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Featured San Mateo 4 Star hotels

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $237 per night from Dec 14 to Dec 15
CA $237
CA $343 total
Dec 14 - Dec 15
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,961 reviews)
Our stay at the Hyatt Regency San Francisco was truly wonderful! The location is perfect — as a mother of two, it was such a relief to be able to step right outside and enjoy the beautiful piers with my family without needing a car (which is great since parking in San Francisco can be tricky). We ...

Reviewed on Nov 7, 2025

Opens in a new windowHyatt Regency San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Dec 12 to Dec 13
CA $125
CA $148 total
Dec 12 - Dec 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,973 reviews)
I think overall good experience among many hotels options. Convinient location and trust brand.

Reviewed on Nov 8, 2025

Opens in a new windowHilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Nov 30 to Dec 1
CA $153
CA $238 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
8.8/10 Excellent! (7,061 reviews)
Hotel and room was a it older, but well taken care of. Staff went above and beyond with their friendly welcome and assistance along the way. Continental breakfast felt like we arrived for a reservation, handled with care. Food was above average and was just right to start our day! Thank you, we will ...

Reviewed on Nov 9, 2025

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $195 per night from Nov 23 to Nov 24
CA $195
CA $287 total
Nov 23 - Nov 24
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
8.6/10 Excellent! (1,468 reviews)
Everything ok

Reviewed on Nov 3, 2025

Opens in a new windowHyatt Centric Fisherman's Wharf San Francisco
Oakland Marriott City Center

Oakland Marriott City Center

4 out of 5
1001 Broadway, Oakland, CA
Fully refundableReserve now, pay when you stay
The price is CA $156 per night from Nov 30 to Dec 1
CA $156
CA $181 total
Nov 30 - Dec 1
includes taxes & fees
Stay at this 4-star golf hotel in Oakland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,006 reviews)
good

Reviewed on Nov 11, 2025

Opens in a new windowOakland Marriott City Center
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $137 per night from Nov 26 to Nov 27
CA $137
CA $162 total
Nov 26 - Nov 27
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,718 reviews)
Room was clean, staff were very nice!

Reviewed on Nov 10, 2025

Opens in a new windowClub Quarters Hotel in San Francisco
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4 out of 5
50 3rd St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $203 per night from Nov 27 to Nov 28
CA $203
CA $295 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,301 reviews)
The staff and the hotel were both amazing

Reviewed on Nov 11, 2025

Opens in a new windowHyatt Regency San Francisco Downtown SOMA
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street, San Francisco, CA
Fully refundable
The price is CA $178 per night from Nov 27 to Nov 28
CA $178
CA $258 total
Nov 27 - Nov 28
includes taxes & fees
Stay at this 4-star luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,178 reviews)
Loved this classic, old, historic, well located icon. The amenities were minimal, example, no coffee in room, soaps and shampoo on the wall only. No bar soap. Very little luxury other than walls itself. We had dinner in the restaurant and unknowingly (cost) ordered 6 bottles of water for the table ...

Reviewed on Nov 7, 2025

Opens in a new windowInterContinental Mark Hopkins by IHG
Hyatt Regency Santa Clara

Hyatt Regency Santa Clara

4 out of 5
5101 Great America Pkwy, Santa Clara, CA
Fully refundableReserve now, pay when you stay
The price is CA $237 per night from Nov 21 to Nov 22
CA $237
CA $279 total
Nov 21 - Nov 22
includes taxes & fees
Book a stay at this eco-certified hotel in Santa Clara. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
All staff, including front desk, restaurant, were incredibly friendly and helpful. The room was spacious, clean and pillows were comfy. Thanks for a great stay!

Reviewed on Nov 3, 2025

Opens in a new windowHyatt Regency Santa Clara
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is CA $405 per night from Nov 25 to Nov 26
CA $405
CA $452 total
Nov 25 - Nov 26
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.6/10 Exceptional! (1,436 reviews)
Nice room, would have liked a blanket though

Reviewed on Nov 9, 2025

Opens in a new windowGrand Hyatt at SFO
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4 Star Hotels San Mateo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Mateo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Mateo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Mateo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Mateo hotel reviews by fellow wanderers