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Featured Brindisi 4 Star hotels

Palazzo Virgilio

Palazzo Virgilio

4 out of 5
Corso Umberto I, 149 Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $142 per night from May 21 to May 22
CA $142
CA $166 total
May 21 - May 22
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free WiFi, 24-hour room service, and parking (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (378 reviews)
"This hotel was exactly what I needed exactly when I needed it. Hotel staff fielded questions about posting parcels, got me a sewing kit, and made me cappuccino in the morning. The breakfast might have a juicer (didn't my second morning) but had truly tasty things to eat and the lightest scrambled ..."

Reviewed on May 18, 2026

Opens in a new windowPalazzo Virgilio
Hotel Orientale

Hotel Orientale

4 out of 5
C.so Garibaldi, 40 Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $194 per night from May 22 to May 23
CA $194
CA $224 total
May 22 - May 23
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (465 reviews)
"This was a very nice hotel with amazingly helpful staff. The rooms were comfortable and it was great to be able to open the window. I would definitely stay again."

Reviewed on May 6, 2026

Opens in a new windowHotel Orientale
Ostuni a Mare

Ostuni a Mare

4 out of 5
Rosa Marina - C.P. n. 82 Ostuni BR
The price is CA $435 per night from Jun 18 to Jun 19
CA $435
CA $488 total
Jun 18 - Jun 19
includes taxes & fees
Book a stay at this beach hotel in Ostuni. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Popular attractions Rosa Marina Beach and Torre Canne Beach ...
9/10 Wonderful! (61 reviews)
"Beautiful clean facilities, with three pools and access to the beach Excellent breakfast options. Rooms were clean. Two restaurant options. It's an oasis in Puglia."

Reviewed on Sep 30, 2025

Opens in a new windowOstuni a Mare
Grande Albergo Internazionale

Grande Albergo Internazionale

4 out of 5
Lungomare Regina Margherita Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $191 per night from May 25 to May 26
CA $191
CA $219 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (448 reviews)
"At the night, we found the air conditioner was not working in a hot season and the staff in no good manner said that they doesn’t have solution until next’s day. We asked for a room change and as well the answer was not appropriate. The hotel is beautiful, but the night staff not."

Reviewed on May 18, 2026

Opens in a new windowGrande Albergo Internazionale
Best Western Plus Leone di Messapia Hotel & Conference

Best Western Plus Leone di Messapia Hotel & Conference

4 out of 5
Provinciale Lecce Cavallino 32 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $169 per night from Jun 9 to Jun 10
CA $169
CA $200 total
Jun 9 - Jun 10
includes taxes & fees
Book a stay at this family-friendly hotel in Lecce. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Torre del Parco and Casa Museo ...
9.4/10 Exceptional! (155 reviews)
"Clean room and quiet location. Property was very well maintained. Very helpful staff."

Reviewed on Nov 28, 2025

Opens in a new windowBest Western Plus Leone di Messapia Hotel & Conference
Arthotel & Park Lecce

Arthotel & Park Lecce

4 out of 5
Via Giorgio de Chirico, 1 Lecce LE
The price is CA $129 per night from May 25 to May 26
CA $129
CA $157 total
May 25 - May 26
includes taxes & fees
Book a stay at this spa hotel in Lecce. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Torre del Parco and Casa Museo Spada are located ...
8.4/10 Very Good! (172 reviews)
"Staff member checking us in was unfamiliar with SERVICE dogs. That created a little friction, but was resolved. The room was comfortable, except for loud mechanical noises all night. The water pressure is excellent, but the shower is a bit small. The breakfast was adequate."

Reviewed on Apr 9, 2026

Opens in a new windowArthotel & Park Lecce
Grand Hotel Tiziano e dei Congressi

Grand Hotel Tiziano e dei Congressi

4 out of 5
1 Viale Porta D Europa Lecce LE
The price is CA $134 per night from May 24 to May 25
CA $134
CA $162 total
May 24 - May 25
includes taxes & fees
Book a stay at this spa hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Popular attractions City Walls and Chiesa dei Santi Nicolo e Cataldo ...
7.4/10 Good! (459 reviews)
"We stayed three nights. The room had dust on the floor and I stepped on a toe nail (not mine) in the bathroom. The bathroom floor tiles were badly cracked. The shower over bath had no screen. Breakfast was ok - not great but ok. Staff were ok. The AC came on automatically what appeared to be randomly. ..."

Reviewed on May 12, 2026

Opens in a new windowGrand Hotel Tiziano e dei Congressi
Le Dune Suite Hotel

Le Dune Suite Hotel

4 out of 5
Strada Dei Bacini 72 Porto Cesareo LE
The price is CA $195 per night from May 19 to May 20
CA $195
CA $220 total
May 19 - May 20
includes taxes & fees
Book a stay at this beach hotel in Porto Cesareo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Torre Lapillo Beach and Lapillo Sea ...
8.6/10 Excellent! (63 reviews)
"Great hotel, with a beautiful private beach. Pool are was beautiful too. Really enjoyed our stay here."

Reviewed on May 2, 2026

Opens in a new windowLe Dune Suite Hotel
Hotel Executive Inn

Hotel Executive Inn

4 out of 5
Via Pozzo Traiano, 24 Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from May 29 to May 30
CA $187
CA $216 total
May 29 - May 30
includes taxes & fees
Stay at this hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Port ...
9.4/10 Exceptional! (330 reviews)
"All travelers who come to spend a night or two in Brindisi should consider staying at Executive Inn. We found our room very satisfactory & the included breakfast quite satisfying."

Reviewed on Apr 6, 2026

Opens in a new windowHotel Executive Inn
Ostuni Palace Hotel Ristorante & SPA

Ostuni Palace Hotel Ristorante & SPA

4 out of 5
Corso Vittorio Emanuele 218 Ostuni BR
Fully refundableReserve now, pay when you stay
The price is CA $267 per night from May 19 to May 20
CA $267
CA $304 total
May 19 - May 20
includes taxes & fees
Book a stay at this spa hotel in Ostuni. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Piazza della Liberta and Museum of Preclassical ...
9.2/10 Wonderful! (158 reviews)
"Perfect place to stay with parking on site just on the edge of the Centro Storico. Staff great. Try to get the room with a view of the White City. Loved Ostuni."

Reviewed on May 9, 2026

Opens in a new windowOstuni Palace Hotel Ristorante & SPA
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4 Star Hotels Brindisi

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Brindisi 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Brindisi will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Brindisi, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Brindisi hotel reviews by fellow wanderers