Book Exclusive De Soto Vacation Packages

Choose one or more items to build your trip:

De Soto flight + hotel packages

Price found within the past 48 hours. Click for updated prices.
Quality Inn & Suites Prairie Du Chien

Quality Inn & Suites Prairie Du Chien

2.5 out of 5
Southside
Price was CA $867, price is now CA $827 per person
CA $827
per person
Jan 3 - Jan 9
found 12 hours ago
Roundtrip flight included
Toronto (YYZ) to La Crosse (LSE)
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Riverside Square and Prairie Cinema are located nearby.
AmericInn by Wyndham Boscobel

AmericInn by Wyndham Boscobel

3 out of 5
Price was CA $965, price is now CA $857 per person
CA $857
per person
Jan 3 - Jan 9
found 12 hours ago
Roundtrip flight included
Toronto (YYZ) to La Crosse (LSE)
Book a stay at this business-friendly hotel in Boscobel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attraction WI River Outings is located nearby.
Comfort Inn & Suites New Lisbon

Comfort Inn & Suites New Lisbon

2.5 out of 5
Price was CA $903, price is now CA $848 per person
CA $848
per person
Jan 3 - Jan 9
found 12 hours ago
Roundtrip flight included
Toronto (YYZ) to La Crosse (LSE)
Book a stay at this business-friendly hotel in New Lisbon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions New Lisbon Memorial Library and Burr Oak Winery are located nearby.
Microtel Inn & Suites by Wyndham Prairie du Chien

Microtel Inn & Suites by Wyndham Prairie du Chien

2.5 out of 5
Southside
Price was CA $937, price is now CA $885 per person
CA $885
per person
Jan 3 - Jan 9
found 12 hours ago
Roundtrip flight included
Toronto (YYZ) to La Crosse (LSE)
Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Prairie Cinema and Riverside Square are located nearby.
Country Inn & Suites by Radisson, Prairie du Chien

Country Inn & Suites by Radisson, Prairie du Chien

3 out of 5
Price was CA $963, price is now CA $913 per person
CA $913
per person
Jan 3 - Jan 9
found 12 hours ago
Roundtrip flight included
Toronto (YYZ) to La Crosse (LSE)
Book a stay at this family-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Limery Ridge Savanna State Natural Area and Barnyard 9 Golf Course are located nearby.

Top De Soto hotels deals

Mississippi Cabin with Boat dock

Mississippi Cabin with Boat dock

De Soto WI
Get rates
Stay at this cabin in De Soto. Enjoy laundry facilities and air conditioning. Popular attractions Big Lake and Lansing Wildlife Management Area are located nearby.
Kitchen
Washer
Rustic Hideaway Sleeps 4 HOT TUB

Rustic Hideaway Sleeps 4 HOT TUB

De Soto WI
The price is CA $296 per night
CA $296
CA $568 total
Oct 25 - Oct 26
includes taxes & fees
Stay at this cabin in De Soto. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Big Lake and Lansing Wildlife Management Area are located nearby.
Hot tub
Kitchen
Paradise Point- Sleeps 2 HOT TUB

Paradise Point- Sleeps 2 HOT TUB

De Soto WI
The price is CA $329 per night
CA $329
CA $569 total
Oct 29 - Oct 30
includes taxes & fees
Stay at this cabin in De Soto. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Big Lake and Mount Hosmer Park are located nearby.
Hot tub
Kitchen
NEWLY REMODELED HOME! INDOOR FISH & GAME CLEANING STATION!

NEWLY REMODELED HOME! INDOOR FISH & GAME CLEANING STATION!

De Soto WI
Get rates
Stay at this vacation home in De Soto. Enjoy laundry facilities and air conditioning. Popular attractions Big Lake and Lansing Wildlife Management Area are located nearby.
Kitchen
Washer
Gundersen Hotel & Suites

Gundersen Hotel & Suites

2.5 out of 5
1520 Clinic Court La Crosse WI
Free cancellation
Reserve now, pay when you stay
The price is CA $111 per night
CA $111
CA $128 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in La Crosse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions La Crosse Center and City Brewery are located nearby.
Pool
Breakfast included
Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Ferryville WI
Get rates
Enjoy free WiFi, a garden, and patios. Our guests praise the helpful staff in our reviews. Popular attractions Big Lake and Black Hawk Bridge are located nearby.
Hot tub
Kitchen
Don't see what you're looking for?
See all available properties in De Soto
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Vacations

A little bit of planning and research can mean the difference between a run-of-the-mill vacation and an amazing one! Wander wisely in De Soto by knowing a few details about it before you hurry off.

It's located 25 miles (40 kilometers) away from La Crosse and 30 miles (48 kilometers) away from Prairie Du Chien.

It won't be too hard to make some new buddies in this part of Wisconsin. It boasts a population of about 300 locals.

Places to visit in De Soto

Feel like clearing your mind in the great outdoors? The large open space at Clear Creek Park is the ideal place to play some games or simply sit back and put your feet up. After you've seen the sights, get outdoors and go skiing. It's a fun way to experience a different side of the wider region.

Where do you fly into for De Soto?

Put your seat in the upright position, fasten your seatbelt and get ready to explore De Soto! Once you touch down at La Crosse Municipal Airport (LSE), the busy main streets will be just 30 miles (48 kilometers) to the south from here.

Frequently asked questions

How much are vacation packages to De Soto?
Travelocity offers great package deals to De Soto, including flights and hotels, starting from as low as CA $827. With the money you save, you could purchase some cool tours or possibly even add a couple of extra days to your adventure.
Where can I get the best vacation package deals for De Soto?
Grabbing an amazing package deal to De Soto couldn't be easier with Travelocity. With as many as 400 air carriers and 665,000 properties around the world, you're spoiled for choice when picking your flights and hotels.
Why should I purchase my De Soto vacation package via Travelocity?
Travel should be about making fantastic new memories and leaving all your troubles behind — which is why we have a team of experts on hand around-the-clock should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best deal available on our impressive range of getaway packages. So what are you waiting for? There's no time like the present to secure the vacation you've always dreamed of.
Can I save on my De Soto car rental if I bundle it with a hotel or flight?
Absolutely — bundle your hotel, flight and car into a De Soto vacation package and you can save a handsome sum. With so many things to do in the De Soto area, having your own ride will make exploring easy. Once you've buckled yourself in, crank up the tunes and cruise toward University of Wisconsin-Madison, a renowned sight approximately 150 kilometersfrom De Soto.
What is the best time of year to go to De Soto?
If you're eager to avoid costly airfares, big crowds and sold-out hotels, organize your trip outside of . The quietest time to travel through De Soto is . You'll find hotel rates are the highest in and the most affordable in .
Which airport is best for De Soto?
La Crosse, WI (LSE-La Crosse Municipal) is the arrival point for travelers flying to De Soto. Once you step off the plane, you'll find yourself 45 kilometersnorth of downtown.
Where should I stay when visiting De Soto?
The Secluded Cabin Just Minutes From The Mississippi River!! is popular with many travelers. Book soon before it's too late.
Can I go on vacation to De Soto at this time?
Don't head to De Soto without up-to-date facts about travel restrictions and quarantine policies. Travelocity's Covid-19 Travel Advisor will fill in the blanks. It has all the info you need to make your vacation plans as relaxed as possible.

Photos of local treasures

Browse De Soto vacation photos for more inspiration

A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.