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Featured San Francisco 4 Star hotels

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $166 per night from Nov 8 to Nov 9
CA $166
CA $253 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $278 per night from Nov 7 to Nov 8
CA $278
CA $392 total
Nov 7 - Nov 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Opens in a new windowHyatt Regency San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from Nov 29 to Nov 30
CA $131
CA $154 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Opens in a new windowHilton San Francisco Financial District
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4 out of 5
345 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $246 per night from Nov 13 to Nov 14
CA $246
CA $355 total
Nov 13 - Nov 14
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,044 reviews)
"Loved it!!! Excellent service"

Reviewed on Nov 3, 2026

Opens in a new windowGrand Hyatt San Francisco
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $404 per night from Nov 22 to Nov 23
CA $404
CA $451 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
Opens in a new windowGrand Hyatt at SFO
Club Quarters Hotel Embarcadero, San Francisco

Club Quarters Hotel Embarcadero, San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Nov 22 to Nov 23
CA $148
CA $174 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (3,532 reviews)
"This is a good hotel in a convenient location. I took public transit into the city, so I have no idea on the parking situation. I needed to go to the Ferry Building and it's a short walk. The place was clean, modern and in good shape I'd stay here again."

Reviewed on Nov 2, 2026

Opens in a new windowClub Quarters Hotel Embarcadero, San Francisco
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4 out of 5
50 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $264 per night from Nov 22 to Nov 23
CA $264
CA $367 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Opens in a new windowHyatt Regency San Francisco Downtown SOMA
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $211 per night from Nov 22 to Nov 23
CA $211
CA $248 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.6/10 Excellent! (1,869 reviews)
"Thank you"

Reviewed on Nov 3, 2026

Opens in a new windowHilton San Francisco Union Square
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Dec 2 to Dec 3
CA $153
CA $237 total
Dec 2 - Dec 3
includes taxes & fees
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (2,891 reviews)
"Location is great"

Reviewed on Nov 3, 2026

Opens in a new windowHotel Zephyr San Francisco
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $194 per night from Nov 23 to Nov 24
CA $194
CA $286 total
Nov 23 - Nov 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
Opens in a new windowHyatt Centric Fisherman's Wharf San Francisco
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Francisco hotel reviews by fellow wanderers

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