Find and compare 4 Star hotels in Antigua Guatemala

Name: Mestizo Antigua
Price range: CA $225
Rating: 9.4

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Featured Antigua Guatemala 4 Star hotels

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

CA $379

CA $479 total

Nov 17 - Nov 18

includes taxes & fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (1,009 reviews)

One of the best hotels i stayed at! Amazingly beautiful, enormous quiet rooms, great restaurant and spa facilities, lots of ruins and museums

Reviewed on Nov 14, 2025

Porta Hotel Antigua

8va Calle Poniente No1 Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

CA $227

CA $291 total

Nov 17 - Nov 18

includes taxes & fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...

9.2/10 Wonderful! (1,000 reviews)

The room was spotless, love the purified water in the room. The pool was beautifully and the staff was attentive. We had an excellent stay!

Reviewed on Nov 12, 2025

Hotel Camino Real Antigua

7a Calle Poniente 33B Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

CA $215

CA $298 total

Dec 14 - Dec 15

includes taxes & fees

Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...

9.6/10 Exceptional! (1,002 reviews)

everything was perfect

Reviewed on Nov 3, 2025

El Convento Boutique Hotel

2a Avenida Norte No. 11 Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

CA $245

CA $320 total

Nov 17 - Nov 18

includes taxes & fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (785 reviews)

Super comfortable stay, loved the atmosphere and the restaurant was great. Would def go here again

Reviewed on Nov 10, 2025

Hotel Soleil La Antigua

9 Calle Poniente Antigua Guatemala Sacatepequez

Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the property ...

8.6/10 Excellent! (1,002 reviews)

Clean room. Spacious.

Reviewed on Nov 15, 2025

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Hotel Casa Carmina

9a Calle Poniente No. 17 Antigua Guatemala Sacatepéquez

CA $234

CA $285 total

Nov 22 - Nov 23

includes taxes & fees

Stay at this 4-star business-friendly hotel in Antigua Guatemala. Enjoy breakfast (surcharge), room service, and onsite spa services. Popular attractions Central ...

8.8/10 Excellent! (193 reviews)

What an amazing place

Reviewed on Nov 14, 2025

Los Pasos Boutique Hotel & Spa

9 Calle Oriente No. 19 Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

CA $183

CA $228 total

Dec 14 - Dec 15

includes taxes & fees

Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...

9.4/10 Exceptional! (1,000 reviews)

Fast and early checkin! Received a discount for food. Delicious restaurant, beautiful, quiet and spacious room. Hot shower. I got a great massage at the spa too!

Reviewed on Nov 11, 2025

San Rafael Hotel

2da calle Poniente No.7 Antigua, Antigua Guatemala, Sacatepequez

Fully refundableReserve now, pay when you stay

CA $278

CA $344 total

Nov 17 - Nov 18

includes taxes & fees

Stay at this 4-star boutique hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the ...

9.8/10 Exceptional! (430 reviews)

A beautifully maintained traditional hotel. The room was spacious, it was very peaceful and had a lovely fragrance from all the lovely fresh flowers. The location was excellent. They lit candles in the courtyard in the evening which was delightful. The staff at the hotel were excellent. Professional ...

Reviewed on Nov 10, 2025

Las Cruces Boutique Hotel

3a Calle Oriente Casa No. 4, Antigua Guatemala, Sacatepéquez

Fully refundableReserve now, pay when you stay

CA $351

CA $428 total

Nov 17 - Nov 18

includes taxes & fees

Stay at this 4-star business-friendly hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...

9.8/10 Exceptional! (216 reviews)

Immaculate hotel! We loved everything about the hotel and the location was perfect for getting everywhere. The hotel has stunning architecture and beautiful artwork. Staff was wonderful. Favorite place we stayed in Guatemala and would definitely come back.

Reviewed on Nov 11, 2025

Mestizo Antigua

6a Avenida Norte # 2, Antigua Guatemala

Fully refundableReserve now, pay when you stay

CA $225

CA $275 total

Nov 28 - Nov 29

includes taxes & fees

Stay at this 4-star spa hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

9.4/10 Exceptional! (151 reviews)

Manly was very helpful. Amazing customer service to all the staff

Reviewed on Nov 1, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Antigua Guatemala

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Antigua Guatemala 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Antigua Guatemala will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Antigua Guatemala, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.