Hampton Inn & Suites St. Louis/South I-55
St. Louis guestrooms with free WiFi
Choose dates to view prices
Photo gallery for Hampton Inn & Suites St. Louis/South I-55





Reviews
9.6 out of 10
Exceptional
Popular amenities
Explore the area

4200 Midamerica Lane, St. Louis, MO, 63129
- Place, Busch Stadium16 min drive
- Place, Gateway Arch17 min drive
- Place, St. Louis Union Station18 min drive
- Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)29 min drive
Room options
View all photos for Room

Room
9.8 out of 10
Exceptional
(41 reviews)
View all photos for Room

Room
9.6 out of 10
Exceptional
(15 reviews)
View all photos for Room

Room
9.6 out of 10
Exceptional
(4 reviews)
View all photos for Room

Room
10.0 out of 10
Exceptional
(2 reviews)
View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(27 reviews)
View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(21 reviews)
View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking
8.0 out of 10
Very good
(6 reviews)
King Room-Non-Smoking
Guest Room With 1 King Bed And Mobility/Hearing Accessible With Tub-Nonsmoking
King Studio Suite With Whirlpool-Non-Smoking
2 Queen Beds Room, Non-Smoking
Mobility Hearing Accessible King Studio with Roll in Shower
2 Queens Mobility/Hearing Access Tub Nosmok
King Studio Suite-Non-Smoking
You may also like
Ad

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Fenton
- Pool
- Breakfast included
- Pet friendly
- Free WiFi
4.4 out of 5, Excellent, 1,011 reviews
The price is CA $144
CA $166 total
includes taxes & fees
Jun 14 - Jun 15
About the area
About this property
Hampton Inn & Suites St. Louis/South I-55
Similar properties

Best Western St. Louis Inn
St. Louis
Best Western St. Louis Inn
- Pool
- Breakfast included
- Pet friendly
- Kids pool
4.1 out of 5, Very good, 1,022 reviews
The price is CA $111
CA $128 total
includes taxes & fees
May 25 - May 26
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Hampton Inn & Suites St. Louis/South I-55 Reviews
Reviews
9.6
Exceptional
9.6/10
Cleanliness
9.8/10
Staff & service
9.4/10
Amenities
9.6/10
Property conditions & facilities
Reviews
Feb 9, 2026
Stayed 2 nights in Feb 2026
10/10 Excellent
Josi
Jan 31, 2026
Liked: Cleanliness, staff & service, amenities
Josi
Stayed 1 night in Jan 2026
2/10 Terrible
Lonnie
Jan 19, 2026
Lonnie
Stayed 1 night in Jan 2026
10/10 Excellent
Yvonne
Jan 14, 2026
Yvonne
Stayed 1 night in Jan 2026
10/10 Excellent
Miliska
Travelled with family, Travelled with group
Jan 5, 2026
Liked: Cleanliness, staff & service, amenities
Miliska
Stayed 1 night in Jan 2026
10/10 Excellent
Manivannan
Travelled with family, Travelled with group
Dec 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Manivannan
Stayed 1 night in Dec 2025
2/10 Terrible
Jason
Dec 15, 2025
Liked: Staff & service
Disliked: Cleanliness, amenities
Jason
Stayed 2 nights in Dec 2025
10/10 Excellent
Joan
Dec 11, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Joan
Stayed 4 nights in Dec 2025
8/10 Good
Gretchen
Dec 10, 2025
Gretchen
Stayed 3 nights in Dec 2025
10/10 Excellent
SHELLY
Travelled with family
Dec 8, 2025
Liked: Cleanliness, staff & service, amenities
SHELLY
Stayed 1 night in Dec 2025
8/10 Good
Jeffrey
Travelled with family
Dec 6, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Jeffrey
Stayed 1 night in Dec 2025
2/10 Terrible
Tabitha
Dec 3, 2025
Liked: Cleanliness
Disliked: Staff & service
Tabitha
Stayed 1 night in Dec 2025
8/10 Good
Jessica
Nov 29, 2025
Liked: Cleanliness, property conditions & facilities, room comfort
Jessica
Stayed 1 night in Nov 2025
10/10 Excellent
Randall
Nov 24, 2025
Randall
Stayed 1 night in Nov 2025
8/10 Good
Cynthia
Travelled with family
Nov 22, 2025
Liked: Cleanliness, staff & service, amenities
Cynthia
Stayed 1 night in Nov 2025
10/10 Excellent
Samiha
Nov 20, 2025
Samiha
Stayed 3 nights in Nov 2025
10/10 Excellent
Amy
Travelled with family and small children, Business traveller
Nov 17, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amy
Stayed 1 night in Nov 2025
10/10 Excellent
Sherry
Oct 30, 2025
Sherry
Stayed 1 night in Oct 2025
10/10 Excellent
Michael
Travelled with partner
Oct 23, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Michael
Stayed 1 night in Oct 2025
10/10 Excellent
Lísbeth
Travelled with family and small children
Oct 20, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lísbeth
Stayed 2 nights in Oct 2025
10/10 Excellent
Eric
Travelled with family
Oct 19, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Eric
Stayed 1 night in Oct 2025
8/10 Good
Melinda
Business traveller
Oct 14, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Melinda
Stayed 1 night in Oct 2025
10/10 Excellent
Vicenta Fe
Travelled with family, Travelled with group
Oct 12, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Vicenta Fe
Stayed 1 night in Oct 2025
10/10 Excellent
Renee
Oct 11, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Renee
Stayed 1 night in Oct 2025
10/10 Excellent
Melissa
Oct 9, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Melissa
Stayed 3 nights in Oct 2025
Travelocity's Latest Trends
Hotels
- Cheap Hotels in Paisley
- Rochester Waterpark Hotels and Resorts
- RV Parks Tofino
- Country Inn & Suites by Radisson, Niagara Falls, ON
- Hampton Inn by Hilton Ottawa
- Cheap Hotels in North Bay
- Cheap Hotels in Newport
- Cornwall Pet Friendly Hotels
- Houseboat Rentals Kelowna
- RV Parks Canada
- Prince Rupert Hotels with Hot Tubs
- B&B Fogo Island
- B&B Bancroft
- Thorold Hotels with Hot Tubs
- The Holman Grand Hotel
- Secrets Huatulco Resort & Spa - Adults Only - All Inclusive
Flights
- Cheap Flights to Kamloops
- Edmonton to Lethbridge (YEG - YQL)
- Air Canada Winnipeg (YWG) to New Brunswick (ZBF) flights
- Icelandair Edmonton (YEG) to Suðurnesjabær (KEF) flights
- Flights from Calgary to Saskatoon
- Air Canada Chicago (ORD) to London (YXU) flights
- Air Canada Edmonton (YEG) to Sidney (YYJ) flights
- WestJet Simpson Bay (SXM) to Toronto (YYZ) flights
- WestJet Goffs (YHZ) to Toronto (YYZ) flights
Activities

















