Find and compare 5 Star hotels in Thessaloniki

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Featured Thessaloniki 5 Star hotels

Electra Palace Thessaloniki

Electra Palace Thessaloniki

5 out of 5
9, Aristotelous Square Thessaloniki Central Macedonia
Fully refundable
The price is CA $282 per night from Jun 3 to Jun 4
CA $282
CA $321 total
Jun 3 - Jun 4
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free breakfast, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"It’s centrally located, nice sea view, best rooftop restaurant."

Reviewed on May 21, 2026

Opens in a new windowElectra Palace Thessaloniki
ON Residence

ON Residence

5 out of 5
5 Leof. Nikis Thessaloniki
The price is CA $283 per night from Jun 22 to Jun 23
CA $283
CA $347 total
Jun 22 - Jun 23
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.8/10 Exceptional! (192 reviews)
"Great modern hotel in excellent location and staff are wonderful! Loved the rooftop - only minor drawback is that the gym is very small."

Reviewed on May 3, 2026

Opens in a new windowON Residence
Mediterranean Palace Hotel

Mediterranean Palace Hotel

5 out of 5
Salaminos 3 and Karatassou Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
The price is CA $270 per night from Jun 16 to Jun 17
CA $270
CA $331 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free WiFi, a full-service spa, and room service. Our guests praise the helpful staff and the property ...
9/10 Wonderful! (557 reviews)
"VERY NICE HOTEL"

Reviewed on May 20, 2026

Opens in a new windowMediterranean Palace Hotel
September Hotel Thessaloniki

September Hotel Thessaloniki

5 out of 5
16-18 Asklipiou, 99 Pylaia-Chortiatis Central Macedonia
The price is CA $171 per night from May 31 to Jun 1
CA $171
CA $218 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this luxury hotel in Pylaia-Chortiatis. Enjoy free WiFi, an outdoor pool, and a full-service spa. Popular attractions Go Kart Center and Mediterranean ...
9/10 Wonderful! (58 reviews)
"Just great"

Reviewed on Feb 1, 2026

Opens in a new windowSeptember Hotel Thessaloniki
The Met Hotel, a member of Design Hotels

The Met Hotel, a member of Design Hotels

5 out of 5
48, 26th October Street Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
The price is CA $209 per night from May 24 to May 25
CA $209
CA $262 total
May 24 - May 25
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Popular attractions Thessaloniki Port and One Salonica ...
9.2/10 Wonderful! (876 reviews)
"Great place to"

Reviewed on May 19, 2026

Opens in a new windowThe Met Hotel, a member of Design Hotels
Vanoro Hotel

Vanoro Hotel

5 out of 5
6 Dodekanisou Thessaloniki
Fully refundableReserve now, pay when you stay
The price is CA $160 per night from May 24 to May 25
CA $160
CA $182 total
May 24 - May 25
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (229 reviews)
"Convenient location, great Staff, very clean and amazing breakfast."

Reviewed on May 17, 2026

Opens in a new windowVanoro Hotel
Makedonia Palace

Makedonia Palace

5 out of 5
2, Megalou Alexandrou Avenue Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
The price is CA $323 per night from Jun 6 to Jun 7
CA $323
CA $392 total
Jun 6 - Jun 7
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (1,000 reviews)
"Excellent breakfast, clean, well constructed"

Reviewed on Apr 26, 2026

Opens in a new windowMakedonia Palace
ONOMA Hotel

ONOMA Hotel

5 out of 5
Monastiriou 24 Thessaloniki
Fully refundableReserve now, pay when you stay
The price is CA $213 per night from May 24 to May 25
CA $213
CA $266 total
May 24 - May 25
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (159 reviews)
"We stayed at the Onoma Hotel on a short family trip to Thessaloniki in May 2026. The hotel is located right outside of the center, a pleasant 15-20 min walk to the popular main streets (shops/restaurants etc). The lobby is well designed and has a good atmosphere. We stayed at a family room, which ..."

Reviewed on May 18, 2026

Opens in a new windowONOMA Hotel
The Excelsior Small Luxury Hotels of the World

The Excelsior Small Luxury Hotels of the World

5 out of 5
10 Komninon St. & 23 Mitropoleos Av. Thessaloniki Central Macedonia
The price is CA $235 per night from Jun 22 to Jun 23
CA $235
CA $292 total
Jun 22 - Jun 23
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (426 reviews)
"We had two rooms, the room to the street was larger than room with view to garden, Breakfast was good, but little narrow space if many people same time. Very central hotel to all points of interests."

Reviewed on Apr 12, 2026

Opens in a new windowThe Excelsior Small Luxury Hotels of the World
Daios Luxury Living

Daios Luxury Living

5 out of 5
Nikis Avenue 59 Thessaloniki Central Macedonia
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from May 24 to May 25
CA $276
CA $338 total
May 24 - May 25
includes taxes & fees
Book a stay at this luxury hotel in Thessaloniki. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowDaios Luxury Living
Don't see what you're looking for?
See all available properties in Thessaloniki
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Thessaloniki

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Thessaloniki to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Thessaloniki 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Thessaloniki before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Thessaloniki hotel reviews by fellow wanderers