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21C Museum Hotel St Louis

4.5 star property
4.5-star luxury hotel near Enterprise Center

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Photo gallery for 21C Museum Hotel St Louis

Exterior
Indoor pool
Room, 1 King Bed, Corner
1 bedroom, in-room safe, desk, laptop workspace
Lobby

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • City Museum
    ‪6 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

Heart of St. Louis.Within a 10-minute walk of this Downtown West hotel, you'll find Enterprise Center and City Museum. Also, St. Louis Union Station is within half a mile (1 km) and Busch Stadium is within 2 miles (3 km).

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

4.5-star luxury hotel near Enterprise Center
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Meeting rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

Languages

English

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Property amenities

Family friendly

  • Indoor pool
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Entertainment

  • Flat-screen TV with premium digital channels

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in each accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 848 out of 1175 reviews
Rating 8 - Good. 180 out of 1175 reviews
Rating 6 - Okay. 66 out of 1175 reviews
Rating 4 - Poor. 35 out of 1175 reviews
Rating 2 - Terrible. 46 out of 1175 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Claudia

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel
Stayed 4 nights in Apr 2025

10/10 Excellent

Holly

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Mar 2025

10/10 Excellent

Bryan

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Great boutique hotel in downtown St. Louis, the hotel was busy when we checked in and the front desk staff was a bit harried, but they gave us the essential information we needed. The art gallery on the second floor was a great addition to our stay, as was the on sight restaurant, The Idol Wolf, amazing food, and service. The hotel itself has a very cool, and eclectic vibe, but is beginning to look a little “run down”. But overall a good experience, we will definitely stay here again if we are ever in the area.
Stayed 1 night in Mar 2025

10/10 Excellent

Lisa

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

chastity

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really clean and updated. The museum on the 2nd floor was nice to browse. Valet guys were funny and friendly. The gal at check in was not as friendly. Would stay here again for convenience to concerts, sporting events, etc.
Stayed 1 night in Mar 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

March 21c couples stay

The hotel, bar, restaurants and art were amazing. Would definitely stay here again. Some improvements; need a hair dryer in room without asking, need hooks in bathroom and need higher quality toilet paper.
Stayed 2 nights in Mar 2025

10/10 Excellent

Brandi

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Mar 2025

10/10 Excellent

Latisha

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice and comfortable hotel.
Stayed 2 nights in Jan 2025

10/10 Excellent

Amy

Stayed 4 nights in Feb 2025

10/10 Excellent

Jonathan

Stayed 5 nights in Feb 2025

6/10 Okay

Erin

Travelled with family
Disliked: Cleanliness
It was disappointing to walk into hotel and see dirty carpeted stairs, glasses from the night before left in the pool and health club areas and a bathroom barn door that didn't close all the way in our room. No towels were available for pool use, we were told by the rude attendant to use our room towels and it was quite a process to get extra clean towels to use after showers. This hotel has a lot of potential but was underwhelming. I would not stay here again.
Stayed 1 night in Mar 2025

8/10 Good

Andrew

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Cool, hip downtown spot!

First time staying here and aside from a few issues, it was a worthwhile stay. Hotel is an old YMCA that has been modernized and upgraded in a major way! Food options are worthy and showcased art is a nice bonus. Pool is also great! Except for a few “misses”this place would be Excellent.
Stayed 4 nights in Feb 2025

6/10 Okay

Jerry, Grimes

Stayed 1 night in Mar 2025

10/10 Excellent

Alexander

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I like
Stayed 2 nights in Feb 2025

10/10 Excellent

Griffin

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

8/10 Good

Deana

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good for a fun getaway weekend

The hotel is charming, built in the old YMCA building with a restored fitness pool, hot tub and sauna. Be aware that there is no free breakfast, hotels.com will list it was an option for an extra $3 but there is no free buffet style breakfast but there is an overpriced trendy breakfast cafe in the hotel, the coffee was great but the food took an hour to make and was not worth the price in my opinion. The tv in the room also does not have streaming services, you have to connect to their wifi and stream from your phone which is absolutely ridiculous in my opinion. Just provide simple tv options that play netflix/spotify on the tv.
Stayed 1 night in Feb 2025

8/10 Good

Emily

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel is beautiful, bar and restaurant are lovely, the hot tub, pool, and fitness area were great. The housekeeping was not thorough (forgot to leave coffee cups day 2, and didn't have conditioner). I had to go down to the desk to get these as they didn't have staff available to bring them up. Otherwise, great.
Stayed 2 nights in Mar 2025

10/10 Excellent

Lauren

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great for hockey games!
Stayed 1 night in Jan 2025

10/10 Excellent

Chris

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Mar 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful hotel, friendly staff. Great pool, lobby and coffee shop
Stayed 1 night in Mar 2025

10/10 Excellent

SARAH

Travelled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to a lot of things. Great location!
Stayed 1 night in Mar 2025

10/10 Excellent

Deion

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Feb 2025

10/10 Excellent

Charvez

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice room that uses its space very well. Love that there is a museum in the hotel and the restaurants were delicious as well!
Stayed 2 nights in Feb 2025

10/10 Excellent

Brenda

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Rooms were clean, modern and comfortable. Great experience. Staff were friendly and helpful. Would definitely stay at this hotel again and have recommended it to others.
Stayed 1 night in Feb 2025

10/10 Excellent

Randi, Las Vegas

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 4 nights in Feb 2025