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Featured Buffalo 4 Star hotels

The Delavan Hotel & Spa

The Delavan Hotel & Spa

4 out of 5
6461 Transit Road Bowmansville NY
Fully refundableReserve now, pay when you stay
The price is CA $160 per night from May 27 to May 28
CA $160
CA $182 total
May 27 - May 28
includes taxes & fees
Book a stay at this business-friendly hotel in Bowmansville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,005 reviews)
"Enjoyed our stay. Beautiful hotel."

Reviewed on May 22, 2026

Opens in a new windowThe Delavan Hotel & Spa
The Mansion On Delaware Ave

The Mansion On Delaware Ave

4 out of 5
414 Delaware Ave Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $323 per night from May 31 to Jun 1
CA $323
CA $371 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the bar in our ...
9.4/10 Exceptional! (1,004 reviews)
"A gorgeous place to stay with beautiful vaulted ceilings. Our room had a gas fireplace, and the bed was comfy. The bathroom was very nice with double sinks. The staff was just incredible! We highly recommend the breakfast, so yummy! Caveat: The internet access is very limited."

Reviewed on May 23, 2026

Opens in a new windowThe Mansion On Delaware Ave
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

4 out of 5
5195 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $218 per night from May 30 to May 31
CA $218
CA $248 total
May 30 - May 31
includes taxes & fees
Book a stay at this spa hotel in Buffalo. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (1,003 reviews)
"Nice to have the restaurant and spa on property. Rooms were clean and spacious and location was convenient. Free parking is a great perk! There’s plenty of restaurants and coffee shops within walking distance"

Reviewed on May 22, 2026

Opens in a new windowThe Mosey Buffalo Williamsville, Tapestry Collection by Hilton
DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst

4 out of 5
10 Flint Rd Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from May 28 to May 29
CA $158
CA $179 total
May 28 - May 29
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
7.8/10 Good! (1,004 reviews)
"I don’t think I will go there again.."

Reviewed on May 23, 2026

Opens in a new windowDoubleTree by Hilton Hotel Buffalo - Amherst
Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

4 out of 5
5000 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
The price is CA $344 per night from May 25 to May 26
CA $344
CA $391 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (718 reviews)
"Great staff and amenities as well as good restaurant next door"

Reviewed on May 21, 2026

Opens in a new windowReikart House, Buffalo, a Tribute Portfolio Hotel
The Westin Buffalo

The Westin Buffalo

4 out of 5
250 Delaware Ave Buffalo NY
The price is CA $372 per night from May 25 to May 26
CA $372
CA $434 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (417 reviews)
"Amazing hotel. Everything was super clean and nice."

Reviewed on Apr 12, 2026

Opens in a new windowThe Westin Buffalo
Buffalo Harmony House

Buffalo Harmony House

4.5 out of 5
70 Wadsworth Street Buffalo NY
The price is CA $342 per night from May 26 to May 27
CA $342
CA $399 total
May 26 - May 27
includes taxes & fees
Book a stay at this luxury B&B in Buffalo. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast in our reviews. Popular attractions ...
10/10 Exceptional! (50 reviews)
"Great stay - nice breakfast, good area and good people. Would stay again."

Reviewed on May 19, 2026

Opens in a new windowBuffalo Harmony House
Lofts on Pearl Trademark Collection by Wyndham

Lofts on Pearl Trademark Collection by Wyndham

4 out of 5
92 Pearl Street Buffalo NY
Stay at this apartment in Buffalo. Enjoy free WiFi, 2 restaurants, and a 24-hour front desk. Popular attractions KeyBank Center and Walden Galleria Mall are ...
9.2/10 Wonderful! (520 reviews)
Great location
"Very easy and fast check in. Property manager managed to find ways to connect with me after unable to contact Expedia that our original property is closed on Sunday and we have to move to another property. The info provided was accurate. The location is really good. Close to city and easy access ..."

Reviewed on Oct 14, 2020

Opens in a new windowLofts on Pearl Trademark Collection by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Buffalo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Buffalo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Buffalo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Buffalo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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