Isla Grande Vacations 2026 from CA $1,260

Isla Grande flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Villa Botero By Casa Mojito B&B

CA $1,260

per person

Apr 19 - Apr 26

found 1 day ago

Roundtrip non-stop flight included

Ottawa (YOW) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Santa Clara Beach are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

CA $2,019

per person

May 16 - May 23

found 13 hours ago

Roundtrip non-stop flight included

Detroit (DTW) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cinta Costera and Amador Causeway are located nearby.

Casa Mallet by Wynwood House

Casco Viejo

CA $1,795

per person

May 9 - May 16

found 20 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

San Francisco

CA $1,950

per person

May 16 - May 23

found 13 hours ago

Roundtrip non-stop flight included

Detroit (DTW) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Avenida Balboa and Via Espana are located nearby.

Villa Marina Hotel

CA $1,302

per person

Apr 19 - Apr 26

found 1 day ago

Roundtrip non-stop flight included

Ottawa (YOW) to Panama City (PTY)

Book a stay at this beach inn in Las Escobas del Venado. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.

Top Isla Grande hotels deals

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

Get rates

Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Spa

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Free cancellation

Reserve now, pay when you stay

CA $86

CA $155 total

Mar 4 - Mar 5

includes taxes & fees

Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Breakfast included

Pet-friendly

Ordovician Beach Resort

Isla Grande Isla Grande Colon

CA $668

CA $737 total

Mar 6 - Mar 7

includes taxes & fees

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

On private beach

Pool

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province Colón Province

CA $462

CA $524 total

Mar 3 - Mar 4

includes taxes & fees

Stay at this vacation home in Isla Grande. Enjoy air conditioning. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pet-friendly

Air conditioning

Brother Sun Villas

Camino Al Faro Isla Grande

Get rates

Book a stay at this beach vacation home in Isla Grande. Enjoy a beach locale, daily housekeeping, and a garden. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Kitchen

Casa Congo - Rayo Verde - Restaurante

Calle Genea Portobelo

Free cancellation

Reserve now, pay when you stay

CA $95

CA $106 total

Mar 10 - Mar 11

includes taxes & fees

Book a stay at this beach B&B in Portobelo. Enjoy free breakfast, an airport shuttle (surcharge), and daily housekeeping. Popular attractions Fuerte San Jerónimo and San Felipe Church are located nearby.

Breakfast included

Free WiFi

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See all available properties in Isla Grande

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Isla Grande?

CA $1,260 is all you need to spend for a memorable vacation in Isla Grande. Bundle your hotel and flights into a vacation package with Travelocity and see your savings add up. With such good prices, it's never been more tempting to travel.

Where can I get the best vacation package deals for Isla Grande?

With around 400 partner airlines and 1,000,000 properties around the world, it's hard to beat Travelocity. Browse our comprehensive range and pick up the best Isla Grande vacation package. Isn't it amazing when trip planning is that easy?

Why should I purchase my Isla Grande vacation package via Travelocity?

Because you'll never roam alone if you secure your trip with us, and we offer round-the-clock support and exceptional service to boot. Add to that our Price Match Guarantee and a massive range of destinations to select from. We're here to help you have the vacation of a lifetime.

Will I save money on my Isla Grande car rental if I bundle it with a hotel or flight?

Certainly. And our Isla Grande vacation packages are the best way to do it. With only a few clicks you can save cash and time by bundling your bookings. Collect the keys to your rental car and feel the freedom of the open road. Need to fill your itinerary? Add some activities or experiences to your package and make savings on those too.