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Featured Syros 4 Star hotels

Hotel Alkyon

Hotel Alkyon

4 out of 5
Dexamenes Mykonos Mykonos Island
The price is CA $173 per night from May 1 to May 2
CA $173
CA $213 total
May 1 - May 2
includes taxes & fees
Stay at this hotel in Mykonos. Enjoy free WiFi, free parking, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (732 reviews)
The staff was so friendly here! Hotel was very clean, rooms had everything you needed and were very clean and spacious. The views from the hotel are 10/10. Hotel is about a 10 minute walk from Little Venice.

Reviewed on Oct 11, 2025

Opens in a new windowHotel Alkyon
Harmony Boutique Hotel

Harmony Boutique Hotel

4 out of 5
Mykonos Town Mykonos Mykonos Island
The price is CA $141 per night from Apr 14 to Apr 15
CA $141
CA $177 total
Apr 14 - Apr 15
includes taxes & fees
Book a stay at this spa hotel in Mykonos. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (479 reviews)
Beautiful hotel and rooms! Perfect location and lovely staff!

Reviewed on Apr 12, 2026

Opens in a new windowHarmony Boutique Hotel
Hermes Mykonos Hotel

Hermes Mykonos Hotel

4 out of 5
Mykonos Town Mykonos Mykonos Island
The price is CA $194 per night from May 1 to May 2
CA $194
CA $238 total
May 1 - May 2
includes taxes & fees
Stay at this hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (918 reviews)
Good location, beautiful views, comfortable rooms, helpful staff.

Reviewed on Jan 30, 2026

Opens in a new windowHermes Mykonos Hotel
Kosmoplaz Beach Hotel

Kosmoplaz Beach Hotel

4 out of 5
Platis Gialos Beach Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Apr 13 to Apr 14
CA $121
CA $154 total
Apr 13 - Apr 14
includes taxes & fees
Book a stay at this beach hotel in Mykonos. Enjoy free breakfast, free WiFi, and private pools. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (278 reviews)
My stay at this hotel was extremely disappointing. There was ongoing construction throughout the property, which was never clearly communicated beforehand. To make matters worse, the elevator was not working, which was very inconvenient—especially when traveling with a disabled person. The entire ...

Reviewed on Apr 7, 2026

Opens in a new windowKosmoplaz Beach Hotel
Hotel Petinos

Hotel Petinos

4 out of 5
Platy Gialos Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $179 per night from Apr 14 to Apr 15
CA $179
CA $220 total
Apr 14 - Apr 15
includes taxes & fees
Book a stay at this beach hotel in Mykonos. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (720 reviews)
Everything and everyone was amazing! Yota, Maria and all the other staff were wonderful, the hotel smells really good and very clean. I would recommend everyone to go to this hotel 100%

Reviewed on Apr 10, 2026

Opens in a new windowHotel Petinos
Poseidon Hotel & Suites

Poseidon Hotel & Suites

4 out of 5
Mykonos Town Mykonos Mykonos Island
The price is CA $176 per night from Apr 18 to Apr 19
CA $176
CA $217 total
Apr 18 - Apr 19
includes taxes & fees
Book a stay at this business-friendly hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (1,003 reviews)
』 I had a wonderful stay at this hotel! Everything exceeded my expectations - the rooms were spotless and very comfortable, the staff was incredibly friendly and attentive, and the breakfast was fresh and delicious every morning. The location is perfect, close to town and great food spots, which ...

Reviewed on Apr 10, 2026

Opens in a new windowPoseidon Hotel & Suites
Vencia Boutique Hotel

Vencia Boutique Hotel

4 out of 5
Mykonos Mykonos
Fully refundableReserve now, pay when you stay
The price is CA $162 per night from Apr 26 to Apr 27
CA $162
CA $201 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this spa hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in ...
9.8/10 Exceptional! (404 reviews)
Amazing views, great location, room was large and outside area was well maintained.

Reviewed on Oct 19, 2025

Opens in a new windowVencia Boutique Hotel
Casa Grande

Casa Grande

4 out of 5
Platis Yialos Mykonos
The price is CA $104 per night from May 8 to May 9
CA $104
CA $134 total
May 8 - May 9
includes taxes & fees
Stay at this hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mykonos Old Port and Mykonos New Port are located ...
Opens in a new windowCasa Grande
Andronikos Hotel - Adults Only

Andronikos Hotel - Adults Only

4 out of 5
Drafaki Mykonos Mykonos Island
The price is CA $259 per night from May 12 to May 13
CA $259
CA $311 total
May 12 - May 13
includes taxes & fees
Book a stay at this spa hotel in Mykonos. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (414 reviews)
Great stay perfect location

Reviewed on Mar 20, 2026

Opens in a new windowAndronikos Hotel - Adults Only
Petinos Beach Hotel

Petinos Beach Hotel

4 out of 5
Plati Gialos Mykonos Mykonos Island
Fully refundableReserve now, pay when you stay
The price is CA $249 per night from Apr 13 to Apr 14
CA $249
CA $299 total
Apr 13 - Apr 14
includes taxes & fees
Book a stay at this beach hotel in Mykonos. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Mykonos Old Port and Mykonos New Port are ...
9.2/10 Wonderful! (320 reviews)
It was a great place, I liked it. The only thing was the shower which is very uncomfortable to get in and out.

Reviewed on Oct 31, 2025

Opens in a new windowPetinos Beach Hotel
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4 Star Hotels Syros

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Syros 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Syros will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Syros, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Syros hotel reviews by fellow wanderers