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Featured Santa Cruz 3 Star hotels

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is CA $70 per night from Jan 2 to Jan 3
CA $70
CA $70 total
Jan 2 - Jan 3
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (78 reviews)
Good place in decent area and good price for the area

Reviewed on Dec 17, 2025

Opens in a new windowIbis Santa Cruz DE LA Sierra
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13 Santa Cruz Santa Cruz
The price is CA $123 per night from Jan 2 to Jan 3
CA $123
CA $123 total
Jan 2 - Jan 3
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (332 reviews)
spotless

Reviewed on Dec 9, 2025

Opens in a new windowSun Hotel
Hotel Las Américas

Hotel Las Américas

3 out of 5
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
The price is CA $53 per night from Jan 7 to Jan 8
CA $53
CA $53 total
Jan 7 - Jan 8
Stay at this hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions La Recova Artisan Walk and Guarani Nandereko ...
6/10 (1 review)
Hotel mediano, ótima localização
O chuveiro foi impossível tomar um.banho de qualidade

Reviewed on Jul 29, 2025

Opens in a new windowHotel Las Américas
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is CA $179 per night from Jan 30 to Jan 31
CA $179
CA $179 total
Jan 30 - Jan 31
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (345 reviews)
Great spacious property with nice pool!

Reviewed on Dec 15, 2025

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

3.5 out of 5
Calle Pablo Sanz 29 Equipetrol Santa Cruz
The price is CA $58 per night from Jan 9 to Jan 10
CA $58
CA $58 total
Jan 9 - Jan 10
Stay at this hotel in Santa Cruz. Enjoy free WiFi, room service, and daily housekeeping. Popular attractions Ventura Mall and Santa Cruz Zoo are located ...
9/10 Wonderful! (73 reviews)
Todo excelente como siempre. Merece la pena regresar

Reviewed on Oct 31, 2025

Opens in a new windowDelfines Collection Hotel By Mercure
Senses Boutique Hotel

Senses Boutique Hotel

3.5 out of 5
Calle 24 de Septiembre, Esq. Sucre No 5 Santa Cruz
Book a stay at this family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Franco Aleman Cultural ...
Very large and confortable rooms in central location. Breakfast could be better but staff is very friendly and helpful

Reviewed on Apr 3, 2023

Opens in a new windowSenses Boutique Hotel
Hotel Cortez

Hotel Cortez

3.5 out of 5
Av. Cristobal de Mendoza 280 Santa Cruz
The price is CA $166 per night from Feb 1 to Feb 2
CA $166
CA $166 total
Feb 1 - Feb 2
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Municipal Library and Arenal Park are located ...
9/10 Wonderful! (124 reviews)
The staff and property are second to none!

Reviewed on Jun 14, 2025

Opens in a new windowHotel Cortez
HOTEL OSHO

HOTEL OSHO

3.5 out of 5
751 Ave Suarez Arana Santa Cruz Departamento de Santa Cruz
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Santa Cruz de la Sierra ...
9.2/10 Wonderful! (36 reviews)
Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!

Reviewed on Dec 8, 2025

Opens in a new windowHOTEL OSHO
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45 Santa Cruz
Book a stay at this business-friendly apartment in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle Center ...
8.6/10 Excellent! (94 reviews)
Yes, staff were very friendly

Reviewed on Dec 29, 2025

Opens in a new windowApart Hotel Premium Suites Santa Cruz
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol Santa Cruz
Stay at this hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are located ...
8/10 Very Good! (201 reviews)
So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good.

Reviewed on Feb 21, 2025

Opens in a new windowHotel LP Equipetrol
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3 Star Hotels Santa Cruz

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Santa Cruz that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Santa Cruz 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Santa Cruz today!

Recent Santa Cruz hotel reviews by fellow wanderers