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Featured Syros 5 Star hotels

CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS

5 out of 5
TAGOO MYKONOS Mykonos
The price is CA $1,245 per night from Jun 7 to Jun 8
CA $1,245
CA $1,441 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Mykonos Old Port and Mykonos New Port ...
9.2/10 Wonderful! (38 reviews)
"The staff were incredible! The location was probably the best in town and the room that I stayed in was gorgeous. I don’t have a single complaint or feedback - this property was perfect. 10/10"

Reviewed on Jun 1, 2026

Opens in a new windowCAVO TAGOO MYKONOS
Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux

5 out of 5
Platis Gialos Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $362 per night from Jun 4 to Jun 5
CA $362
CA $436 total
Jun 4 - Jun 5
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (730 reviews)
"If only they had a heated pool, otherwise place was nice. Food and water were pretty expensive"

Reviewed on Jun 1, 2026

Opens in a new windowMyconian Ambassador Hotel Relais & Chateaux
Palladium Hotel

Palladium Hotel

5 out of 5
Plati Yialos Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $318 per night from Jun 3 to Jun 4
CA $318
CA $386 total
Jun 3 - Jun 4
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9.8/10 Exceptional! (839 reviews)
"Well kept, very clean property. Staff was excellent!"

Reviewed on Jun 2, 2026

Opens in a new windowPalladium Hotel
Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux

5 out of 5
Main Street, Mykonos Town Mykonos
Fully refundableReserve now, pay when you stay
The price is CA $585 per night from Jun 16 to Jun 17
CA $585
CA $690 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (554 reviews)
"The staff at Korali are beyond excellent. Miko, Georgia, Iola and especially Georgi at the restaurants are absolutely out of this world! We cancelled reservations to eat at their restaurants and regretted almost every meal we had outside of this hotel. Georgi is brilliant when it comes to wine pairing ..."

Reviewed on Jun 1, 2026

Opens in a new windowMyconian Korali Relais & Chateaux
Tropicana Suites & Villas

Tropicana Suites & Villas

5 out of 5
Paradise Beach Mykonos
The price is CA $649 per night from Jul 2 to Jul 3
CA $649
CA $763 total
Jul 2 - Jul 3
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
Opens in a new windowTropicana Suites & Villas
Nissaki Boutique Hotel

Nissaki Boutique Hotel

5 out of 5
Platis Gialos Beach Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $522 per night from Jun 4 to Jun 5
CA $522
CA $619 total
Jun 4 - Jun 5
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.8/10 Exceptional! (866 reviews)
"Very personal service with great water views."

Reviewed on Jun 1, 2026

Opens in a new windowNissaki Boutique Hotel
Semeli Hotel

Semeli Hotel

5 out of 5
Mykonos Town Mykonos Mykonos Island
The price is CA $464 per night from Jun 23 to Jun 24
CA $464
CA $552 total
Jun 23 - Jun 24
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (587 reviews)
"The Semeli is a beautiful hotel and exactly what you’d hope for in Mykonos. The property is gorgeous, the rooms are great, and the location makes it easy to enjoy everything the island has to offer. But what really made this stay special was the staff. You can build a beautiful hotel, but it’s the ..."

Reviewed on May 30, 2026

Opens in a new windowSemeli Hotel
Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa

5 out of 5
Aghios Ioannis Beach Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $322 per night from Jun 3 to Jun 4
CA $322
CA $391 total
Jun 3 - Jun 4
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (585 reviews)
"Very clean . Great location . Staff not very helpful ."

Reviewed on May 27, 2026

Opens in a new windowSaint John Hotel Villas & Spa
Bill&Coo Mykonos

Bill&Coo Mykonos

5 out of 5
Megali Ammos Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $930 per night from Jun 14 to Jun 15
CA $930
CA $1,084 total
Jun 14 - Jun 15
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mykonos Old Port and Mykonos New Port are ...
9.8/10 Exceptional! (191 reviews)
"Best breakfast I’ve had at any hotel and an incredible in house bakery The staff especially Dimitri are outstanding that’s why we go back every year."

Reviewed on May 29, 2026

Opens in a new windowBill&Coo Mykonos
Mykonos Blu, A Grecotel Resort to Live

Mykonos Blu, A Grecotel Resort to Live

5 out of 5
Psarou Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $604 per night from Jun 8 to Jun 9
CA $604
CA $712 total
Jun 8 - Jun 9
includes taxes & fees
Book a stay at this luxury hotel in Mykonos. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (308 reviews)
"Five stars on everything"

Reviewed on Jun 1, 2026

Opens in a new windowMykonos Blu, A Grecotel Resort to Live
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Five Star Hotels in Syros

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Syros to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Syros 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Syros before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Syros hotel reviews by fellow wanderers