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Featured Brindisi 4 Star hotels

Grand Hotel di Lecce

Grand Hotel di Lecce

4 out of 5
Via Oronzo Quarta 28 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from Feb 15 to Feb 16
CA $129
CA $149 total
Feb 15 - Feb 16
includes taxes & fees
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Railway Museum of Puglia and Sigismondo Castromediano ...
8.2/10 Very Good! (306 reviews)
Wonderful stay
Breakfast was incredible and plentiful. Fresh fruit and vegetables with Salento products. Room was spacious but a bit outdated. However that is the style of the hotel. We could not use the pool due to bad weather but the pool area seemed nice.

Reviewed on Oct 2, 2025

Opens in a new windowGrand Hotel di Lecce
Grand Hotel Tiziano e dei Congressi

Grand Hotel Tiziano e dei Congressi

4 out of 5
1 Viale Porta D Europa Lecce LE
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Popular attractions City Walls and Chiesa dei Santi Nicolo e Cataldo ...
7.2/10 Good! (435 reviews)
nice

Reviewed on Sep 18, 2025

Opens in a new windowGrand Hotel Tiziano e dei Congressi
Hotel Orientale

Hotel Orientale

4 out of 5
C.so Garibaldi, 40 Brindisi BR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (454 reviews)
A very good hotel in an excellent location. Clean, spacious, modern room. A very good breakfast buffet with a lot of selections. What is most noteworthy is the staff. Andre and his wife at the reception desk were welcoming, personable and very helpful with local knowledge and advice. At breakfast ...

Reviewed on Dec 18, 2025

Opens in a new windowHotel Orientale
Palazzo Virgilio

Palazzo Virgilio

4 out of 5
Corso Umberto I, 149 Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $172 per night from Feb 12 to Feb 13
CA $172
CA $195 total
Feb 12 - Feb 13
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free WiFi, 24-hour room service, and parking (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (359 reviews)
Quite a nice hotel in a very good location for the train. The room was quite large and clean and the bathroom too. However the carpets in the hallway were rather dirty and this gave a negative first impression that would be easy to fix with a deep clean. Breakfast was not bad - the pastries were ...

Reviewed on Nov 27, 2025

Opens in a new windowPalazzo Virgilio
Hotel Executive Inn

Hotel Executive Inn

4 out of 5
Via Pozzo Traiano, 24 Brindisi BR
Fully refundableReserve now, pay when you stay
Stay at this hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Piazza ...
9.2/10 Wonderful! (320 reviews)
Very nice staff

Reviewed on Jan 11, 2026

Opens in a new windowHotel Executive Inn
Grande Albergo Internazionale

Grande Albergo Internazionale

4 out of 5
Lungomare Regina Margherita Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Mar 2 to Mar 3
CA $176
CA $201 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (416 reviews)
Yes

Reviewed on Jan 5, 2026

Opens in a new windowGrande Albergo Internazionale
Mercure Hotel President Lecce

Mercure Hotel President Lecce

4 out of 5
Via Antonio Salandra, 6 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Feb 8 to Feb 9
CA $145
CA $160 total
Feb 8 - Feb 9
includes taxes & fees
Book a stay at this business-friendly hotel in Lecce. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Chinese Missionary Museum ...
7.8/10 Good! (320 reviews)
The staff: efficient professional caring resourceful friendly supportive Great breakfast Great location Awesome rooms quiet

Reviewed on Apr 15, 2025

Opens in a new windowMercure Hotel President Lecce
Pollicastro Boutique Hotel

Pollicastro Boutique Hotel

4 out of 5
Via dei Perroni, 14 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $251 per night from Feb 10 to Feb 11
CA $251
CA $283 total
Feb 10 - Feb 11
includes taxes & fees
Book a stay at this boutique hotel in Lecce. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (139 reviews)
The whole experience was top notch. Friendly, helpful staff, comfortable room, delicious breakfast, and location was perfect for getting around the city.

Reviewed on Jan 21, 2026

Opens in a new windowPollicastro Boutique Hotel
Hotel Delle Palme

Hotel Delle Palme

4 out of 5
Via Leuca 90 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from Feb 8 to Feb 9
CA $158
CA $180 total
Feb 8 - Feb 9
includes taxes & fees
Book a stay at this business-friendly hotel in Lecce. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Torre del Parco and ...
8.6/10 Excellent! (176 reviews)
Super clean

Reviewed on Nov 8, 2025

Opens in a new windowHotel Delle Palme
8Piuhotel

8Piuhotel

4 out of 5
Viale Del Risorgimento 3 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $181 per night from Feb 27 to Feb 28
CA $181
CA $205 total
Feb 27 - Feb 28
includes taxes & fees
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Chiesa ...
9.6/10 Exceptional! (764 reviews)
I loved my stay at this hotel

Reviewed on Jan 2, 2026

Opens in a new window8Piuhotel
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4 Star Hotels Brindisi

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Brindisi 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Brindisi will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Brindisi, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Brindisi hotel reviews by fellow wanderers