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Featured Brindisi 4 Star hotels

Palazzo Virgilio

Palazzo Virgilio

4 out of 5
Corso Umberto I, 149 Brindisi BR
The price is CA $160 per night from Apr 8 to Apr 9
CA $160
CA $186 total
Apr 8 - Apr 9
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free WiFi, 24-hour room service, and parking (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (368 reviews)
Quite a nice hotel in a very good location for the train. The room was quite large and clean and the bathroom too. However the carpets in the hallway were rather dirty and this gave a negative first impression that would be easy to fix with a deep clean. Breakfast was not bad - the pastries were ...

Reviewed on Nov 27, 2025

Opens in a new windowPalazzo Virgilio
8Piuhotel

8Piuhotel

4 out of 5
Viale Del Risorgimento 3 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $181 per night from Apr 2 to Apr 3
CA $181
CA $214 total
Apr 2 - Apr 3
includes taxes & fees
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Chiesa ...
9.6/10 Exceptional! (789 reviews)
I loved my stay at this hotel

Reviewed on Jan 2, 2026

Opens in a new window8Piuhotel
Mercure Hotel President Lecce

Mercure Hotel President Lecce

4 out of 5
Via Antonio Salandra, 6 Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $130 per night from Apr 2 to Apr 3
CA $130
CA $158 total
Apr 2 - Apr 3
includes taxes & fees
Book a stay at this business-friendly hotel in Lecce. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Chinese Missionary Museum ...
8/10 Very Good! (335 reviews)
I have no complaints about this property. My overall experience was great. The staff were all very professional, and the room was spotless—including the bedsheets and towels. The bed itself was very comfortable, the breakfast was high quality, great water pressure and consistent hot water in the ...

Reviewed on Mar 30, 2026

Opens in a new windowMercure Hotel President Lecce
Grand Hotel Tiziano e dei Congressi

Grand Hotel Tiziano e dei Congressi

4 out of 5
1 Viale Porta D Europa Lecce LE
Fully refundableReserve now, pay when you stay
The price is CA $111 per night from Apr 2 to Apr 3
CA $111
CA $136 total
Apr 2 - Apr 3
includes taxes & fees
Book a stay at this spa hotel in Lecce. Enjoy free breakfast, free WiFi, and free parking. Popular attractions City Walls and Chiesa dei Santi Nicolo e Cataldo ...
7.4/10 Good! (454 reviews)
nice

Reviewed on Sep 18, 2025

Opens in a new windowGrand Hotel Tiziano e dei Congressi
Grand Hotel di Lecce

Grand Hotel di Lecce

4 out of 5
Via Oronzo Quarta 28 Lecce LE
The price is CA $117 per night from Apr 8 to Apr 9
CA $117
CA $143 total
Apr 8 - Apr 9
includes taxes & fees
Stay at this hotel in Lecce. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Railway Museum of Puglia and Sigismondo Castromediano ...
Opens in a new windowGrand Hotel di Lecce
Hotel Orientale

Hotel Orientale

4 out of 5
C.so Garibaldi, 40 Brindisi BR
Fully refundableReserve now, pay when you stay
The price is CA $182 per night from Apr 17 to Apr 18
CA $182
CA $209 total
Apr 17 - Apr 18
includes taxes & fees
Book a stay at this business-friendly hotel in Brindisi. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (458 reviews)
Our room was very dated and drab. There was no English Sky channels and the breakfast was very poor with mainly just cakes and pastries and cheap sliced bread.

Reviewed on Jan 21, 2026

Opens in a new windowHotel Orientale
Ostuni a Mare

Ostuni a Mare

4 out of 5
Rosa Marina - C.P. n. 82 Ostuni BR
Book a stay at this beach hotel in Ostuni. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Popular attractions Rosa Marina Beach and Spiaggia di Monticelli ...
9/10 Wonderful! (61 reviews)
Beautiful clean facilities, with three pools and access to the beach Excellent breakfast options. Rooms were clean. Two restaurant options. It's an oasis in Puglia.

Reviewed on Sep 30, 2025

Opens in a new windowOstuni a Mare
Borgo Canonica

Borgo Canonica

4 out of 5
Contrada Minetta, 20 Cisternino BR
Fully refundableReserve now, pay when you stay
The price is CA $231 per night from Apr 9 to Apr 10
CA $231
CA $261 total
Apr 9 - Apr 10
includes taxes & fees
Book a stay at this business-friendly hotel in Cisternino. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mary Immaculate Ecclesiastical ...
Opens in a new windowBorgo Canonica
Ostuni Palace Hotel Bistrot & SPA

Ostuni Palace Hotel Bistrot & SPA

4 out of 5
Corso Vittorio Emanuele 218 Ostuni BR
Fully refundableReserve now, pay when you stay
The price is CA $230 per night from Apr 24 to Apr 25
CA $230
CA $263 total
Apr 24 - Apr 25
includes taxes & fees
Book a stay at this spa hotel in Ostuni. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Piazza della Liberta and Museum of Preclassical ...
9.2/10 Wonderful! (149 reviews)
The hotel was stunning and the staff was very kind. We had a wonderful trip and would love to come back!

Reviewed on Dec 30, 2025

Opens in a new windowOstuni Palace Hotel Bistrot & SPA
Hotel Monte Sarago

Hotel Monte Sarago

4 out of 5
Corso Mazzini 233 Ostuni BR
Fully refundableReserve now, pay when you stay
The price is CA $174 per night from Apr 2 to Apr 3
CA $174
CA $201 total
Apr 2 - Apr 3
includes taxes & fees
Book a stay at this spa hotel in Ostuni. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (275 reviews)
Good

Reviewed on Mar 31, 2026

Opens in a new windowHotel Monte Sarago
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4 Star Hotels Brindisi

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Brindisi 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Brindisi will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Brindisi, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Brindisi hotel reviews by fellow wanderers