Book Exclusive De Soto Vacation Packages

Choose one or more items to build your trip:

De Soto flight + hotel packages

Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was CA $915, price is now CA $782 per person
CA $782
per person
Sep 11 - Sep 13
found 24 hours ago
Roundtrip flight included
Detroit (DTW) to St. Louis (STL)
Book a stay at this boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $2,093, price is now CA $1,309 per person
CA $1,309
per person
Aug 11 - Aug 16
found 9 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Six Flags St. Louis and Skid Row are located nearby.
Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

3 out of 5
Price was CA $1,584, price is now CA $1,224 per person
CA $1,224
per person
Aug 11 - Aug 16
found 9 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
Book a stay at this business-friendly hotel in Town and Country. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Saint Louis Galleria Mall and American Kennel Club Museum of the Dog are located nearby.
Landing Amazing 1bd, Yoga Studio, Gym

Landing Amazing 1bd, Yoga Studio, Gym

3 out of 5
DeBaliviere Place
Price was CA $1,317, price is now CA $1,144 per person
CA $1,144
per person
Sep 11 - Sep 13
found 24 hours ago
Roundtrip flight included
Detroit (DTW) to St. Louis (STL)
Stay at this apartment in St. Louis. Enjoy an outdoor pool, a fitness center, and parking (surcharge). Popular attractions Forest Park and St. Louis Zoo are located nearby.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Price was CA $1,303, price is now CA $1,142 per person
CA $1,142
per person
Aug 11 - Aug 16
found 9 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions The J - Chesterfield Gym & Fitness Center and Topgolf are located nearby.

Top De Soto hotels deals

Secluded cabin on private property

Secluded cabin on private property

De Soto MO
Get rates
Stay at this cabin in De Soto. Enjoy free WiFi, a garden, and laundry facilities. Popular attraction Washington State Park is located nearby.
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO
The price is CA $202 per night
CA $202
CA $386 total
Jul 10 - Jul 11
includes taxes & fees
Stay at this cabin in De Soto. Enjoy a garden, laundry facilities, and patios. Popular attractions Eastside Community Park and Ritcher Park are located nearby.
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln Arnold MO
Free cancellation
Reserve now, pay when you stay
The price is CA $128 per night
CA $128
CA $148 total
Jul 14 - Jul 15
includes taxes & fees
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Arnold Historical Society & Museum and BounceU of St. Louis are located nearby.
Pool
Breakfast included
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
Free cancellation
Reserve now, pay when you stay
The price is CA $85 per night
CA $85
CA $93 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wilson Rozier Park and Veterans Park are located nearby.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2.5 out of 5
7555 State Hwy Y French Village MO
The price is CA $132 per night
CA $132
CA $203 total
Aug 5 - Aug 6
includes taxes & fees
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3 out of 5
3800 State Rt 141 Arnold MO
Free cancellation
Reserve now, pay when you stay
The price is CA $179 per night
CA $179
CA $207 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Arnold Historical Society & Museum and BounceU of St. Louis are located nearby.
Don't see what you're looking for?
See all available properties in De Soto
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular De Soto attractions

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?
See properties

De Soto Vacations

Experiencing the real essence of De Soto starts with researching a few basic facts. Are you ready to find out just where this unique destination is and what attractions you should explore?

You can find it 12 miles (19 kilometers) from Bonne Terre and 12 miles (19 kilometers) away from Festus.

Love meeting the locals when you're on vacation? This corner of Missouri has a population of around 6,000 people.

Places to visit in De Soto

Want to alleviate the stress of your busy, urban life? Drink in the fresh air as you take off on an adventure through St. Francois State Park. Want some more ideas? Are you looking to relieve the stress of your busy, urban life? Savor the fresh air as you embark on an adventure through Washington State Park.

Where do you fly into for De Soto?

Bags packed and passport at the ready? Excellent — hop on the plane to Spirit of St. Louis Airport (SUS). Once you hit the runway, you'll be just 40 miles (64 kilometers) from the main streets of De Soto.

Frequently asked questions

How much are vacation packages to De Soto?
Your travel daydreams can become a reality in De Soto from just CA $782. Our package deals include flights and hotels, so organizing your itinerary will be a piece of cake. The only thing you'll have to concentrate on is getting out there and having a great time.
How long should my De Soto vacation be?
Many people choose to spend about 2 nights in De Soto, but how long you stay is your call. If you want to check out all the fantastic things this place offers, why not hang around a while longer?
Where can I get the best vacation package deals for De Soto?
Find your dream escape at Travelocity. With access to 400 airline partners and a whopping 1,000,000 hotels around the world, selecting the perfect De Soto package deal couldn't be easier.
Why should I book my De Soto vacation package via Travelocity?
From enticing destinations to fun experiences, we have everything you need to satisfy your wanderlust. Our 24/7 support will also make sure you're being taken care of before, during and after your vacation. And don't stress if you spot a lower price on your booking, we'll match it. That's our Price Match Guarantee.
Can I save money on my De Soto car rental if I bundle it with a hotel or flight?
Combining your flight, hotel and car into a De Soto vacation package is a surefire way to land the best prices. Plus, having your own car rental gives you absolute freedom to find your way to all the landmarks you're hoping to check out. Sitting 64 kilometers away from De Soto, Busch Stadium is one place that should have a place on your itinerary. Fasten your seat belt and make a day trip of it.
Which airport is best for De Soto?
Flying into De Soto will see you landing at Lambert-St. Louis Intl. Airport (STL). It's roughly 72 kilometers north of the downtown area.
What is there to do in De Soto?
Victoria Glaces Conservation Area Trailhead deserves a spot on your travel itinerary. After you've checked off this well-known attraction, simply roam the streets of De Soto and learn what really makes this cool destination tick.
Where should I stay when visiting De Soto?
Many travelers choose to check in to the Holiday Inn Club Vacations Timber Creek Resort At De Soto. It's a great base for your De Soto getaway.

Photos of local treasures

Browse De Soto vacation photos for more inspiration

A blue kayak on calm river water with trees and rocky cliffs in the background.