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Featured San Francisco 4 Star hotels

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $189 per night from May 25 to May 26
CA $189
CA $279 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,478 reviews)
"Great location"

Reviewed on May 19, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from May 25 to May 26
CA $158
CA $186 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,782 reviews)
"FOR THE AMOUNT OF MONEY SPENT HERE IM APPALLED THE WAY WE WERE TREATED. SECURITY AT OUR DOOR 5 TIMES BEFORE 10:45PM. MY FINACE AND I WERE VISITING SF FOR A PRE WEDDING GETAWAY WITH NO KIDS. HIM AND I ALONE. ASIDE FROM THE FACT I HAVE A VERY ASSERTIVE VOICE THERE IS ABSOLUTLEY NO REASON SECURITY AND ..."

Reviewed on May 18, 2026

Opens in a new windowHilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $186 per night from May 30 to May 31
CA $186
CA $219 total
May 30 - May 31
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,167 reviews)
"No"

Reviewed on May 18, 2026

Opens in a new windowClub Quarters Hotel in San Francisco
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $425 per night from May 26 to May 27
CA $425
CA $474 total
May 26 - May 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.8/10 Exceptional! (1,582 reviews)
"Clean, convenient, and comfortable! Thank you."

Reviewed on May 18, 2026

Opens in a new windowGrand Hyatt at SFO
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

4 out of 5
835 Airport Blvd Burlingame CA
Fully refundableReserve now, pay when you stay
The price is CA $154 per night from May 30 to May 31
CA $154
CA $175 total
May 30 - May 31
includes taxes & fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8.8/10 Excellent! (1,562 reviews)
"Shuttle left 10 minutes early so waited 25 minutes for next one. No instructions for exiting with car at gate. Had to go back to counter. Very good service from Jesus in restaurant...we had limited time and he hustled our food to us."

Reviewed on May 18, 2026

Opens in a new windowDoubleTree by Hilton San Francisco Airport
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $273 per night from May 21 to May 22
CA $273
CA $385 total
May 21 - May 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,234 reviews)
"Everything went smooth. All staff are polite and helpful, customer service is top notch. Valet was great, I have a large truck so leaving it there was great, no issue with size. The room itself was clean, great view of the city and pier. Couldn’t have asked for more. Will be returning soon."

Reviewed on May 18, 2026

Opens in a new windowHyatt Regency San Francisco
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from May 31 to Jun 1
CA $165
CA $194 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and a fitness center. Our guests praise the restaurant ...
8.4/10 Very Good! (2,300 reviews)
"Front desk staff were amazing! I got a Ribeye from the restaurant, not the best quality of meat. Overall, room was clean and beautiful"

Reviewed on May 19, 2026

Opens in a new windowDoubleTree by Hilton San Francisco South Airport Blvd
Stanford Court San Francisco

Stanford Court San Francisco

4 out of 5
905 California Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $217 per night from Jun 7 to Jun 8
CA $217
CA $317 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (1,395 reviews)
"It was an amazing place with a great view!"

Reviewed on May 18, 2026

Opens in a new windowStanford Court San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $242 per night from Jun 7 to Jun 8
CA $242
CA $285 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.4/10 Very Good! (1,314 reviews)
"Very clean and comfortable room. Many restaurants in the area. Be aware that hotel is very large, with most rooms far from elevators."

Reviewed on May 18, 2026

Opens in a new windowHilton San Francisco Union Square
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4 out of 5
450 Powell Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $268 per night from Jun 6 to Jun 7
CA $268
CA $372 total
Jun 6 - Jun 7
includes taxes & fees
Book a stay at this historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (2,027 reviews)
"."

Reviewed on May 18, 2026

Opens in a new windowBeacon Grand, A Union Square Hotel
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4 Star Hotels San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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