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Featured San Mateo 5 Star hotels

Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $284 per night from Jul 5 to Jul 6
CA $284
CA $410 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,551 reviews)
"Water faucet in bathroom was loose but otherwise beautiful hotel. Coffee shop was a bit disappointing."

Reviewed on Jun 24, 2026

Opens in a new windowFairmont San Francisco
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $395 per night from Jul 17 to Jul 18
CA $395
CA $532 total
Jul 17 - Jul 18
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy 2 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,002 reviews)
"Hotel was far from a 5 star hotel. Rooms were dirty and not cleaned well. Hair on the carpet, dust on top of everything. Hallways dirty and dusty. Hot tub water was filled halfway. Very rundown hotel."

Reviewed on Jun 30, 2026

Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $253 per night from Jul 5 to Jul 6
CA $253
CA $347 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (1,000 reviews)
"Always love staying here. Quiet, peaceful and a quick walk to everything fun. Love the breakfast especially the Indian options they have,"

Reviewed on Jun 19, 2026

Opens in a new windowTaj Campton Place
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $654 per night from Jul 31 to Aug 1
CA $654
CA $770 total
Jul 31 - Aug 1
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

5 out of 5
1625 N Shoreline Blvd Mountain View CA
Fully refundableReserve now, pay when you stay
The price is CA $283 per night from Jul 5 to Jul 6
CA $283
CA $311 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this luxury hotel in Mountain View. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,389 reviews)
"Love the welcome glass of champagne! Easy walking to CHM and the theater and Zareens! Beautiful and swanky hotel."

Reviewed on Jun 19, 2026

Opens in a new windowShashi Hotel Mountain View Palo Alto
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $542 per night from Jul 18 to Jul 19
CA $542
CA $706 total
Jul 18 - Jul 19
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,003 reviews)
"The staff is awesome! I can’t wait to comeback!"

Reviewed on Jun 27, 2026

Opens in a new windowThe Ritz-Carlton, San Francisco
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
8 Mission St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $461 per night from Jul 31 to Aug 1
CA $461
CA $623 total
Jul 31 - Aug 1
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (567 reviews)
"Solid hotel."

Reviewed on Jun 27, 2026

Opens in a new window1 Hotel San Francisco
Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

5 out of 5
N. Mathilda, 1100 Sunnyvale CA
Fully refundableReserve now, pay when you stay
The price is CA $250 per night from Jul 19 to Jul 20
CA $250
CA $322 total
Jul 19 - Jul 20
includes taxes & fees
Book a stay at this luxury hotel in Sunnyvale. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions California's Great America and Levi's ...
9.6/10 Exceptional! (112 reviews)
"One of, if not THE nicest hotels I've stayed at while traveling for business. The restaurant was great, the gym is fantastic, the staff are wonderful, and the room was great. Great location too! Not a bad word can be said about this place."

Reviewed on Jun 26, 2026

Opens in a new windowTreehouse Hotel Silicon Valley
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $788 per night from Jul 31 to Aug 1
CA $788
CA $928 total
Jul 31 - Aug 1
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,001 reviews)
"We stay at a lot of Four Seasons and this one seemed just like an average hotel room. It was nice but for the price you pay it should be excellent. The room was just so-so for us. We had to move rooms when we first got there because the toilet was broken. After a long day of traveling that was aggravating. ..."

Reviewed on Jun 26, 2026

Opens in a new windowFour Seasons Hotel San Francisco
The St. Regis San Francisco

The St. Regis San Francisco

5 out of 5
125 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $751 per night from Jul 12 to Jul 13
CA $751
CA $949 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (730 reviews)
"I loved this hotel. Great location, staff, and ambience."

Reviewed on Jun 13, 2026

Opens in a new windowThe St. Regis San Francisco
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Five Star Hotels in San Mateo

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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