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21C Museum Hotel St Louis

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Photo gallery for 21C Museum Hotel St Louis

A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A gym with treadmills, weight machines, and free weights.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A hotel room with two beds, a sofa, a television, and a painting on the wall.

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, City Museum
    ‪5 min walk‬
  • Place, St. Louis Union Station
    ‪8 min walk‬
  • Place, Enterprise Center
    ‪8 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪20 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

A hotel room with a bed, an orange armchair, a small round table, a desk with a lamp, and a decorative vase.

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(127 reviews)
  • 29 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Luxury Double Room, 2 Queen Beds

A hotel room with a wooden floor, a desk with drawers, a chair, a bed with a headboard, and curtains.

Luxury Double Room, 2 Queen Beds

9.4 out of 10
Exceptional
(40 reviews)
  • 39 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Room (Bunk Bed)

A modern hotel room with a bunk bed, a round table with a plant, an orange armchair, and a colorful abstract painting on the wall.

Room (Bunk Bed)

8.6 out of 10
Excellent
(9 reviews)
  • 22 sq m
  • Sleeps 2
  • 1 Twin Bunk Bed
  • Free WiFi

Loft, 2 Queen Beds

9.0 out of 10
Wonderful
(2 reviews)
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

Deluxe Room, Accessible (Accessible)

10.0 out of 10
Exceptional
(1 review)
  • 25 sq m
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed (21C)

A hotel room with a bed, bedside tables, a lamp, a mirror, and a patterned wall.

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

Suite, 1 King Bed (Library)

  • City view
  • 68 sq m
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

Luxury Suite, 1 King Bed

9.4 out of 10
Exceptional
(3 reviews)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Room, 1 Double Bed, Accessible

A hotel room with two beds, a sofa, a television, and a painting on the wall.

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed
  • Free WiFi

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed
  • Free WiFi

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About the area

St. Louis

Heart of St. Louis.Within a 10-minute walk of this Downtown West hotel, you'll find St. Louis Union Station and City Museum. Also, Enterprise Center is within half a mile (1 km) and Gateway Arch is within 2 miles (3 km).

What's nearby

  • Washington Avenue Historic District - 2 min walk - 0.2 km
  • City Museum - 5 min walk - 0.4 km
  • St. Louis Union Station - 8 min walk - 0.7 km
  • Enterprise Center - 8 min walk - 0.7 km
  • St. Louis Aquarium at Union Station - 11 min walk - 1.0 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 24 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Imo's Pizza Headquarters & Retail Store - ‬7 min walk
  • ‪Medina Grill - ‬5 min walk
  • ‪Good Press - ‬1 min walk

About this property

21C Museum Hotel St Louis

4.5-star luxury hotel near St. Louis Union Station
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Meeting rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Elevator
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guests can pamper themselves by indulging in the onsite spa services. Services include massages.

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  • Pet friendly
  • Free WiFi
  • Restaurant
  • Air conditioning
4.3 out of 5, Excellent, 4,201 reviews
The price is CA $186
CA $219 total
includes taxes & fees
Sep 4 - Sep 5
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Property amenities

Family friendly

  • Indoor pool
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 55 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Entertainment

  • Flat-screen TV with premium digital channels

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 55 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, and American Express. Cash is not accepted. For guests' safety, the property includes a fire extinguisher, a smoke detector, and outdoor lighting in each accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

How close is 21C Museum Hotel St Louis to the airport?

21C Museum Hotel St Louis is 18.4 mi (24-min drive) away from the St. Louis Lambert Intl. Airport (STL) airport, the closest popular airport to the property.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of Sept 3, 2026, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on Sept 27, 2026 start from CA $199, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does 21C Museum Hotel St Louis have an airport shuttle?

Airport shuttle services are not available at 21C Museum Hotel St Louis .

Does 21C Museum Hotel St Louis offer free breakfast?

Free breakfast isn’t provided at 21C Museum Hotel St Louis , but cooked-to-order breakfast is offered for a fee of between USD 10 and 25 per person. It's available every day from 6:30 AM to 1:00 PM.

Is there a casino at 21C Museum Hotel St Louis ?

No, there is no casino at this hotel, but Horseshoe St. Louis Casino (3-min drive) and Casino Queen (5-min drive) are nearby.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM.

Is there free parking at 21C Museum Hotel St Louis ?

Free parking is not available at this hotel. Valet parking is available for USD 55 per day.

Does 21C Museum Hotel St Louis have a pool?

21C Museum Hotel St Louis features an indoor pool.

Does 21C Museum Hotel St Louis have a restaurant?

Yes, there is a restaurant on site.

Does 21C Museum Hotel St Louis have a spa?

This hotel doesn't have a spa, but it does offer massages.

How close is 21C Museum Hotel St Louis to downtown St. Louis?

21C Museum Hotel St Louis is 0.4 mi away from St. Louis.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1472 out of 2087 reviews
Rating 8 - Good. 320 out of 2087 reviews
Rating 6 - Okay. 149 out of 2087 reviews
Rating 4 - Poor. 68 out of 2087 reviews
Rating 2 - Terrible. 78 out of 2087 reviews

9.2/10

Cleanliness

9.0/10

Staff & service

9.0/10

Amenities

9.2/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Alexander

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Myerisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The stay was amazing!! Will be staying again!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Molly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place and I would stay here again next time in St Louis
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Matthew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice classic clean hotel
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Juan

Liked: Cleanliness, staff & service, property conditions & facilities
Great place to stay.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
All the restaurants and bar were excellent.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Carl

Liked: Cleanliness
Great stay
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Kenneth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location, clean rooms, wonderful pool and hot tub
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Meeta

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay. Pool/spa area is great and well maintained. Restaurant /bar were great and bartenders and front desk staff was great. Parking is way too expensive but valet drivers/staff were very friendly and efficient.
Stayed 3 nights in May 2026
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location, staff, and bar/restaurant. The art gallery is an incredible bonus, along with the workout facilities!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Jenlyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I loved the art museum, the bar and cafe. The staff were so friendly and helpful
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Elizabeth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The rooms were clean and common areas well maintained. Breakfast was the best and the staff were all helpful and very kind to all guests. It was the best stay I've had in a hotel.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Porsha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I loved this hotel! It truly felt like a nice getaway and was absolutely beautiful! The Staff was very nice and professional. We ate breakfast where the coffee shop was and the breakfast burrito was so good! We will be back!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Erika

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel. It has multiple restaurants and an art gallery along with an Olympic sized pool and Jacuzzi. I travelled with teenage boys and we thoroughly enjoyed our stay. Very unique property.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean and serviced daily. Hotel was lovely and well appointed.
Stayed 3 nights in Apr 2026
Verified review

10/10 Excellent

Rick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Our one-night stay completely exceeded our expectations. Worth every penny.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Rebecca

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful hotel
Stayed 3 nights in Mar 2026
Verified review

10/10 Excellent

sean

Location was wonderful, chris the bartender is fantastic
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Julie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wow! Would stay here again in a heartbeat! Clean, posh, the pool area is exquisite and the honey latte in the cafe is the best I’ve ever had. Check out the wallpapered stairwell! Fun photo ops!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff at front desk attentive and helpful Both places to eat onsite offer gluten free which was nice.
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is my favorite hotel in the united states of America
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Alina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fun hotel
Stayed 3 nights in Apr 2026
Verified review

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Absolutely beautiful, amazing breakfast, comfy bed!
Stayed 1 night in Feb 2026