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21C Museum Hotel St Louis

4.5 star property
4.5-star luxury hotel near St. Louis Union Station

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Photo gallery for 21C Museum Hotel St Louis

Interior
Dining
Loft, 2 Queen Beds
Exterior
Billiards

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, City Museum
    ‪6 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(76 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(23 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Loft, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Loft, 2 Queen Beds

  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About the area

St. Louis

Heart of St. Louis.Within a 10-minute walk of this Downtown West hotel, you'll find City Museum and Enterprise Center. Also, St. Louis Union Station is within half a mile (1 km) and Gateway Arch is within 2 miles (3 km).

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • America's Center Convention Complex - 12 min walk - 1.1 km
  • Busch Stadium - 14 min walk - 1.2 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Medina Grill - ‬5 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪White Knight Diner - ‬4 min walk
  • ‪Idol Wolf - ‬1 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk

About this property

21C Museum Hotel St Louis

4.5-star luxury hotel near St. Louis Union Station
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Meeting rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

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Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
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  • Free WiFi
  • Restaurant
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4.4 out of 5, Excellent, 1,110 reviews
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Property amenities

Family friendly

  • Indoor pool
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Entertainment

  • Flat-screen TV with premium digital channels

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in each accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Reviews

21C Museum Hotel St Louis Reviews

9.0

Wonderful

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness
Rating 10 - Excellent. 1059 out of 1468 reviews
Rating 8 - Good. 215 out of 1468 reviews
Rating 6 - Okay. 96 out of 1468 reviews
Rating 4 - Poor. 44 out of 1468 reviews
Rating 2 - Terrible. 54 out of 1468 reviews

Reviews

10/10 Excellent

Sarah

Stayed 2 nights in Aug 2025

6/10 Okay

Patricia

Liked: Staff & service, property conditions & facilities, room comfort

Just ok

Well to start this hotel has no ice machines, you have to go to the front desk for a bucket of ice. Valet parking, the gentleman that checked us in on 8-14 was as friendly as could be, not so much friendliness getting car on 8/16, different employee. Front counter checking on on 8/14 not very friendly early shift, lady that worked night shift was great. Water station didn't work on 10th floor. Cleaning lady was in my room at 9,10 and 11 on my 1st morning, I was staying for 2 nights. Was trying to sleep but that went out the window. No Do Not Disturb signs.. and check out isn't till 11, so why knocking on my door and just come on on my room at 9 & 10.... room needs good cleaning cobwebs hanging from lights and dust on lamps and headboard of bed, throw pillows had feathers coming out of them. No microwave in rooms and fridge wasn't very cold. Last curtain broke.Not sure I would stay here again
Stayed 1 night in Aug 2025

6/10 Okay

Catherine

Travelled with family and small children
Liked: Amenities
The ambience of the room was good. I didn’t like that they don’t have a microwave inside the room.
Stayed 1 night in Aug 2025

10/10 Excellent

Michael

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Just stayed one night for a quick business trip but was impressed. Staff was excellent and room was really nice. Looks like they have a nice bar and restaurant in the lobby but didn't have a chance to check it out. I did hit the coffeeshop in the morning and it was really nice. I'll certainly be back next time I need to come to town.
Stayed 1 night in Aug 2025

10/10 Excellent

Joe

Stayed 1 night in Aug 2025

10/10 Excellent

Angela

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Amazing hotel!
Stayed 1 night in Aug 2025

8/10 Good

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stay was fine and the room was comfortable. We did have an issue at checkout with someone trying to charge drinks to our room. The parking situation is also less than ideal. 50 dollar valet parking and it was just a lot on the street that didnt seem very safe for your vehicle. There was only street parking or another unfenced lot behind the hotel that was paid parking for 30 dollars.
Stayed 1 night in Aug 2025

10/10 Excellent

Tuan

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Valet too expensive ($50/day)
Stayed 3 nights in Aug 2025

6/10 Okay

Verified traveller

Liked: Staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Aug 2025

10/10 Excellent

Amanda

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel and great food options. Gym and pool were great also.
Stayed 1 night in Aug 2025

10/10 Excellent

Keri

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Patricia, Saint Charles

Liked: Cleanliness, staff & service, property conditions & facilities
Fun place to stay. Museum on the 2nd floor was so much fun.
Stayed 1 night in Aug 2025

10/10 Excellent

Jannie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Jennifer L

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
We enjoyed our stay! Close to Busch Stadium which was our destination. Staff was friendly and extremely helpful. Valet parking was worth it.
Stayed 2 nights in Aug 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Nice stay at 21c St. Louis

The valet and front desk staff were great! Everyone was friendly and helpful, really created a welcoming environment. The overnight parking is a little pricey, but they took good care of our car and offered a speedy retrieval when needed. Parking in the area is limited, and while there is some street parking, wasn’t sure it was secure enough for an overnight. The hotel amenities were wonderful. The indoor pool and hot tub were great, along with a really nice gym. All facilities were really clean. Be sure to check out the art galleries on the second floor. The gallery space was some of the best we’ve seen at a 21c Hotel. Free bottled water with easy refill stations was a plus. Our one critique was that our room carpet and bathroom floor could’ve used a better cleaning, and the rooms are showing some wear and tear. Not horrible, but we stayed here about two years ago for the first time, and the room was extremely clean and well cared for. Hopefully, they’ll pay better attention to this because it’s a nice hotel in a cool building and it would be a shame to let it fall into disrepair.
Stayed 1 night in Aug 2025

10/10 Excellent

Cicely

Liked: Property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025

10/10 Excellent

Andrea

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Bethany

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Laila

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

6/10 Okay

Veronica

Liked: Staff & service, property conditions & facilities
Nice hotel but the bathroom was dirty and the area was a little shady.
Stayed 1 night in Aug 2025

10/10 Excellent

Leslie

So different and classy
Stayed 1 night in Aug 2025

10/10 Excellent

Edward

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Aug 2025

10/10 Excellent

Matthew

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always enjoy staying at this hotel. Staff is always willing to lend a hand. Love the pool, art, and other amenities.
Stayed 2 nights in Jun 2025