Stay at this hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Kamari Beach and Athinios Port are located nearby.
7.2/10 Good! (56 reviews)
"Very nice and welcoming staff Breakfast was great"

Reviewed on Nov 24, 2024

Opens in a new windowAnamar Santorini
Hermes Hotel

Hermes Hotel

4 out of 5
Ermis Street, Kamari Santorini Santorini Island
The price is CA $161 per night from Jul 13 to Jul 14
CA $161
CA $199 total
Jul 13 - Jul 14
includes taxes & fees
Book a stay at this business-friendly hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (203 reviews)
"The staffs are lovely. Room is cleaning every day! Fresh food and very close to the beach. Best beach Kamari. Recommend highly."

Reviewed on Jun 27, 2026

Opens in a new windowHermes Hotel
Villa Manos

Villa Manos

4 out of 5
Karterados Santorini Santorini Island
The price is CA $108 per night from Jul 2 to Jul 3
CA $108
CA $139 total
Jul 2 - Jul 3
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (347 reviews)
"Very, very friendly staff. Very accommodating. Very welcoming."

Reviewed on May 20, 2026

Opens in a new windowVilla Manos
Afroditi Venus Beach Resort

Afroditi Venus Beach Resort

4 out of 5
Kamari Beach Santorini Santorini Island
The price is CA $165 per night from Jul 17 to Jul 18
CA $165
CA $203 total
Jul 17 - Jul 18
includes taxes & fees
Book a stay at this beach hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (251 reviews)
"Lovely clean hotel, however be aware steps are everywhere, would not recommend for disabled travellers who have difficulty with steps. Do not expect WiFi, hotel offers free WiFi however its so slow it sends u back to 1980s. 1 to 2 mps is all I could get, so data use was recalled."

Reviewed on Jun 17, 2026

Opens in a new windowAfroditi Venus Beach Resort
Nikos Hotel

Nikos Hotel

4 out of 5
Karterados Santorini
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Jul 27 to Jul 28
CA $139
CA $175 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (46 reviews)
"I stayed 3 nights in a triple room in a newly renovated part of the hotel. Clean sheets, blankets and towels - new bathroom, huge terrace, good A/C. For the amazing price without breakfast I can’t complain. The pool was immaculate - no one uses it but a lovely large cool pool with a jacuzzi and nice ..."

Reviewed on Jun 12, 2026

Opens in a new windowNikos Hotel
Esperas Santorini

Esperas Santorini

4 out of 5
Oia Santorini
The price is CA $404 per night from Jul 17 to Jul 18
CA $404
CA $475 total
Jul 17 - Jul 18
includes taxes & fees
Book a stay at this luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowEsperas Santorini
Cliff Side Suites

Cliff Side Suites

4 out of 5
Firostefani Santorini Santorini Island
The price is CA $341 per night from Jul 2 to Jul 3
CA $341
CA $404 total
Jul 2 - Jul 3
includes taxes & fees
Stay at this hotel in Santorini. Enjoy free WiFi, room service, and a 24-hour front desk. Popular attractions Santorini Caldera and Athinios Port are located ...
9.2/10 Wonderful! (129 reviews)
"Best bang for the buck on Santorini. Staff was amazing and the property was in a perfect location. If I booked again, it would definitely be here."

Reviewed on Jun 18, 2026

Opens in a new windowCliff Side Suites
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4 Star Hotels Santorini

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Santorini 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Santorini will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Santorini, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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