Find and compare 5 Star hotels in Vacaville

Name: The Queen On Main
Price range: CA $750

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Featured Vacaville 5 Star hotels

Casa Mani Resort Napa Valley, Curio Collection by Hilton

1075 California Blvd Napa CA

Fully refundableReserve now, pay when you stay

CA $447

CA $515 total

Nov 22 - Nov 23

includes taxes & fees

Book a stay at this luxury resort in Napa. Enjoy 2 restaurants, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff ...

9.4/10 Exceptional! (134 reviews)

"Very nice hotel great luxury rooms current updated provisions"

Reviewed on Oct 18, 2026

The Meritage Resort and Spa

875 Bordeaux Way Napa CA

Fully refundableReserve now, pay when you stay

CA $348

CA $480 total

Nov 1 - Nov 2

includes taxes & fees

Book a stay at this luxury resort in Napa. Enjoy 2 outdoor pools, a full-service spa, and 3 restaurants. Popular attractions Napa Valley Wine Train and Trinitas ...

Stanly Ranch, Auberge Collection

200 Stanly Crossroad Napa CA

CA $876

CA $1,130 total

Nov 16 - Nov 17

includes taxes & fees

Book a stay at this luxury hotel in Napa. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Napa Valley Wine Train and Ceja Vineyards ...

9.6/10 Exceptional! (246 reviews)

"Honestly, the most beautiful property I’ve ever stayed at. From the service to the amenities everything was five star diamond star all the way."

Reviewed on Oct 6, 2026

The Estate Yountville

6481 Washington Street Yountville CA

CA $689

CA $907 total

Nov 15 - Nov 16

includes taxes & fees

Book a stay at this luxury hotel in Yountville. Enjoy free breakfast, free WiFi, and 3 outdoor pools. Our guests praise the breakfast and the helpful staff in ...

9.4/10 Exceptional! (1,001 reviews)

"Beautiful room"

Reviewed on Oct 23, 2026

Carneros Resort and Spa

4048 Sonoma Hwy Napa CA

CA $747

CA $973 total

Nov 2 - Nov 3

includes taxes & fees

Book a stay at this luxury hotel in Napa. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Napa Valley Wine Train and Domaine Carneros ...

9.2/10 Wonderful! (393 reviews)

"The staff at reception are wonderful - kind and helpful. We received the best recommendation for wine tasting and even helped to book for us a time slot. The room service was slow however and the cottages whilst charming are a little tired and could do with a refresh. Same goes for the towels and ..."

Reviewed on Oct 18, 2026

Bardessono Hotel and Spa

6526 Yount Street Yountville CA

CA $730

CA $957 total

Nov 24 - Nov 25

includes taxes & fees

Book a stay at this luxury resort in Yountville. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...

9.8/10 Exceptional! (755 reviews)

"Beautiful property in Napa Valley - like Living in an art museum- beautiful grounds ,water features ,sculpture and art. Very comfortable room- love the Nespresso ! VERY helpful attentive staff- shout out to the valets ! So awesome and friendly. Loved the complimentary shuttle /ride service. Thank ..."

Reviewed on Oct 17, 2026

Auberge Du Soleil

180 Rutherford Hill Rd St. Helena CA

CA $1,932

CA $2,226 total

Nov 18 - Nov 19

includes taxes & fees

Book a stay at this luxury hotel in St. Helena. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Rutherford Hill Winery and Quintessa ...

9.6/10 Exceptional! (121 reviews)

"Lovely stay all around"

Reviewed on Oct 7, 2026

The Queen On Main

11 E Main St Winters CA

CA $750

CA $855 total

Oct 25 - Oct 26

includes taxes & fees

Book a stay at this luxury vacation home in Winters. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Rotary Park and Turkovich Family ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Vacaville

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Vacaville to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vacaville 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Vacaville before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.