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Featured San Mateo 5 Star hotels

Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $468 per night from Oct 11 to Oct 12
CA $468
CA $626 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowFairmont San Francisco
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $313 per night from Oct 4 to Oct 5
CA $313
CA $418 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (1,001 reviews)
"It felt old. Also the food was mediocre"

Reviewed on Sep 25, 2026

Opens in a new windowTaj Campton Place
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $446 per night from Oct 30 to Oct 31
CA $446
CA $591 total
Oct 30 - Oct 31
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy 2 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,003 reviews)
"Horrible service for myself and the couple we traveled with. Prepaid for parking, valet was full, had to park 2 blocks away, not a big deal but annoying. The issue was the staff refused to refund me for the prepaid parking. I was simply told we cannot do it. They refunded something else that was ..."

Reviewed on Sep 28, 2026

Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $577 per night from Oct 23 to Oct 24
CA $577
CA $748 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,006 reviews)
"Wonderful bar staffs."

Reviewed on Sep 29, 2026

Opens in a new windowThe Ritz-Carlton, San Francisco
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

5 out of 5
1625 N Shoreline Blvd Mountain View CA
Fully refundableReserve now, pay when you stay
The price is CA $279 per night from Oct 10 to Oct 11
CA $279
CA $308 total
Oct 10 - Oct 11
includes taxes & fees
Book a stay at this luxury hotel in Mountain View. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and the helpful ...
Opens in a new windowShashi Hotel Mountain View Palo Alto
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
8 Mission St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $636 per night from Oct 30 to Oct 31
CA $636
CA $829 total
Oct 30 - Oct 31
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Opens in a new window1 Hotel San Francisco
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $669 per night from Oct 23 to Oct 24
CA $669
CA $787 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (1,003 reviews)
"We enjoy our stay every time we come."

Reviewed on Sep 28, 2026

Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $657 per night from Oct 9 to Oct 10
CA $657
CA $856 total
Oct 9 - Oct 10
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Opens in a new windowFour Seasons Hotel San Francisco
Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

5 out of 5
2050 University Ave, East Palo Alto Palo Alto CA
Fully refundableReserve now, pay when you stay
The price is CA $483 per night from Oct 9 to Oct 10
CA $483
CA $549 total
Oct 9 - Oct 10
includes taxes & fees
Book a stay at this luxury hotel in Palo Alto. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowFour Seasons Hotel Silicon Valley at East Palo Alto
 The Huntington Hotel

The Huntington Hotel

5 out of 5
1075 California St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $1,133 per night from Oct 11 to Oct 12
CA $1,133
CA $1,408 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and room service. Our guests praise the property condition in our reviews. ...
9.6/10 Exceptional! (37 reviews)
"Ok"

Reviewed on Sep 21, 2026

Opens in a new window The Huntington Hotel
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Five Star Hotels in San Mateo

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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