
Book Exclusive De Soto Vacation Packages

De Soto flight + hotel packages
Price found within the past 48 hours. Click for updated prices.

Hilton Garden Inn Chesterfield
Price was CA $1,130, price is now CA $870 per person
CA $870
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions The J - Chesterfield Gym & Fitness Center and Topgolf are located nearby.

The Knight Center at Washington University
Price was CA $1,247, price is now CA $959 per person
CA $959
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
Stay at this hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions St. Louis Union Station and St. Louis Zoo are located nearby.

Hampton Inn By Hilton St Louis Airport
Woodson Terrace
Price was CA $1,146, price is now CA $884 per person
CA $884
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
Stay at this hotel in St. Louis. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Payne-Gentry Historical House and Blanche M. Touhill Performing Arts Center are located nearby.

Marriott St. Louis West
Price was CA $1,225, price is now CA $948 per person
CA $948
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Bellerive Country Club and Myseum are located nearby.

Hollywood Casino & Hotel St. Louis
Price was CA $1,226, price is now CA $970 per person
CA $970
per person
Jan 14 - Jan 19
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby.
Top De Soto hotels deals

82 Acre Hobby Farm with Lincoln Log Cabin
De Soto MO
The price is CA $207 per night
CA $207
CA $379 total
Jan 12 - Jan 13, 2026
includes taxes & fees
Stay at this cabin in De Soto. Enjoy a garden, laundry facilities, and patios. Popular attractions Eastside Community Park and Ritcher Park are located nearby.
Kitchen
Washer

Secluded cabin on private property
De Soto MO
Stay at this cabin in De Soto. Enjoy free WiFi, a garden, and laundry facilities. Popular attraction Washington State Park is located nearby.
Kitchen
Washer

Pear Tree Inn St. Louis Arnold
1201 Drury Ln Arnold MO
Free cancellation
Reserve now, pay when you stay
The price is CA $124 per night
CA $124
CA $143 total
Dec 17 - Dec 18
includes taxes & fees
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Arnold Historical Society & Museum and BounceU of St. Louis are located nearby.
Pool
Breakfast included

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free cancellation
Reserve now, pay when you stay
The price is CA $74 per night
CA $74
CA $84 total
Dec 21 - Dec 22
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wilson Rozier Park and Veterans Park are located nearby.
Pool
Breakfast included

Drury Inn & Suites St. Louis Arnold
3800 State Rt 141 Arnold MO
Free cancellation
Reserve now, pay when you stay
The price is CA $169 per night
CA $169
CA $196 total
Dec 17 - Dec 18
includes taxes & fees
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Arnold Historical Society & Museum and BounceU of St. Louis are located nearby.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
Free cancellation
Reserve now, pay when you stay
The price is CA $132 per night
CA $132
CA $151 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jorkerst Memorial Park and Sunset Park are located nearby.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Sunrise Lake Beach
Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?
Big Lake
Commune with nature and explore the great outdoors at Big Lake during your travels in De Soto.
Valle Lake Beach
Explore the great outdoors at Valle Lake Beach, a lovely green space in De Soto.
De Soto Vacations
Experiencing the real essence of De Soto starts with researching a few basic facts. Are you ready to find out just where this unique destination is and what attractions you should explore?
You can find it 12 miles (19 kilometers) from Bonne Terre and 12 miles (19 kilometers) away from Festus.
Love meeting the locals when you're on vacation? This corner of Missouri has a population of around 6,000 people.
Places to visit in De Soto
Want to alleviate the stress of your busy, urban life? Drink in the fresh air as you take off on an adventure through St. Francois State Park. Want some more ideas? Are you looking to relieve the stress of your busy, urban life? Savor the fresh air as you embark on an adventure through Washington State Park.Where do you fly into for De Soto?
Bags packed and passport at the ready? Excellent — hop on the plane to Spirit of St. Louis Airport (SUS). Once you hit the runway, you'll be just 40 miles (64 kilometers) from the main streets of De Soto.Frequently asked questions
Photos of local treasures
Browse De Soto vacation photos for more inspiration

